Targeting KRAS mutant cancers with a covalent G12C-specific inhibitor MR Janes, J Zhang, LS Li, R Hansen, U Peters, X Guo, Y Chen, A Babbar, ... Cell 172 (3), 578-589. e17, 2018 | 982 | 2018 |
Selective inhibition of oncogenic KRAS output with small molecules targeting the inactive state MP Patricelli, MR Janes, LS Li, R Hansen, U Peters, LV Kessler, Y Chen, ... Cancer discovery 6 (3), 316-329, 2016 | 693 | 2016 |
Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism P Lito, M Solomon, LS Li, R Hansen, N Rosen Science 351 (6273), 604-608, 2016 | 615 | 2016 |
Metabolite extraction from suspension-cultured mammalian cells for global metabolite profiling CA Sellick, R Hansen, GM Stephens, R Goodacre, AJ Dickson Nature protocols 6 (8), 1241-1249, 2011 | 228 | 2011 |
Effective quenching processes for physiologically valid metabolite profiling of suspension cultured mammalian cells CA Sellick, R Hansen, AR Maqsood, WB Dunn, GM Stephens, ... Analytical chemistry 81 (1), 174-183, 2009 | 176 | 2009 |
The reactivity-driven biochemical mechanism of covalent KRASG12C inhibitors R Hansen, U Peters, A Babbar, Y Chen, J Feng, MR Janes, LS Li, P Ren, ... Nature structural & molecular biology 25 (6), 454-462, 2018 | 117 | 2018 |
Separation and identification of hen egg protein isoforms using SDS–PAGE and 2D gel electrophoresis with MALDI-TOF mass spectrometry V Raikos, R Hansen, L Campbell, SR Euston Food chemistry 99 (4), 702-710, 2006 | 110 | 2006 |
A novel bacteriocin-like substance (BLIS) from a pathogenic strain of Vibrio harveyi S Prasad, PC Morris, R Hansen, PG Meaden, B Austin Microbiology 151 (9), 3051-3058, 2005 | 91 | 2005 |
A dispensable paralog of succinate dehydrogenase subunit C mediates standing resistance towards a subclass of SDHI fungicides in Zymoseptoria tritici D Steinhauer, M Salat, R Frey, A Mosbach, T Luksch, D Balmer, ... PLoS pathogens 15 (12), e1007780, 2019 | 72 | 2019 |
Proteomic analysis of rainbow trout (Oncorhynchus mykiss, Walbaum) serum after administration of probiotics in diets J Brunt, R Hansen, DJ Jamieson, B Austin Veterinary immunology and immunopathology 121 (3-4), 199-205, 2008 | 65 | 2008 |
Phosphoproteomic analysis of protein kinase C signaling in Saccharomyces cerevisiae reveals Slt2 mitogen-activated protein kinase (MAPK)-dependent phosphorylation of eisosome … V Mascaraque, ML Hernaez, M Jimenez-Sanchez, R Hansen, C Gil, ... Molecular & Cellular Proteomics 12 (3), 557-574, 2013 | 64 | 2013 |
Comparison of targeted peptide quantification assays for reductive dehalogenases by selective reaction monitoring (SRM) and precursor reaction monitoring (PRM) C Schiffmann, R Hansen, S Baumann, A Kublik, PH Nielsen, L Adrian, ... Analytical and bioanalytical chemistry 406, 283-291, 2014 | 63 | 2014 |
Rapid monitoring of recombinant antibody production by mammalian cell cultures using Fourier transform infrared spectroscopy and chemometrics CA Sellick, R Hansen, RM Jarvis, AR Maqsood, GM Stephens, ... Biotechnology and bioengineering 106 (3), 432-442, 2010 | 61 | 2010 |
Biochemical foundations of health and energy conservation in hibernating free-ranging subadult brown bear Ursus arctos KG Welinder, R Hansen, MT Overgaard, M Brohus, M Sønderkær, ... Journal of Biological Chemistry 291 (43), 22509-22523, 2016 | 42 | 2016 |
Proteome profile and proteogenomics of the organohalide-respiring bacterium Dehalococcoides mccartyi strain CBDB1 grown on hexachlorobenzene as electron acceptor CL Schiffmann, N Jehmlich, W Otto, R Hansen, PH Nielsen, L Adrian, ... Journal of Proteomics 98, 59-64, 2014 | 35 | 2014 |
Recovery and characterization of a 30.7-kDa protein from Bacillus licheniformis associated with inhibitory activity against methicillin-resistant Staphylococcus aureus … MT Jamal, PC Morris, R Hansen, DJ Jamieson, JG Burgess, B Austin Marine Biotechnology 8, 587-592, 2006 | 35 | 2006 |
Proteomic analysis of a distilling strain of Saccharomyces cerevisiae during industrial grain fermentation R Hansen, SY Pearson, JM Brosnan, PG Meaden, DJ Jamieson Applied microbiology and biotechnology 72, 116-125, 2006 | 31 | 2006 |
Rapid characterization of N‐linked glycans from secreted and gel‐purified monoclonal antibodies using MALDI‐ToF mass spectrometry R Hansen, AJ Dickson, R Goodacre, GM Stephens, CA Sellick Biotechnology and bioengineering 107 (5), 902-908, 2010 | 23 | 2010 |
Activity of recombinant GST in Escherichia coli grown on glucose and glycerol R Hansen, NT Eriksen Process Biochemistry 42 (8), 1259-1263, 2007 | 20 | 2007 |
KO-947, a potent ERK inhibitor with robust preclinical single agent activity in MAPK pathway dysregulated tumors F Burrows, L Kessler, J Chen, X Gao, R Hnsen, S Li, C Thach, L Darjania, ... Cancer Res 77, 5168, 2017 | 17 | 2017 |