Andy J Chien
Andy J Chien
University of Washington School of Medicine
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Dysregulation of Wnt/β-catenin signaling in gastrointestinal cancers
BD White, AJ Chien, DW Dawson
Gastroenterology 142 (2), 219-232, 2012
A Wnt survival guide: from flies to human disease
AJ Chien, WH Conrad, RT Moon
Journal of Investigative Dermatology 129 (7), 1614-1627, 2009
Activated Wnt/-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model
AJ Chien, EC Moore, AS Lonsdorf, RM Kulikauskas, BG Rothberg, ...
Proceedings of the National Academy of Sciences 106 (4), 1193-1198, 2009
Roles of a membrane-localized βsubunit in the formation and targeting of functional L-type Ca2+ channels
AJ Chien, X Zhao, RE Shirokov, TS Puri, CF Chang, D Sun, E Rios, ...
Journal of Biological Chemistry 270 (50), 30036-30044, 1995
Identification of palmitoylation sites within the L-type calcium channel β2a subunit and effects on channel function
AJ Chien, KM Carr, RE Shirokov, E Rios, MM Hosey
Journal of Biological Chemistry 271 (43), 26465-26468, 1996
Identification and subcellular localization of the subunits of L-type calcium channels and adenylyl cyclase in cardiac myocytes
T Gao, TS Puri, BL Gerhardstein, AJ Chien, RD Green, MM Hosey
Journal of Biological Chemistry 272 (31), 19401-19407, 1997
Identification of the Sites Phosphorylated by Cyclic AMP-Dependent Protein Kinase on the β2 Subunit of L-Type Voltage-Dependent Calcium Channels
BL Gerhardstein, TS Puri, AJ Chien, MM Hosey
Biochemistry 38 (32), 10361-10370, 1999
Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma
TL Biechele, RM Kulikauskas, RA Toroni, OM Lucero, RD Swift, ...
Science signaling 5 (206), ra3-ra3, 2012
WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors
JN Anastas, RM Kulikauskas, T Tamir, H Rizos, GV Long, EM Von Euw, ...
The Journal of clinical investigation 124 (7), 2877-2890, 2014
New regulators of Wnt/β-catenin signaling revealed by integrative molecular screening
MB Major, BS Roberts, JD Berndt, S Marine, J Anastas, N Chung, ...
Science signaling 1 (45), ra12-ra12, 2008
Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis
SL Lai, AJ Chien, RT Moon
Cell research 19 (5), 532-545, 2009
Complexes of the α1C and β subunits generate the necessary signal for membrane targeting of class C L-type calcium channels
T Gao, AJ Chien, MM Hosey
Journal of Biological Chemistry 274 (4), 2137-2144, 1999
A re-evaluation of the “oncogenic” nature of Wnt/β-catenin signaling in melanoma and other cancers
OM Lucero, DW Dawson, RT Moon, AJ Chien
Current oncology reports 12 (5), 314-318, 2010
Sorcin associates with the pore-forming subunit of voltage-dependent L-type Ca2+ channels
MB Meyers, TS Puri, AJ Chien, T Gao, PH Hsu, MM Hosey, GI Fishman
Journal of Biological Chemistry 273 (30), 18930-18935, 1998
Membrane targeting of L-type calcium channels: role of palmitoylation in the subcellular localization of the β2a subunit
AJ Chien, T Gao, E Perez-Reyes, MM Hosey
Journal of Biological Chemistry 273 (36), 23590-23597, 1998
WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma
MD Arensman, AN Kovochich, RM Kulikauskas, AR Lay, PT Yang, X Li, ...
Oncogene 33 (7), 899-908, 2014
Targeting Wnt pathways in disease
ZF Zimmerman, RT Moon, AJ Chien
Cold Spring Harbor perspectives in biology 4 (11), a008086, 2012
WNTS and WNT receptors as therapeutic tools and targets in human disease processes
AJ Chien, RT Moon
Frontiers in bioscience: a journal and virtual library 12, 448, 2007
CTLA-4 Is a Direct Target of Wnt/β-Catenin Signaling and Is Expressed in Human Melanoma Tumors
KV Shah, AJ Chien, C Yee, RT Moon
Journal of Investigative Dermatology 128 (12), 2870-2879, 2008
Activation of Wnt/β-catenin signaling increases apoptosis in melanoma cells treated with trail
ZF Zimmerman, RM Kulikauskas, K Bomsztyk, RT Moon, AJ Chien
PloS one 8 (7), e69593, 2013
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