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Jimmy Dikeakos
Jimmy Dikeakos
Professor
Verified email at uwo.ca
Title
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Cited by
Year
Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53
P Di Lello, LMM Jenkins, TN Jones, BD Nguyen, T Hara, H Yamaguchi, ...
Molecular cell 22 (6), 731-740, 2006
2392006
Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy
I Ullah, J Prévost, MS Ladinsky, H Stone, M Lu, SP Anand, ...
Immunity 54 (9), 2143-2158. e15, 2021
1652021
Sending proteins to dense core secretory granules: still a lot to sort out
JD Dikeakos, TL Reudelhuber
The Journal of cell biology 177 (2), 191-196, 2007
1542007
Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2
R Gasser, M Cloutier, J Prévost, C Fink, É Ducas, S Ding, N Dussault, ...
Cell reports 34 (9), 2021
1002021
Small Molecule Inhibition of HIV-1–Induced MHC-I Down-Regulation Identifies a Temporally Regulated Switch in Nef Action
JD Dikeakos, KM Atkins, L Thomas, L Emert-Sedlak, IJL Byeon, J Jung, ...
Molecular biology of the cell 21 (19), 3279-3292, 2010
862010
An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I
JD Dikeakos, L Thomas, G Kwon, J Elferich, U Shinde, G Thomas
Molecular biology of the cell 23 (11), 2184-2197, 2012
822012
HIV-1 Nef: a master manipulator of the membrane trafficking machinery mediating immune evasion
EN Pawlak, JD Dikeakos
Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (4), 733-741, 2015
792015
HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling
BS Dirk, EN Pawlak, AL Johnson, LR Van Nynatten, RA Jacob, B Heit, ...
Scientific reports 6 (1), 37021, 2016
752016
The multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest
KM Atkins, LL Thomas, J Barroso-Gonzalez, L Thomas, S Auclair, J Yin, ...
Cell reports 8 (5), 1545-1557, 2014
692014
KIM-1/TIM-1 is a Receptor for SARS-CoV-2 in Lung and Kidney
Y Mori, C Fink, T Ichimura, K Sako, M Mori, NN Lee, P Aschauer, ...
MedRxiv, 2020.09. 16.20190694, 2020
682020
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster …
NW Werneburg, SF Bronk, ME Guicciardi, L Thomas, JD Dikeakos, ...
Journal of Biological Chemistry 287 (29), 24427-24437, 2012
642012
Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease
JD Dikeakos, P Di Lello, MJ Lacombe, R Ghirlando, P Legault, ...
Proceedings of the National Academy of Sciences 106 (18), 7408-7413, 2009
502009
MIiSR: molecular interactions in super-resolution imaging enables the analysis of protein interactions, dynamics and formation of multi-protein structures
FA Caetano, BS Dirk, JHK Tam, PC Cavanagh, M Goiko, SSG Ferguson, ...
PLoS computational biology 11 (12), e1004634, 2015
432015
PC1/3, PC2 and PC5/6A are targeted to dense core secretory granules by a common mechanism
JD Dikeakos, C Mercure, MJ Lacombe, NG Seidah, TL Reudelhuber
The FEBS journal 274 (16), 4094-4102, 2007
392007
A hydrophobic patch in a charged α-helix is sufficient to target proteins to dense core secretory granules
JD Dikeakos, MJ Lacombe, C Mercure, M Mireuta, TL Reudelhuber
Journal of biological chemistry 282 (2), 1136-1143, 2007
362007
The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4+ T cells
EN Pawlak, BS Dirk, RA Jacob, AL Johnson, JD Dikeakos
Retrovirology 15, 1-22, 2018
322018
Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export
MW Woods, JG Tong, SK Tom, PA Szabo, PC Cavanagh, JD Dikeakos, ...
Retrovirology 11, 1-17, 2014
322014
HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4+ T Cells
J Prévost, CR Edgar, J Richard, SM Trothen, RA Jacob, MJ Mumby, ...
Journal of Virology 94 (7), 10.1128/jvi. 01999-19, 2020
312020
Soluble CD93 is an apoptotic cell opsonin recognized by αxβ2
JWD Blackburn, DHC Lau, EY Liu, J Ellins, AM Vrieze, EN Pawlak, ...
European Journal of Immunology 49 (4), 600-610, 2019
302019
Efferocytic defects in early atherosclerosis are driven by GATA2 overexpression in macrophages
C Yin, AM Vrieze, M Rosoga, J Akingbasote, EN Pawlak, RA Jacob, J Hu, ...
Frontiers in immunology 11, 594136, 2020
282020
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