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Channing J. Der
Channing J. Der
Adresse e-mail validée de med.unc.edu
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
107082021
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
PJ Roberts, CJ Der
Oncogene 26 (22), 3291-3310, 2007
34512007
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
DJ Klionsky, H Abeliovich, P Agostinis, DK Agrawal, G Aliev, DS Askew, ...
Autophagy 4 (2), 151-175, 2008
27022008
GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors
KL Rossman, CJ Der, J Sondek
Nature reviews Molecular cell biology 6 (2), 167-180, 2005
21352005
The Ras superfamily at a glance
K Wennerberg, KL Rossman, CJ Der
Journal of cell science 118 (5), 843-846, 2005
20612005
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
K Irani, Y Xia, JL Zweier, SJ Sollott, CJ Der, ER Fearon, M Sundaresan, ...
Science 275 (5306), 1649-1652, 1997
20191997
Drugging the undruggable RAS: Mission possible?
AD Cox, SW Fesik, AC Kimmelman, J Luo, CJ Der
Nature reviews Drug discovery 13 (11), 828-851, 2014
19702014
Increasing complexity of Ras signaling
SL Campbell, R Khosravi-Far, KL Rossman, GJ Clark, CJ Der
Oncogene 17 (11), 1395-1413, 1998
14611998
p21ras is modified by a farnesyl isoprenoid.
PJ Casey, PA Solski, CJ Der, JE Buss
Proceedings of the National Academy of Sciences 86 (21), 8323-8327, 1989
12121989
Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses.
CJ Der, TG Krontiris, GM Cooper
Proceedings of the National Academy of Sciences 79 (11), 3637-3640, 1982
11491982
Understanding Ras:‘it ain’t over’til it’s over’
JM Shields, K Pruitt, A McFall, A Shaub, CJ Der
Trends in cell biology 10 (4), 147-154, 2000
10862000
Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?
D Vigil, J Cherfils, KL Rossman, CJ Der
Nature Reviews Cancer 10 (12), 842-857, 2010
9492010
RAS isoforms and mutations in cancer at a glance
GA Hobbs, CJ Der, KL Rossman
Journal of cell science 129 (7), 1287-1292, 2016
9232016
Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI (3) K
PJ Keely, JK Westwick, IP Whitehead, CJ Der, LV Parise
Nature 390 (6660), 632-636, 1997
9201997
Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation
R Khosravi-Far, PA Solski, GJ Clark, MS Kinch, CJ Der
Molecular and cellular biology, 1995
9121995
BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein
AM Pendergast, LA Quilliam, LD Cripe, CH Bassing, Z Dai, N Li, A Batzer, ...
Cell 75 (1), 175-185, 1993
9011993
Rho-family GTPases: it's not only Rac and Rho (and I like it)
K Wennerberg, CJ Der
Journal of cell science 117 (8), 1301-1312, 2004
8562004
Ras history: The saga continues
AD Cox, CJ Der
Small GTPases 1 (1), 2-27, 2010
8472010
Increasing complexity of the Ras signaling pathway
AB Vojtek, CJ Der
Journal of Biological Chemistry 273 (32), 19925-19928, 1998
8061998
KRAS: feeding pancreatic cancer proliferation
KL Bryant, JD Mancias, AC Kimmelman, CJ Der
Trends in biochemical sciences 39 (2), 91-100, 2014
7612014
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