| Fasting and cancer: molecular mechanisms and clinical application A Nencioni, I Caffa, S Cortellino, VD Longo Nature Reviews Cancer 18 (11), 707-719, 2018 | 424 | 2018 |
| Fasting-mimicking diet and hormone therapy induce breast cancer regression I Caffa, V Spagnolo, C Vernieri, F Valdemarin, P Becherini, M Wei, ... Nature 583 (7817), 620-624, 2020 | 229 | 2020 |
| The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses I Bauer, A Grozio, D Lasigliè, G Basile, L Sturla, M Magnone, G Sociali, ... Journal of Biological Chemistry 287 (49), 40924-40937, 2012 | 184 | 2012 |
| CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells A Grozio, G Sociali, L Sturla, I Caffa, D Soncini, A Salis, N Raffaelli, ... Journal of Biological Chemistry 288 (36), 25938-25949, 2013 | 163 | 2013 |
| Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer DN Brown, I Caffa, G Cirmena, D Piras, A Garuti, M Gallo, S Alberti, ... Scientific reports 6 (1), 19435, 2016 | 131 | 2016 |
| Regulation and function of extracellular nicotinamide phosphoribosyltransferase/visfatin F Carbone, L Liberale, A Bonaventura, A Vecchiè, M Casula, M Cea, ... Comprehensive Physiology 7 (2), 603-621, 2011 | 109 | 2011 |
| Nutrients in the Prevention of Alzheimer’s Disease AL Cremonini, I Caffa, M Cea, A Nencioni, P Odetti, F Monacelli Oxidative medicine and cellular longevity 2019, 2019 | 103 | 2019 |
| Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers M Di Tano, F Raucci, C Vernieri, I Caffa, R Buono, M Fanti, S Brandhorst, ... Nature Communications 11 (1), 2332, 2020 | 101 | 2020 |
| Nicotinic acid phosphoribosyltransferase regulates cancer cell metabolism, susceptibility to NAMPT inhibitors, and DNA repair F Piacente, I Caffa, S Ravera, G Sociali, M Passalacqua, VG Vellone, ... Cancer research 77 (14), 3857-3869, 2017 | 98 | 2017 |
| Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition I Caffa, V D'Agostino, P Damonte, D Soncini, M Cea, F Monacelli, P Odetti, ... Oncotarget 6 (14), 11820, 2015 | 94 | 2015 |
| Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma M Loi, S Marchiò, P Becherini, D Di Paolo, M Soster, F Curnis, C Brignole, ... Journal of controlled release 145 (1), 66-73, 2010 | 90 | 2010 |
| Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells M Cea, D Soncini, F Fruscione, L Raffaghello, A Garuti, L Emionite, ... PloS one 6 (7), e22739, 2011 | 87 | 2011 |
| Therapeutic targeting of TLR9 inhibits cell growth and induces apoptosis in neuroblastoma C Brignole, D Marimpietri, DD Paolo, P Perri, F Morandi, F Pastorino, ... Cancer research 70 (23), 9816-9826, 2010 | 86 | 2010 |
| Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity D Soncini, I Caffa, G Zoppoli, M Cea, A Cagnetta, M Passalacqua, ... Journal of Biological Chemistry 289 (49), 34189-34204, 2014 | 75 | 2014 |
| Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model G Sociali, M Magnone, S Ravera, P Damonte, T Vigliarolo, M Von Holtey, ... The FASEB Journal 31 (7), 3138, 2017 | 73 | 2017 |
| PHOX2B-Mediated Regulation of ALK Expression: In Vitro Identification of a Functional Relationship between Two Genes Involved in Neuroblastoma T Bachetti, D Di Paolo, S Di Lascio, V Mirisola, C Brignole, M Bellotti, ... PloS one 5 (10), e13108, 2010 | 70 | 2010 |
| Enhanced anti-tumor activity of a new curcumin-related compound against melanoma and neuroblastoma cells M Pisano, G Pagnan, MA Dettori, S Cossu, I Caffa, I Sassu, L Emionite, ... Molecular Cancer 9, 1-12, 2010 | 69 | 2010 |
| Dendritic cells direct circadian anti-tumour immune responses C Wang, C Barnoud, M Cenerenti, M Sun, I Caffa, B Kizil, R Bill, Y Liu, ... Nature 614 (7946), 136-143, 2023 | 67 | 2023 |
| Treatment with the CC chemokine-binding protein Evasin-4 improves post-infarction myocardial injury and survival in mice V Braunersreuther, F Montecucco, G Pelli, K Galan, AE Proudfoot, A Belin, ... Thrombosis and haemostasis 110 (10), 807-825, 2013 | 63 | 2013 |
| Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice A Nencioni, RF Da Silva, RA Fraga-Silva, S Steffens, M Fabre, I Bauer, ... Thrombosis and haemostasis 112 (02), 308-322, 2014 | 61 | 2014 |
