High frequency of germline RUNX1 mutations in patients with RUNX1-mutated AML L Simon, JF Spinella, CY Yao, VP Lavallée, I Boivin, G Boucher, ... Blood, The Journal of the American Society of Hematology 135 (21), 1882-1886, 2020 | 76 | 2020 |
UM171 preserves epigenetic marks that are reduced in ex vivo culture of human HSCs via potentiation of the CLR3-KBTBD4 complex J Chagraoui, S Girard, JF Spinella, L Simon, E Bonneil, N Mayotte, ... Cell Stem Cell 28 (1), 48-62. e6, 2021 | 57 | 2021 |
UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal J Chagraoui, B Lehnertz, S Girard, JF Spinella, I Fares, E Tomellini, ... PLoS One 14 (11), e0224900, 2019 | 51 | 2019 |
Chemogenomic Landscape of RUNX1-mutated AML Reveals Importance of RUNX1 Allele Dosage in Genetics and Glucocorticoid Sensitivity L Simon, VP Lavallée, ME Bordeleau, J Krosl, I Baccelli, G Boucher, ... Clinical cancer research 23 (22), 6969-6981, 2017 | 48 | 2017 |
Fabry disease: a new approach for the screening of females in high-risk groups G Pasqualim, L Simon, F Sperb-Ludwig, MG Burin, K Michelin-Tirelli, ... Clinical biochemistry 47 (7-8), 657-662, 2014 | 26 | 2014 |
Bone marrow mesenchymal stromal cell uptake extracellular vesicles from carbon tetrachloride-injured hepatocytes without differentiating into hepatocyte-like cells in a short … VA Angiolini, C Uribe-Cruz, G Rodrigues, L Simon, ML López, U Matte Cytotherapy 20 (6), 895-898, 2018 | 22 | 2018 |
Prevalence and phenotypic expression of mutations in the MYH7, MYBPC3 and TNNT2 genes in families with hypertrophic cardiomyopathy in the south of Brazil: a cross-sectional study FL Scolari, MAR Torres, L Simon, VC Freitas, R Giugliani, Ú Matte Arquivos brasileiros de cardiologia 107, 257-265, 2016 | 18 | 2016 |
Diagnostic contribution of molecular analysis of the cystic fibrosis transmembrane conductance regulator gene in patients suspected of having mild or atypical cystic fibrosis VB Dal'Maso, L Mallmann, M Siebert, L Simon, ML Saraiva-Pereira, ... Jornal Brasileiro de Pneumologia 39, 181-189, 2013 | 12 | 2013 |
Encapsulated platelets modulate kupffer cell activation and reduce oxidative stress in a model of acute liver failure ML López, C Uribe‐Cruz, A Osvaldt, CO Kieling, L Simon, S Tobar, ... Liver Transplantation 22 (11), 1562-1572, 2016 | 9 | 2016 |
Injured hepatocyte-released microvesicles induce bone marrow-derived mononuclear cells differentiation L Simon, M López, C Uribe-Cruz, DFP Vergara, L Silla, U Matte Differentiation 90 (1-3), 40-47, 2015 | 8 | 2015 |
Bone marrow-derived mononuclear cells differentiate into hepatocyte-like cells within few Hrs without fusion U Matte, CU Cruz, ML López, L Simon, FQ Mayer, R Giugliani Journal of Cell Science & Therapy 5 (3), 1, 2014 | 6 | 2014 |
Alginate-embedded HuH-7 cells increase MMP-9 and reduce OCLN expression in vitro VA Angiolini, CU Cruz, ML López, L Simon, U Matte Cancer Cell International 17, 1-6, 2017 | 3 | 2017 |
Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1-Mutated AML to Glucocorticoids L Simon, VP Lavallee, ME Bordeleau, B Lehnertz, T MacRae, ... Blood 132, 4675, 2018 | 1 | 2018 |
Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia A Hajmirza, L Simon, J Chagraoui, N Mayotte, JF Spinella, T Macrae, ... Blood 140 (Supplement 1), 8825-8826, 2022 | | 2022 |
3082–EXPLORING GLUCOCORTICOID SENSITIVITY MODULATORS IN HUMAN ACUTE MYELOID LEUKEMIA A Hajmirza, L Simon, JF Spinella, T MacRae, B Lehnertz, J Chagraoui, ... Experimental Hematology 88, S63, 2020 | | 2020 |
RUNX1 dosage dictates gene signature and in vitro response to glucocorticoids in acute myeloid leukemia L Simon, VP Lavallée, ME Bordeleau, J Krosl, I Baccelli, G Boucher, ... Cancer Research 77 (13_Supplement), 1509-1509, 2017 | | 2017 |
Targeted therapy in aml: looking beyond mutations with leucegene project G Sauvageau, A Marinier, S Lemieux, C Thiollier, L Simon, R Bisaillon, ... Experimental Hematology 44 (9), S29, 2016 | | 2016 |