|Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells|
K Blaschke, KT Ebata, MM Karimi, JA Zepeda-Martínez, P Goyal, ...
Nature 500, 223-226, 2013
|Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET|
T Matsui, D Leung, H Miyashita, IA Maksakova, H Miyachi, H Kimura, ...
Nature 464 (7290), 927, 2010
|Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells|
MC Lorincz, DR Dickerson, M Schmitt, M Groudine
Nature structural & molecular biology 11 (11), 1068, 2004
|DNA methylation and SETDB1/H3K9me3 regulate predominantly distinct sets of genes, retroelements, and chimeric transcripts in mESCs|
MM Karimi, P Goyal, IA Maksakova, M Bilenky, D Leung, JX Tang, ...
Cell stem cell 8 (6), 676-687, 2011
|DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity|
KB Dong, IA Maksakova, F Mohn, D Leung, R Appanah, S Lee, HW Yang, ...
The EMBO journal 27 (20), 2691-2701, 2008
|Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells|
J Wang, G Xie, M Singh, AT Ghanbarian, T Raskó, A Szvetnik, H Cai, ...
Nature 516 (7531), 405, 2014
|Genomic targeting of methylated DNA: influence of methylation on transcription, replication, chromatin structure, and histone acetylation|
D Schübeler, MC Lorincz, DM Cimbora, A Telling, YQ Feng, ...
Molecular and cellular biology 20 (24), 9103-9112, 2000
|Simultaneous fluorescence-activated cell sorter analysis of two distinct transcriptional elements within a single cell using engineered green fluorescent proteins|
MT Anderson, IM Tjioe, MC Lorincz, DR Parks, LA Herzenberg, GP Nolan
Proceedings of the National Academy of Sciences 93 (16), 8508-8511, 1996
|Dynamic analysis of proviral induction and de novo methylation: implications for a histone deacetylase-independent, methylation density-dependent mechanism of transcriptional …|
MC Lorincz, D Schübeler, SC Goeke, M Walters, M Groudine, DIK Martin
Molecular and cellular biology 20 (3), 842-850, 2000
|An ultra-low-input native ChIP-seq protocol for genome-wide profiling of rare cell populations|
J Brind’Amour, S Liu, M Hudson, C Chen, MM Karimi, MC Lorincz
Nature communications 6, 6033, 2015
|DNA methylation density influences the stability of an epigenetic imprint and Dnmt3a/b-independent de novo methylation|
MC Lorincz, D Schübeler, SR Hutchinson, DR Dickerson, M Groudine
Molecular and cellular biology 22 (21), 7572-7580, 2002
|Methylation-mediated proviral silencing is associated with MeCP2 recruitment and localized histone H3 deacetylation|
MC Lorincz, D Schübeler, M Groudine
Molecular and cellular biology 21 (23), 7913-7922, 2001
|Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells|
S Liu, J Brind’Amour, MM Karimi, K Shirane, A Bogutz, L Lefebvre, ...
Genes & development 28 (18), 2041-2055, 2014
|Silencing of endogenous retroviruses: when and why do histone marks predominate?|
DC Leung, MC Lorincz
Trends in biochemical sciences 37 (4), 127-133, 2012
|Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing|
DC Leung, KB Dong, IA Maksakova, P Goyal, R Appanah, S Lee, ...
Proceedings of the National Academy of Sciences 108 (14), 5718-5723, 2011
|Position effects are influenced by the orientation of a transgene with respect to flanking chromatin|
YQ Feng, MC Lorincz, S Fiering, JM Greally, EE Bouhassira
Molecular and cellular biology 21 (1), 298-309, 2001
|Retrotransposon-induced heterochromatin spreading in the mouse revealed by insertional polymorphisms|
R Rebollo, MM Karimi, M Bilenky, L Gagnier, K Miceli-Royer, Y Zhang, ...
PLoS genetics 7 (9), e1002301, 2011
|Long terminal repeats: from parasitic elements to building blocks of the transcriptional regulatory repertoire|
PJ Thompson, TS Macfarlan, MC Lorincz
Molecular cell 62 (5), 766-776, 2016
|An unmethylated 3′ promoter-proximal region is required for efficient transcription initiation|
R Appanah, DR Dickerson, P Goyal, M Groudine, MC Lorincz
PLoS genetics 3 (2), e27, 2007
|Targeting of EZH2 to a defined genomic site is sufficient for recruitment of Dnmt3a but not de novo DNA methylation|
M Rush, R Appanah, S Lee, LL Lam, P Goyal, MC Lorincz
Epigenetics 4 (6), 404-414, 2009