| Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin O Kovalchuk, J Filkowski, J Meservy, Y Ilnytskyy, VP Tryndyak, ... Molecular cancer therapeutics 7 (7), 2152-2159, 2008 | 790 | 2008 |
| Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond L Luzhna, P Kathiria, O Kovalchuk Frontiers in genetics 4, 131, 2013 | 463 | 2013 |
| Alterations of microRNAs and their targets are associated with acquired resistance of MCF‐7 breast cancer cells to cisplatin IP Pogribny, JN Filkowski, VP Tryndyak, A Golubov, SI Shpyleva, ... International journal of cancer 127 (8), 1785-1794, 2010 | 408 | 2010 |
| Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location C Yauk, A Polyzos, A Rowan-Carroll, CM Somers, RW Godschalk, ... Proceedings of the National Academy of Sciences 105 (2), 605-610, 2008 | 336 | 2008 |
| Pathogen-induced systemic plant signal triggers DNA rearrangements I Kovalchuk, O Kovalchuk, V Kalck, V Boyko, J Filkowski, M Heinlein, ... Nature 423 (6941), 760-762, 2003 | 303 | 2003 |
| DNA double-strand breaks form in bystander cells after microbeam irradiation of three-dimensional human tissue models OA Sedelnikova, A Nakamura, O Kovalchuk, I Koturbash, SA Mitchell, ... Cancer research 67 (9), 4295-4302, 2007 | 277 | 2007 |
| Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo I Koturbash, RE Rugo, CA Hendricks, J Loree, B Thibault, K Kutanzi, ... Oncogene 25 (31), 4267-4275, 2006 | 261 | 2006 |
| Genome hypermethylation in Pinus silvestris of Chernobyl—a mechanism for radiation adaptation? O Kovalchuk, P Burke, A Arkhipov, N Kuchma, SJ James, I Kovalchuk, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 529 (1 …, 2003 | 253 | 2003 |
| Role of epigenetic effectors in maintenance of the long-term persistent bystander effect in spleen in vivo I Koturbash, A Boyko, R Rodriguez-Juarez, RJ McDonald, VP Tryndyak, ... Carcinogenesis 28 (8), 1831-1838, 2007 | 241 | 2007 |
| Dose-dependence, sex-and tissue-specificity, and persistence of radiation-induced genomic DNA methylation changes I Pogribny, J Raiche, M Slovack, O Kovalchuk Biochemical and biophysical research communications 320 (4), 1253-1261, 2004 | 229 | 2004 |
| Molecular aspects of plant adaptation to life in the Chernobyl zone I Kovalchuk, V Abramov, I Pogribny, O Kovalchuk Plant Physiology 135 (1), 357-363, 2004 | 223 | 2004 |
| Role of ferritin alterations in human breast cancer cells SI Shpyleva, VP Tryndyak, O Kovalchuk, A Starlard-Davenport, ... Breast cancer research and treatment 126, 63-71, 2011 | 221 | 2011 |
| Fractionated low-dose radiation exposure leads to accumulation of DNA damage and profound alterations in DNA and histone methylation in the murine thymus I Pogribny, I Koturbash, V Tryndyak, D Hudson, SML Stevenson, ... Molecular cancer research 3 (10), 553-561, 2005 | 211 | 2005 |
| Maternal stress induces epigenetic signatures of psychiatric and neurological diseases in the offspring FCR Zucchi, Y Yao, ID Ward, Y Ilnytskyy, DM Olson, K Benzies, ... PloS one 8 (2), e56967, 2013 | 210 | 2013 |
| Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 … VP Tryndyak, O Kovalchuk, IP Pogribny Cancer biology & therapy 5 (1), 65-70, 2006 | 180 | 2006 |
| The Allium cepa chromosome aberration test reliably measures genotoxicity of soils of inhabited areas in the Ukraine contaminated by the Chernobyl accident O Kovalchuk, I Kovalchuk, A Arkhipov, P Telyuk, B Hohn, L Kovalchuk Mutation Research/Genetic Toxicology and Environmental Mutagenesis 415 (1-2 …, 1998 | 174 | 1998 |
| A sensitive transgenic plant system to detect toxic inorganic compounds in the environment O Kovalchuk, V Titov, B Hohn, I Kovalchuk nature biotechnology 19 (6), 568-572, 2001 | 172 | 2001 |
| Induction of microRNAome deregulation in rat liver by long-term tamoxifen exposure IP Pogribny, VP Tryndyak, A Boyko, R Rodriguez-Juarez, FA Beland, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 619 (1 …, 2007 | 171 | 2007 |
| Genome-wide variation of the somatic mutation frequency in transgenic plants I Kovalchuk, O Kovalchuk, B Hohn The EMBO journal 19 (17), 4431-4438, 2000 | 171 | 2000 |
| Epigenetic changes and nontargeted radiation effects—is there a link? O Kovalchuk, JE Baulch Environmental and molecular mutagenesis 49 (1), 16-25, 2008 | 170 | 2008 |
Igor KovalchukProfessor, University of LethbridgeVerified email at uleth.ca
