Christof Fellmann
Christof Fellmann
Verified email at gladstone.ucsf.edu
TitleCited byYear
An optimized microRNA backbone for effective single-copy RNAi
C Fellmann, T Hoffmann, V Sridhar, B Hopfgartner, M Muhar, M Roth, ...
Cell reports 5 (6), 1704-1713, 2013
2792013
Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi
J Zuber, K McJunkin, C Fellmann, LE Dow, MJ Taylor, GJ Hannon, ...
Nature biotechnology 29 (1), 79-83, 2011
2022011
An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance
J Zuber, AR Rappaport, W Luo, E Wang, C Chen, AV Vaseva, J Shi, ...
Genes & development 25 (15), 1628-1640, 2011
1992011
Functional identification of optimized RNAi triggers using a massively parallel sensor assay
C Fellmann, J Zuber, K McJunkin, K Chang, CD Malone, RA Dickins, Q Xu, ...
Molecular cell 41 (6), 733-746, 2011
1922011
HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase
A Sendoel, I Kohler, C Fellmann, SW Lowe, MO Hengartner
Nature 465 (7298), 577-583, 2010
1892010
Stable RNA interference rules for silencing
C Fellmann, SW Lowe
Nature cell biology 16 (1), 10-18, 2014
1622014
Cornerstones of CRISPR-Cas in drug discovery and therapy
C Fellmann, BG Gowen, PC Lin, JA Doudna, JE Corn
Nature Reviews Drug Discovery 16 (2), 89-100, 2017
1602017
Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors
P Lito, A Saborowski, J Yue, M Solomon, E Joseph, S Gadal, ...
Cancer Cell 25 (5), 697-710, 2014
1382014
A pipeline for the generation of shRNA transgenic mice
LE Dow, PK Premsrirut, J Zuber, C Fellmann, K McJunkin, C Miething, ...
Nature protocols 7 (2), 374-393, 2012
1202012
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
BL Oakes, DC Nadler, A Flamholz, C Fellmann, BT Staahl, JA Doudna, ...
Nature biotechnology 34 (6), 646-651, 2016
952016
Development of siRNA payloads to target KRAS-mutant cancer
TL Yuan, C Fellmann, CS Lee, CD Ritchie, V Thapar, LC Lee, DJ Hsu, ...
Cancer discovery 4 (10), 1182-1197, 2014
642014
A Computational Algorithm to Predict shRNA Potency
SRV Knott, AR Maceli, N Erard, K Chang, K Marran, X Zhou, A Gordon, ...
Molecular cell 56 (6), 796-807, 2014
502014
Systematic discovery of natural CRISPR-Cas12a inhibitors
KE Watters, C Fellmann, HB Bai, SM Ren, JA Doudna
Science 362 (6411), 236-239, 2018
432018
Translation initiation factor eIF4F modifies the dexamethasone response in multiple myeloma
F Robert, W Roman, A Bramoullé, C Fellmann, A Roulston, C Shustik, ...
Proceedings of the National Academy of Sciences 111 (37), 13421-13426, 2014
342014
MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2
DG Nowak, H Cho, T Herzka, K Watrud, DV DeMarco, VMY Wang, ...
Cancer discovery 5 (6), 636-651, 2015
312015
Tiling genomes of pathogenic viruses identifies potent antiviral shRNAs and reveals a role for secondary structure in shRNA efficacy
X Tan, ZJ Lu, G Gao, Q Xu, L Hu, C Fellmann, MZ Li, H Qu, SW Lowe, ...
Proceedings of the National Academy of Sciences 109 (3), 869-874, 2012
282012
Differential Effector Engagement by Oncogenic KRAS
TL Yuan, A Amzallag, R Bagni, M Yi, S Afghani, W Burgan, N Fer, ...
Cell Reports 22 (7), 1889-1902, 2018
232018
Prediction of potent shRNAs with a sequential classification algorithm
R Pelossof, L Fairchild, CH Huang, C Widmer, VT Sreedharan, N Sinha, ...
Nature Biotechnology 35 (4), 350-353, 2017
232017
Disruption of the β1L isoform of GABP reverses glioblastoma replicative immortality in a TERT promoter mutation-dependent manner
A Mancini, A Xavier-Magalhães, WS Woods, KT Nguyen, AM Amen, ...
Cancer Cell 34 (3), 513-528. e8, 2018
172018
Extension of the crRNA enhances Cpf1 gene editing in vitro and in vivo
HM Park, H Liu, J Wu, A Chong, V Mackley, C Fellmann, A Rao, F Jiang, ...
Nature Communications 9 (1), 3313, 2018
132018
The system can't perform the operation now. Try again later.
Articles 1–20