Simon Warby
TitleCited byYear
Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin
RK Graham, Y Deng, EJ Slow, B Haigh, N Bissada, G Lu, J Pearson, ...
Cell 125 (6), 1179-1191, 2006
6272006
Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease
CL Wellington, LM Ellerby, CA Gutekunst, D Rogers, S Warby, ...
Journal of Neuroscience 22 (18), 7862-7872, 2002
3592002
Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in China
F Han, L Lin, SC Warby, J Faraco, J Li, SX Dong, P An, L Zhao, LH Wang, ...
Annals of neurology 70 (3), 410-417, 2011
3342011
CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion
JM Lee, EM Ramos, JH Lee, T Gillis, JS Mysore, MR Hayden, SC Warby, ...
Neurology 78 (10), 690-695, 2012
2132012
HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis
RR Singaraja, S Hadano, M Metzler, S Givan, CL Wellington, S Warby, ...
Human molecular genetics 11 (23), 2815-2828, 2002
2012002
Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the huntington disease gene/allele-specific silencing of mutant Huntingtin
JB Carroll, SC Warby, AL Southwell, CN Doty, S Greenlee, N Skotte, ...
Molecular Therapy 19 (12), 2178-2185, 2011
1802011
Common variants in P2RY11 are associated with narcolepsy
BR Kornum, M Kawashima, J Faraco, L Lin, TJ Rico, S Hesselson, ...
Nature genetics 43 (1), 66, 2011
1752011
CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup
SC Warby, A Montpetit, AR Hayden, JB Carroll, SL Butland, H Visscher, ...
The American Journal of Human Genetics 84 (3), 351-366, 2009
1692009
Huntingtin interacting protein 1 induces apoptosis via a novel caspase-dependent death effector domain
AS Hackam, AS Yassa, R Singaraja, M Metzler, CA Gutekunst, L Gan, ...
Journal of Biological Chemistry 275 (52), 41299-41308, 2000
1522000
Sleep-spindle detection: crowdsourcing and evaluating performance of experts, non-experts and automated methods
SC Warby, SL Wendt, P Welinder, EGS Munk, O Carrillo, HBD Sorensen, ...
Nature methods 11 (4), 385, 2014
1512014
Huntingtin phosphorylation on serine 421 is significantly reduced in the striatum and by polyglutamine expansion in vivo
SC Warby, EY Chan, M Metzler, L Gan, RR Singaraja, SF Crocker, ...
Human molecular genetics 14 (11), 1569-1577, 2005
1292005
Activated caspase-6 and caspase-6-cleaved fragments of huntingtin specifically colocalize in the nucleus
SC Warby, CN Doty, RK Graham, JB Carroll, YZ Yang, RR Singaraja, ...
Human molecular genetics 17 (15), 2390-2404, 2008
1192008
Predictive testing for Huntington disease: interpretation and significance of intermediate alleles
A Semaka, S Creighton, S Warby, MR Hayden
Clinical genetics 70 (4), 283-294, 2006
1192006
HTT haplotypes contribute to differences in Huntington disease prevalence between Europe and East Asia
SC Warby, H Visscher, JA Collins, CN Doty, C Carter, SL Butland, ...
European Journal of Human Genetics 19 (5), 561, 2011
1122011
Phosphorylation of huntingtin reduces the accumulation of its nuclear fragments
SC Warby, CN Doty, RK Graham, J Shively, RR Singaraja, MR Hayden
Molecular and Cellular Neuroscience 40 (2), 121-127, 2009
842009
Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study
JL Li, MR Hayden, SC Warby, A Durr, PJ Morrison, M Nance, CA Ross, ...
BMC medical genetics 7 (1), 71, 2006
822006
Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patients
NH Skotte, AL Southwell, ME Østergaard, JB Carroll, SC Warby, CN Doty, ...
PloS one 9 (9), e107434, 2014
802014
Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study
DJ Gottlieb, K Hek, T Chen, NF Watson, G Eiriksdottir, EM Byrne, ...
Molecular psychiatry 20 (10), 1232, 2015
682015
Huntington disease
SC Warby, RK Graham, MR Hayden
GeneReviews at GeneTests: Medical Genetics Information Resource (database …, 2010
66*2010
A fully humanized transgenic mouse model of Huntington disease
AL Southwell, SC Warby, JB Carroll, CN Doty, NH Skotte, W Zhang, ...
Human Molecular Genetics 22 (1), 18-34, 2013
572013
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