Gareth Bond
Gareth Bond
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A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
GL Bond, W Hu, EE Bond, H Robins, SG Lutzker, NC Arva, J Bargonetti, ...
Cell 119 (5), 591-602, 2004
The genetics of the p53 pathway, apoptosis and cancer therapy
A Vazquez, EE Bond, AJ Levine, GL Bond
Nature reviews Drug discovery 7 (12), 979-987, 2008
MDM2 is a central node in the p53 pathway: 12 years and counting
GL Bond, W Hu, AJ Levine
Current cancer drug targets 5 (1), 3-8, 2005
MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner
GL Bond, KM Hirshfield, T Kirchhoff, G Alexe, EE Bond, H Robins, F Bartel, ...
Cancer research 66 (10), 5104-5110, 2006
A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect
GL Bond, W Hu, A Levine
Cancer research 65 (13), 5481-5484, 2005
A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence cancer in humans
GL Bond, AJ Levine
Oncogene 26 (9), 1317-1323, 2007
The importance of p53 pathway genetics in inherited and somatic cancer genomes
G Stracquadanio, X Wang, MD Wallace, AM Grawenda, P Zhang, J Hewitt, ...
Nature reviews Cancer 16 (4), 251-265, 2016
A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells
NC Arva, TR Gopen, KE Talbott, LE Campbell, A Chicas, DE White, ...
Journal of Biological Chemistry 280 (29), 26776-26787, 2005
Identification and functional characterization of neo-poly (A) polymerase, an RNA processing enzyme overexpressed in human tumors
SL Topalian, S Kaneko, MI Gonzales, GL Bond, Y Ward, JL Manley
Molecular and cellular biology, 2001
A polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection
J Zeron-Medina, X Wang, E Repapi, MR Campbell, D Su, F Castro-Giner, ...
Cell 155 (2), 410-422, 2013
A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development
SM Post, A Quintás-Cardama, V Pant, T Iwakuma, A Hamir, JG Jackson, ...
Cancer cell 18 (3), 220-230, 2010
MDM2 SNP309 accelerates colorectal tumour formation in women
GL Bond, C Menin, R Bertorelle, P Alhopuro, LA Aaltonen, AJ Levine
Journal of medical genetics 43 (12), 950-952, 2006
Single-nucleotide polymorphisms in the p53 signaling pathway
LF Grochola, J Zeron-Medina, S Mériaux, GL Bond
Cold Spring Harbor perspectives in biology 2 (5), a001032, 2010
Detection of functional single-nucleotide polymorphisms that affect apoptosis
SL Harris, G Gil, H Robins, W Hu, K Hirshfield, E Bond, G Bond, AJ Levine
Proceedings of the National Academy of Sciences 102 (45), 16297-16302, 2005
MEF2 transcription factors are key regulators of sprouting angiogenesis
N Sacilotto, KM Chouliaras, LL Nikitenko, YW Lu, M Fritzsche, ...
Genes & development 30 (20), 2297-2309, 2016
Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice
B Leroy, ML Ballinger, F Baran-Marszak, GL Bond, A Braithwaite, ...
Cancer research 77 (6), 1250-1260, 2017
Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene
GS Atwal, T Kirchhoff, EE Bond, M Montagna, C Menin, R Bertorelle, ...
Proceedings of the National Academy of Sciences 106 (25), 10236-10241, 2009
Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer
K Lenos, AM Grawenda, K Lodder, ML Kuijjer, AFAS Teunisse, E Repapi, ...
Cancer research 72 (16), 4074-4084, 2012
Haplotype structure and selection of the MDM2 oncogene in humans
GS Atwal, GL Bond, S Metsuyanim, M Papa, E Friedman, ...
Proceedings of the National Academy of Sciences 104 (11), 4524-4529, 2007
Venous identity requires BMP signalling through ALK3
A Neal, S Nornes, S Payne, MD Wallace, M Fritzsche, P Louphrasitthiphol, ...
Nature communications 10 (1), 453, 2019
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