Genomewide association study of tacrolimus concentrations in African American kidney transplant recipients identifies multiple CYP3A5 alleles WS Oetting, DP Schladt, W Guan, MB Miller, RP Remmel, C Dorr, ... American Journal of Transplantation 16 (2), 574-582, 2016 | 128 | 2016 |
Transposon mutagenesis screen identifies potential lung cancer drivers and CUL3 as a tumor suppressor C Dorr, C Janik, M Weg, RA Been, J Bader, R Kang, B Ng, L Foran, ... Molecular Cancer Research 13 (8), 1238-1247, 2015 | 50 | 2015 |
Tacrolimus troughs and genetic determinants of metabolism in kidney transplant recipients: A comparison of four ancestry groups ME Mohamed, DP Schladt, W Guan, B Wu, J van Setten, BJ Keating, ... American Journal of Transplantation 19 (10), 2795-2804, 2019 | 42 | 2019 |
Tacrolimus trough and dose intra‐patient variability and CYP3A5 genotype: Effects on acute rejection and graft failure in European American and African American kidney … SR Seibert, DP Schladt, B Wu, W Guan, C Dorr, RP Remmel, AJ Matas, ... Clinical transplantation 32 (12), e13424, 2018 | 40 | 2018 |
Genetics of acute rejection after kidney transplantation CR Dorr, WS Oetting, PA Jacobson, AK Israni Transplant International 31 (3), 263-277, 2018 | 35 | 2018 |
Triterpene derivatives that inhibit human immunodeficiency virus type 1 replication CR Dorr, S Yemets, O Kolomitsyna, P Krasutsky, LM Mansky Bioorganic & medicinal chemistry letters 21 (1), 542-545, 2011 | 35 | 2011 |
Differentially expressed gene transcripts using RNA sequencing from the blood of immunosuppressed kidney allograft recipients C Dorr, B Wu, W Guan, A Muthusamy, K Sanghavi, DP Schladt, ... PloS one 10 (5), e0125045, 2015 | 31 | 2015 |
Attempted validation of 44 reported SNPs associated with tacrolimus troughs in a cohort of kidney allograft recipients WS Oetting, B Wu, DP Schladt, W Guan, RP Remmel, C Dorr, RB Mannon, ... Pharmacogenomics 19 (3), 175-184, 2018 | 29 | 2018 |
CRISPR/Cas9 genetic modification of CYP3A5* 3 in HuH-7 human hepatocyte cell line leads to cell lines with increased midazolam and tacrolimus metabolism CR Dorr, RP Remmel, A Muthusamy, J Fisher, BS Moriarity, K Yasuda, ... Drug Metabolism and Disposition 45 (8), 957-965, 2017 | 25 | 2017 |
Genetic variants associated with immunosuppressant pharmacokinetics and adverse effects in the DeKAF genomics genome-wide association studies WS Oetting, B Wu, DP Schladt, W Guan, J Van Setten, BJ Keating, D Iklé, ... Transplantation 103 (6), 1131-1139, 2019 | 18 | 2019 |
Tacrolimus Elimination in Four Patients With a CYP3A5*3/*3 CYP3A4*22/*22 Genotype Combination A Scheibner, R Remmel, D Schladt, WS Oetting, W Guan, B Wu, C Dorr, ... Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 38 (7 …, 2018 | 18 | 2018 |
Identification of genetic variants associated with tacrolimus metabolism in kidney transplant recipients by extreme phenotype sampling and next generation sequencing CR Dorr, B Wu, RP Remmel, A Muthusamy, DP Schladt, JE Abrahante, ... The pharmacogenomics journal 19 (4), 375-389, 2019 | 17 | 2019 |
Analysis of 75 candidate SNPs associated with acute rejection in kidney transplant recipients: validation of rs2910164 in microRNA MIR146A WS Oetting, DP Schladt, CR Dorr, B Wu, W Guan, RP Remmel, D Iklé, ... Transplantation 103 (8), 1591-1602, 2019 | 15 | 2019 |
Deceased-donor apolipoprotein L1 renal-risk variants have minimal effects on liver transplant outcomes CR Dorr, BI Freedman, PJ Hicks, WM Brown, GB Russell, BA Julian, ... PloS one 11 (4), e0152775, 2016 | 12 | 2016 |
DeKAF Genomics and GEN03 Investigators. Tacrolimus troughs and genetic determinants of metabolism in kidney transplant recipients: A comparison of four ancestry groups ME Mohamed, DP Schladt, W Guan, B Wu, J van Setten, BJ Keating, ... Am. J. Transplant 19, 2795-2804, 2019 | 8 | 2019 |
Pharmacogenomics in kidney transplant recipients and potential for integration into practice TT Nguyen, RA Pearson, ME Mohamed, DP Schladt, D Berglund, Z Rivers, ... Journal of clinical pharmacy and therapeutics 45 (6), 1457-1465, 2020 | 7 | 2020 |
Precision dosing for tacrolimus using genotypes and clinical factors in kidney transplant recipients of european ancestry M Al‐Kofahi, WS Oetting, DP Schladt, RP Remmel, W Guan, B Wu, ... The Journal of Clinical Pharmacology 61 (8), 1035-1044, 2021 | 5 | 2021 |
DeKAF Genomics and GEN-03 Investigators. Genetic variants associated with immunosuppressant pharmacokinetics and adverse effects in the DeKAF genomics genome-wide association … WS Oetting, B Wu, DP Schladt, W Guan, J van Setten, BJ Keating, D Iklé, ... Transplantation 103 (6), 1131-1139, 2019 | 5 | 2019 |
DeKAF Genomics and GEN03 Investigators. Analysis of 75 candidate SNPs associated with acute rejection in kidney transplant recipients: validation of rs2910164 in microRNA MIR146A WS Oetting, DP Schladt, CR Dorr, B Wu, W Guan, RP Remmel, D Ikle, ... Transplantation 103 (8), 1591-1602, 2019 | 5 | 2019 |
Concepts of genomics in kidney transplantation WS Oetting, C Dorr, RP Remmel, AJ Matas, AK Israni, PA Jacobson Current transplantation reports 4, 116-123, 2017 | 5 | 2017 |