| Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress AY Shih, DA Johnson, G Wong, AD Kraft, L Jiang, H Erb, JA Johnson, ... Journal of Neuroscience 23 (8), 3394-3406, 2003 | 902 | 2003 |
| Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain AY Shih, JD Driscoll, PJ Drew, N Nishimura, CB Schaffer, D Kleinfeld Journal of Cerebral Blood Flow & Metabolism 32 (7), 1277-1309, 2012 | 515 | 2012 |
| A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo AY Shih, P Li, TH Murphy Journal of Neuroscience 25 (44), 10321-10335, 2005 | 503 | 2005 |
| Chronic optical access through a polished and reinforced thinned skull PJ Drew, AY Shih, JD Driscoll, PM Knutsen, P Blinder, D Davalos, ... Nature methods 7 (12), 981-984, 2010 | 465 | 2010 |
| The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit AY Shih, P Blinder, PS Tsai, B Friedman, G Stanley, PD Lyden, ... Nature neuroscience 16 (1), 55-63, 2013 | 396 | 2013 |
| NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons JM Lee, AY Shih, TH Murphy, JA Johnson Journal of Biological Chemistry 278 (39), 37948-37956, 2003 | 377 | 2003 |
| Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation AY Shih, H Erb, X Sun, S Toda, PW Kalivas, TH Murphy Journal of Neuroscience 26 (41), 10514-10523, 2006 | 373 | 2006 |
| Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice DA Hartmann, RG Underly, RI Grant, AN Watson, V Lindner, AY Shih Neurophotonics 2 (4), 041402-041402, 2015 | 329 | 2015 |
| Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo AY Shih, S Imbeault, V Barakauskas, H Erb, L Jiang, P Li, TH Murphy Journal of Biological Chemistry 280 (24), 22925-22936, 2005 | 321 | 2005 |
| Fluctuating and sensory-induced vasodynamics in rodent cortex extend arteriole capacity PJ Drew, AY Shih, D Kleinfeld Proceedings of the National Academy of Sciences 108 (20), 8473-8478, 2011 | 316 | 2011 |
| Detection, risk factors, and functional consequences of cerebral microinfarcts SJ Van Veluw, AY Shih, EE Smith, C Chen, JA Schneider, JM Wardlaw, ... The Lancet Neurology 16 (9), 730-740, 2017 | 311 | 2017 |
| Brain capillary pericytes exert a substantial but slow influence on blood flow DA Hartmann, AA Berthiaume, RI Grant, SA Harrill, T Koski, T Tieu, ... Nature neuroscience 24 (5), 633-645, 2021 | 293 | 2021 |
| Entrainment of arteriole vasomotor fluctuations by neural activity is a basis of blood-oxygenation-level-dependent “resting-state” connectivity C Mateo, PM Knutsen, PS Tsai, AY Shih, D Kleinfeld Neuron 96 (4), 936-948. e3, 2017 | 285 | 2017 |
| Organizational hierarchy and structural diversity of microvascular pericytes in adult mouse cortex RI Grant, DA Hartmann, RG Underly, AA Berthiaume, NR Bhat, AY Shih Journal of Cerebral Blood Flow & Metabolism 39 (3), 411-425, 2019 | 254 | 2019 |
| Topological basis for the robust distribution of blood to rodent neocortex P Blinder, AY Shih, C Rafie, D Kleinfeld Proceedings of the National Academy of Sciences 107 (28), 12670-12675, 2010 | 215 | 2010 |
| Pericytes as inducers of rapid, matrix metalloproteinase-9-dependent capillary damage during ischemia RG Underly, M Levy, DA Hartmann, RI Grant, AN Watson, AY Shih Journal of Neuroscience 37 (1), 129-140, 2017 | 187 | 2017 |
| Dynamic remodeling of pericytes in vivo maintains capillary coverage in the adult mouse brain AA Berthiaume, RI Grant, KP McDowell, RG Underly, DA Hartmann, ... Cell reports 22 (1), 8-16, 2018 | 183 | 2018 |
| Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke AY Shih, B Friedman, PK Drew, PS Tsai, PD Lyden, D Kleinfeld Journal of Cerebral Blood Flow & Metabolism 29 (4), 738-751, 2009 | 172 | 2009 |
| Rapid determination of particle velocity from space-time images using the Radon transform PJ Drew, P Blinder, G Cauwenberghs, AY Shih, D Kleinfeld Journal of computational neuroscience 29, 5-11, 2010 | 170 | 2010 |
| A polished and reinforced thinned-skull window for long-term imaging of the mouse brain AY Shih, C Mateo, PJ Drew, PS Tsai, D Kleinfeld Journal of visualized experiments: JoVE, 2012 | 150 | 2012 |
David KleinfeldDistinguished Professor of Physics and Neurobiology, UCSDVerified email at physics.ucsd.edu
