The making of a slicer: activation of human Argonaute-1 CR Faehnle, E Elkayam, AD Haase, GJ Hannon, L Joshua-Tor Cell reports 3 (6), 1901-1909, 2013 | 168 | 2013 |
Mechanism of Dis3l2 substrate recognition in the Lin28–let-7 pathway CR Faehnle, J Walleshauser, L Joshua-Tor Nature 514 (7521), 252-256, 2014 | 142 | 2014 |
Argonautes confront new small RNAs CR Faehnle, L Joshua-Tor Current opinion in chemical biology 11 (5), 569-577, 2007 | 125 | 2007 |
PTEN functions by recruitment to cytoplasmic vesicles A Naguib, G Bencze, H Cho, W Zheng, A Tocilj, E Elkayam, CR Faehnle, ... Molecular cell 58 (2), 255-268, 2015 | 105 | 2015 |
Multivalent recruitment of human argonaute by GW182 E Elkayam, CR Faehnle, M Morales, J Sun, H Li, L Joshua-Tor Molecular cell 67 (4), 646-658. e3, 2017 | 102 | 2017 |
Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis CR Faehnle, J Walleshauser, L Joshua-Tor Nature structural & molecular biology 24 (8), 658-665, 2017 | 53 | 2017 |
Examination of key intermediates in the catalytic cycle of aspartate-β-semialdehyde dehydrogenase from a Gram-positive infectious bacteria CR Faehnle, J Le Coq, X Liu, RE Viola Journal of Biological Chemistry 281 (41), 31031-31040, 2006 | 52 | 2006 |
A new branch in the family: structure of aspartate-β-semialdehyde dehydrogenase from Methanococcus jannaschii CR Faehnle, JF Ohren, RE Viola Journal of molecular biology 353 (5), 1055-1068, 2005 | 47 | 2005 |
Purification and preliminary characterization of brain aspartoacylase RA Moore, J Le Coq, CR Faehnle, RE Viola Archives of biochemistry and biophysics 413 (1), 1-8, 2003 | 42 | 2003 |
The initial step in the archaeal aspartate biosynthetic pathway catalyzed by a monofunctional aspartokinase CR Faehnle, X Liu, A Pavlovsky, RE Viola Acta Crystallographica Section F: Structural Biology and Crystallization …, 2006 | 36 | 2006 |
The catalytic machinery of a key enzyme in amino Acid biosynthesis RE Viola, CR Faehnle, J Blanco, RA Moore, X Liu, BT Arachea, ... Journal of amino acids 2011, 2011 | 35 | 2011 |
A rapid method for the purification of methanol dehydrogenase from Methylobacterium extorquens Q Liu, JR Kirchhoff, CR Faehnle, RE Viola, RA Hudson Protein expression and purification 46 (2), 316-320, 2006 | 35 | 2006 |
Critical catalytic functional groups in the mechanism of aspartate-β-semialdehyde dehydrogenase J Blanco, RA Moore, CR Faehnle, RE Viola Acta Crystallographica Section D: Biological Crystallography 60 (10), 1808-1815, 2004 | 30 | 2004 |
Structural characterization of inhibitors with selectivity against members of a homologous enzyme family AG Pavlovsky, X Liu, CR Faehnle, N Potente, RE Viola Chemical biology & drug design 79 (1), 128-136, 2012 | 29 | 2012 |
Argonaute MID domain takes centre stage CR Faehnle, L Joshua‐Tor EMBO reports 11 (8), 564-565, 2010 | 27 | 2010 |
The role of substrate-binding groups in the mechanism of aspartate-β-semialdehyde dehydrogenase J Blanco, RA Moore, CR Faehnle, DM Coe, RE Viola Acta Crystallographica Section D: Biological Crystallography 60 (8), 1388-1395, 2004 | 27 | 2004 |
Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-β-semialdehyde dehydrogenase CR Faehnle, J Blanco, RE Viola Acta Crystallographica Section D: Biological Crystallography 60 (12), 2320-2324, 2004 | 26* | 2004 |
The structure of a redundant enzyme: a second isoform of aspartate β-semialdehyde dehydrogenase in Vibrio cholerae RE Viola, X Liu, JF Ohren, CR Faehnle Acta Crystallographica Section D: Biological Crystallography 64 (3), 321-330, 2008 | 24 | 2008 |
Abstract LB-063: PTEN function is controlled by recruitment to cytoplasmic vesicles A Naguib, G Bencze, H Cho, W Zheng, A Tocilj, E Elkayam, CR Faehnle, ... Cancer Research 75 (15_Supplement), LB-063-LB-063, 2015 | | 2015 |
Upstream activation of PTEN. A Naguib, G Bencze, CR Faehnle, T Schalch, Z Lazar, CI Ruse, ... Cancer Research 73 (8_Supplement), 5156-5156, 2013 | | 2013 |