Pathogen-and host-directed anti-inflammatory activities of macrolide antibiotics HC Steel, AJ Theron, R Cockeran, R Anderson, C Feldman Mediators of inflammation 2012, 2012 | 154 | 2012 |
Overview of community-acquired pneumonia and the role of inflammatory mechanisms in the immunopathogenesis of severe pneumococcal disease HC Steel, R Cockeran, R Anderson, C Feldman Mediators of inflammation 2013, 2013 | 151 | 2013 |
Proinflammatory interactions of pneumolysin with human neutrophils R Cockeran, AJ Theron, HC Steel, NM Matlola, TJ Mitchell, C Feldman, ... The Journal of infectious diseases 183 (4), 604-611, 2001 | 149 | 2001 |
Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro R Cockeran, C Durandt, C Feldman, TJ Mitchell, R Anderson The Journal of infectious diseases 186 (4), 562-565, 2002 | 108 | 2002 |
The effects of pneumolysin and hydrogen peroxide, alone and in combination, on human ciliated epithelium in vitro C Feldman, R Anderson, R Cockeran, T Mitchell, P Cole, R Wilson Respiratory medicine 96 (8), 580-585, 2002 | 100 | 2002 |
The role of pneumolysin in the pathogenesis of Streptococcus pneumoniae infection R Cockeran, R Anderson, C Feldman Current opinion in infectious diseases 15 (3), 235-239, 2002 | 94 | 2002 |
Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in … R Anderson, HC Steel, R Cockeran, A Von Gottberg, L De Gouveia, ... Journal of Antimicrobial Chemotherapy 60 (5), 1155-1158, 2007 | 78 | 2007 |
Effects of cigarette smoke condensate on pneumococcal biofilm formation and pneumolysin ND Mutepe, R Cockeran, HC Steel, AJ Theron, TJ Mitchell, C Feldman, ... European Respiratory Journal 41 (2), 392-395, 2013 | 75 | 2013 |
Pneumolysin Potentiates Production of Prostaglandin E2 and Leukotriene B4 by Human Neutrophils R Cockeran, HC Steel, TJ Mitchell, C Feldman, R Anderson Infection and immunity 69 (5), 3494-3496, 2001 | 72 | 2001 |
Clarithromycin alone and in combination with ceftriaxone inhibits the production of pneumolysin by both macrolide-susceptible and macrolide-resistant strains of Streptococcus … R Anderson, HC Steel, R Cockeran, AM Smith, A Von Gottberg, ... Journal of Antimicrobial Chemotherapy 59 (2), 224-229, 2007 | 63 | 2007 |
Effects of clofazimine on potassium uptake by a Trk-deletion mutant of Mycobacterium tuberculosis MC Cholo, HI Boshoff, HC Steel, R Cockeran, NM Matlola, KJ Downing, ... Journal of Antimicrobial Chemotherapy 57 (1), 79-84, 2006 | 60 | 2006 |
Pneumolysin-mediated activation of NFκB in human neutrophils is antagonized by docosahexaenoic acid H Fickl, R Cockeran, HC Steel, C Feldman, G Cowan, TJ Mitchell, ... Clinical & Experimental Immunology 140 (2), 274-281, 2005 | 42 | 2005 |
Beneficial and harmful interactions of antibiotics with microbial pathogens and the host innate immune system R Anderson, G Tintinger, R Cockeran, M Potjo, C Feldman Pharmaceuticals 3 (5), 1694-1710, 2010 | 38 | 2010 |
Hyaluronidase augments pneumolysin-mediated injury to human ciliated epithelium C Feldman, R Cockeran, MJ Jedrzejas, TJ Mitchell, R Anderson International Journal of Infectious Diseases 11 (1), 11-15, 2007 | 35 | 2007 |
Interactive inhibitory effects of formoterol and montelukast on activated human neutrophils CM Gravett, AJ Theron, HC Steel, GR Tintinger, R Cockeran, C Feldman, ... European Respiratory Journal 36 (6), 1417-1424, 2010 | 30 | 2010 |
Pneumolysin as a vaccine and drug target in the prevention and treatment of invasive pneumococcal disease R Cockeran, R Anderson, C Feldman ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS-ENGLISH EDITION- 53 (3), 189, 2005 | 30 | 2005 |
Antimicrobial activity of clofazimine is not dependent on mycobacterial C-type phospholipases MC Bopape, HC Steel, R Cockeran, NM Matlola, PB Fourie, R Anderson Journal of Antimicrobial Chemotherapy 53 (6), 971-974, 2004 | 25 | 2004 |
Exposure of a 23F serotype strain of Streptococcus pneumoniae to cigarette smoke condensate is associated with selective upregulation of genes encoding the two-component … R Cockeran, JA Herbert, TJ Mitchell, T Dix-Peek, C Dickens, R Anderson, ... BioMed Research International 2014, 2014 | 24 | 2014 |
Platelet‐activating factor and lyso‐PAF possess direct antimicrobial properties in vitro HC Steel, R Cockeran, R Anderson Apmis 110 (2), 158-164, 2002 | 23 | 2002 |
Interleukin-10 and interleukin-1 receptor antagonist distinguish between patients with sepsis and the systemic inflammatory response syndrome (SIRS) M Potjo, AJ Theron, R Cockeran, NN Sipholi, HC Steel, TV Bale, ... Cytokine 120, 227-233, 2019 | 22 | 2019 |