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Robert C. Doebele, MD, PhD
Robert C. Doebele, MD, PhD
University of Colorado, Anschutz Medical Campus
Verified email at cuanschutz.edu - Homepage
Title
Cited by
Cited by
Year
Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children
A Drilon, TW Laetsch, S Kummar, SG DuBois, UN Lassen, GD Demetri, ...
New England Journal of Medicine 378 (8), 731-739, 2018
24712018
Crizotinib in ROS1-rearranged non–small-cell lung cancer
AT Shaw, SHI Ou, YJ Bang, DR Camidge, BJ Solomon, R Salgia, GJ Riely, ...
New England Journal of Medicine 371 (21), 1963-1971, 2014
21162014
Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1–2 trials
RC Doebele, A Drilon, L Paz-Ares, S Siena, AT Shaw, AF Farago, ...
The Lancet Oncology 21 (2), 271-282, 2020
13472020
Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non–small cell lung cancer
RC Doebele, AB Pilling, DL Aisner, TG Kutateladze, AT Le, AJ Weickhardt, ...
Clinical cancer research 18 (5), 1472-1482, 2012
12682012
Non–small cell lung cancer, version 5.2017, NCCN clinical practice guidelines in oncology
DS Ettinger, DE Wood, DL Aisner, W Akerley, J Bauman, LR Chirieac, ...
Journal of the National Comprehensive Cancer Network 15 (4), 504-535, 2017
11812017
Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis
AT Shaw, BY Yeap, BJ Solomon, GJ Riely, J Gainor, JA Engelman, ...
The lancet oncology 12 (11), 1004-1012, 2011
11352011
Local consolidative therapy vs. maintenance therapy or observation for patients with oligometastatic non–small-cell lung cancer: long-term results of a multi-institutional …
DR Gomez, C Tang, J Zhang, GR Blumenschein Jr, M Hernandez, JJ Lee, ...
Journal of Clinical Oncology 37 (18), 1558, 2019
10092019
Local consolidative therapy versus maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer without progression after first-line systemic …
DR Gomez, GR Blumenschein, JJ Lee, M Hernandez, R Ye, DR Camidge, ...
The lancet oncology 17 (12), 1672-1682, 2016
10072016
Rociletinib in EGFR-mutated non–small-cell lung cancer
LV Sequist, JC Soria, JW Goldman, HA Wakelee, SM Gadgeel, A Varga, ...
New England Journal of Medicine 372 (18), 1700-1709, 2015
8172015
Safety and antitumor activity of the multitargeted pan-TRK, ROS1, and ALK inhibitor entrectinib: combined results from two phase I trials (ALKA-372-001 and STARTRK-1)
A Drilon, S Siena, SHI Ou, M Patel, MJ Ahn, J Lee, TM Bauer, AF Farago, ...
Cancer discovery 7 (4), 400-409, 2017
7692017
Local ablative therapy of oligoprogressive disease prolongs disease control by tyrosine kinase inhibitors in oncogene-addicted non–small-cell lung cancer
AJ Weickhardt, B Scheier, JM Burke, G Gan, X Lu, PA Bunn Jr, DL Aisner, ...
Journal of Thoracic Oncology 7 (12), 1807-1814, 2012
6882012
Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer
A Vaishnavi, M Capelletti, AT Le, S Kako, M Butaney, D Ercan, S Mahale, ...
Nature medicine 19 (11), 1469-1472, 2013
6842013
TRKing down an old oncogene in a new era of targeted therapy
A Vaishnavi, AT Le, RC Doebele
Cancer discovery 5 (1), 25-34, 2015
640*2015
Identifying and Targeting ROS1 Gene Fusions in Non–Small Cell Lung Cancer
KD Davies, AT Le, MF Theodoro, MC Skokan, DL Aisner, EM Berge, ...
Clinical Cancer Research 18 (17), 4570-4579, 2012
5232012
Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers
CM Blakely, TBK Watkins, W Wu, B Gini, JJ Chabon, CE McCoach, ...
Nature genetics 49 (12), 1693-1704, 2017
4822017
Mechanisms and clinical activity of an EGFR and HER2 exon 20–selective kinase inhibitor in non–small cell lung cancer
JP Robichaux, YY Elamin, Z Tan, BW Carter, S Zhang, S Liu, S Li, T Chen, ...
Nature medicine 24 (5), 638-646, 2018
4362018
Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment
DR Camidge, SA Kono, A Flacco, AC Tan, RC Doebele, Q Zhou, L Crino, ...
Clinical Cancer Research 16 (22), 5581-5590, 2010
4252010
An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101
RC Doebele, LE Davis, A Vaishnavi, AT Le, A Estrada-Bernal, S Keysar, ...
Cancer discovery 5 (10), 1049-1057, 2015
410*2015
Therapy-induced evolution of human lung cancer revealed by single-cell RNA sequencing
A Maynard, CE McCoach, JK Rotow, L Harris, F Haderk, DL Kerr, ...
Cell 182 (5), 1232-1251. e22, 2020
4082020
Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1–2 trials
A Drilon, S Siena, R Dziadziuszko, F Barlesi, MG Krebs, AT Shaw, ...
The Lancet Oncology 21 (2), 261-270, 2020
4052020
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