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Daniela Di Paolo
Daniela Di Paolo
Research Scientist, IRCCS Istituto G. Gaslini,Lab. Exp. Therapy in Oncology, Department of
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Year
Targeting liposomal chemotherapy via both tumor cell–specific and tumor vasculature–specific ligands potentiates therapeutic efficacy
F Pastorino, C Brignole, D Di Paolo, B Nico, A Pezzolo, D Marimpietri, ...
Cancer research 66 (20), 10073-10082, 2006
2902006
Effect of bortezomib on human neuroblastoma cell growth, apoptosis, and angiogenesis
C Brignole, D Marimpietri, F Pastorino, B Nico, D Di Paolo, M Cioni, ...
Journal of the National Cancer Institute 98 (16), 1142-1157, 2006
1572006
Targeting macrophages as a potential therapeutic intervention: impact on inflammatory diseases and cancer
M Ponzoni, F Pastorino, D Di Paolo, P Perri, C Brignole
International journal of molecular sciences 19 (7), 1953, 2018
1532018
Enhanced antitumor efficacy of clinical-grade vasculature-targeted liposomal doxorubicin
F Pastorino, D Di Paolo, F Piccardi, B Nico, D Ribatti, A Daga, G Baio, ...
Clinical Cancer Research 14 (22), 7320-7329, 2008
1092008
A novel liposomal Clodronate depletes tumor-associated macrophages in primary and metastatic melanoma: Anti-angiogenic and anti-tumor effects
F Piaggio, V Kondylis, F Pastorino, D Di Paolo, P Perri, I Cossu, F Schorn, ...
Journal of Controlled Release 223, 165-177, 2016
1052016
Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma
M Loi, S Marchiò, P Becherini, D Di Paolo, M Soster, F Curnis, C Brignole, ...
Journal of controlled release 145 (1), 66-73, 2010
912010
Combined therapeutic effects of vinblastine and rapamycin on human neuroblastoma growth, apoptosis, and angiogenesis
D Marimpietri, C Brignole, B Nico, F Pastorino, A Pezzolo, F Piccardi, ...
Clinical Cancer Research 13 (13), 3977-3988, 2007
882007
Therapeutic targeting of TLR9 inhibits cell growth and induces apoptosis in neuroblastoma
C Brignole, D Marimpietri, DD Paolo, P Perri, F Morandi, F Pastorino, ...
Cancer research 70 (23), 9816-9826, 2010
862010
Neuroblastoma-targeted nanoparticles entrapping siRNA specifically knockdown ALK
D Di Paolo, C Brignole, F Pastorino, R Carosio, A Zorzoli, M Rossi, M Loi, ...
Molecular Therapy 19 (6), 1131-1140, 2011
782011
Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma
D Di Paolo, C Ambrogio, F Pastorino, C Brignole, C Martinengo, ...
Molecular Therapy 19 (12), 2201-2212, 2011
762011
A proof-of-concept for epigenetic therapy of tissue fibrosis: inhibition of liver fibrosis progression by 3-deazaneplanocin A
M Zeybel, S Luli, L Sabater, T Hardy, F Oakley, J Leslie, A Page, ...
Molecular Therapy 25 (1), 218-231, 2017
742017
PHOX2B-Mediated Regulation of ALK Expression: In Vitro Identification of a Functional Relationship between Two Genes Involved in Neuroblastoma
T Bachetti, D Di Paolo, S Di Lascio, V Mirisola, C Brignole, M Bellotti, ...
PloS one 5 (10), e13108, 2010
702010
The use of the orthotopic model to validate antivascular therapies for cancer.
M Loi, D Di Paolo, P Becherini, A Zorzoli, P Perri, R Carosio, M Cilli, ...
International Journal of Developmental Biology 55, 2011
612011
Tumor vascular targeted liposomal-bortezomib minimizes side effects and increases therapeutic activity in human neuroblastoma
G Zuccari, A Milelli, F Pastorino, M Loi, A Petretto, A Parise, C Marchetti, ...
Journal of controlled release 211, 44-52, 2015
602015
Neuroblastoma targeting by c-myb-selective antisense oligonucleotides entrapped in anti-GD2 immunoliposome: immune cell-mediated anti-tumor activities
C Brignole, D Marimpietri, G Pagnan, D Di Paolo, M Zancolli, V Pistoia, ...
Cancer letters 228 (1-2), 181-186, 2005
552005
Enhanced anti-tumor and anti-angiogenic efficacy of a novel liposomal fenretinide on human neuroblastoma
D Di Paolo, F Pastorino, G Zuccari, I Caffa, M Loi, D Marimpietri, ...
Journal of controlled release 170 (3), 445-451, 2013
522013
Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings
M Loi, D Di Paolo, M Soster, C Brignole, A Bartolini, L Emionite, J Sun, ...
Journal of controlled release 170 (2), 233-241, 2013
522013
The combined therapeutic effects of bortezomib and fenretinide on neuroblastoma cells involve endoplasmic reticulum stress response
G Pagnan, D Di Paolo, R Carosio, F Pastorino, D Marimpietri, C Brignole, ...
Clinical Cancer Research 15 (4), 1199-1209, 2009
502009
Drug delivery systems: application of liposomal anti-tumor agents to neuroectodermal cancer treatment
D Di Paolo, F Pastorino, C Brignole, D Marimpietri, M Loi, M Ponzoni, ...
Tumori Journal 94 (2), 246-253, 2008
412008
Coated cationic lipid-nanoparticles entrapping miR-660 inhibit tumor growth in patient-derived xenografts lung cancer models
M Moro, D Di Paolo, M Milione, G Centonze, V Bornaghi, C Borzi, ...
Journal of controlled release 308, 44-56, 2019
392019
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