| Squalene hopene cyclases: highly promiscuous and evolvable catalysts for stereoselective CC and CX bond formation SC Hammer, PO Syrén, M Seitz, BM Nestl, B Hauer Current opinion in chemical biology 17 (2), 293-300, 2013 | 74 | 2013 |
| Synthesis of heterocyclic terpenoids by promiscuous squalene-hopene cyclases. M Seitz, PO Syrén, L Steiner, J Klebensberger, BM Nestl, B Hauer Chembiochem: a European Journal of Chemical Biology 14 (4), 436-439, 2013 | 63 | 2013 |
| Biocatalysis in the recycling landscape for synthetic polymers and plastics towards circular textiles C Jönsson, R Wei, A Biundo, J Landberg, L Schwarz Bour, F Pezzotti, ... ChemSusChem 14 (19), 4028-4040, 2021 | 58 | 2021 |
| Amidases have a hydrogen bond that facilitates nitrogen inversion, but esterases have not PO Syrén, K Hult ChemCatChem 3 (5), 853-860, 2011 | 56 | 2011 |
| Squalene-hopene cyclases—evolution, dynamics and catalytic scope PO Syren, S Henche, A Eichler, BM Nestl, B Hauer Current opinion in structural biology 41, 73-82, 2016 | 53 | 2016 |
| Mutated variant of Candida antarctica lipase B in (S)-selective dynamic kinetic resolution of secondary alcohols K Engström, M Vallin, PO Syrén, K Hult, JE Bäckvall Organic & Biomolecular Chemistry 9 (1), 81-82, 2011 | 50 | 2011 |
| Mutations in the stereospecificity pocket and at the entrance of the active site of Candida antarctica lipase B enhancing enzyme enantioselectivity Z Marton, V Léonard-Nevers, PO Syrén, C Bauer, S Lamare, K Hult, ... Journal of Molecular Catalysis B: Enzymatic 65 (1-4), 11-17, 2010 | 49 | 2010 |
| Conformational selection in biocatalytic plastic degradation by PETase B Guo, SR Vanga, X Lopez-Lorenzo, P Saenz-Mendez, SR Ericsson, ... Acs Catalysis 12 (6), 3397-3409, 2022 | 44 | 2022 |
| Entropy is key to the formation of pentacyclic terpenoids by enzyme‐catalyzed polycyclization PO Syrén, SC Hammer, B Claasen, B Hauer Angewandte Chemie 126 (19), 4945-4949, 2014 | 43 | 2014 |
| Chemo-enzymatic pathways toward pinene-based renewable materials A Stamm, M Tengdelius, B Schmidt, J Engström, PO Syrén, L Fogelström, ... Green chemistry 21 (10), 2720-2731, 2019 | 42 | 2019 |
| Stereoselective Friedel–Crafts alkylation catalyzed by squalene hopene cyclases SC Hammer, JM Dominicus, PO Syrén, BM Nestl, B Hauer Tetrahedron 68 (37), 7624-7629, 2012 | 39 | 2012 |
| Ancestral diterpene cyclases show increased thermostability and substrate acceptance NM Hendrikse, G Charpentier, E Nordling, PO Syrén The FEBS journal 285 (24), 4660-4673, 2018 | 38 | 2018 |
| Esterases with an introduced amidase-like hydrogen bond in the transition state have increased amidase specificity PO Syrén, P Hendil-Forssell, L Aumailley, W Besenmatter, F Gounine, ... ChemBioChem (Print) 13 (5), 645-648, 2012 | 36 | 2012 |
| Increased activity of enzymatic transacylation of acrylates through rational design of lipases PO Syrén, E Lindgren, HW Hoeffken, C Branneby, S Maurer, B Hauer, ... Journal of Molecular Catalysis B: Enzymatic 65 (1-4), 3-10, 2010 | 36 | 2010 |
| Mutant Lipase‐Catalyzed Kinetic Resolution of Bulky Phenyl Alkyl sec‐Alcohols: A Thermodynamic Analysis of Enantioselectivity M Vallin, PO Syrén, K Hult ChemBioChem 11 (3), 411-416, 2010 | 36 | 2010 |
| Engineering of ancestors as a tool to elucidate structure, mechanism, and specificity of extant terpene cyclase K Schriever, P Saenz-Mendez, RS Rudraraju, NM Hendrikse, EP Hudson, ... Journal of the American Chemical Society 143 (10), 3794-3807, 2021 | 33 | 2021 |
| The solution of nitrogen inversion in amidases PO Syrén The FEBS journal 280 (13), 3069-3083, 2013 | 31 | 2013 |
| Exploring the therapeutic potential of modern and ancestral phenylalanine/tyrosine ammonia-lyases as supplementary treatment of hereditary tyrosinemia NM Hendrikse, A Holmberg Larsson, S Svensson Gelius, S Kuprin, ... Scientific Reports 10 (1), 1315, 2020 | 30 | 2020 |
| Proton Shuttle Mechanism in the Transition State of Lipase‐Catalyzed N‐Acylation of Amino Alcohols PO Syrén, F Le Joubioux, Y Ben Henda, T Maugard, K Hult, M Graber ChemCatChem 5 (7), 1842-1853, 2013 | 24 | 2013 |
| A Retro‐biosynthesis‐Based Route to Generate Pinene‐Derived Polyesters A Stamm, A Biundo, B Schmidt, J Brücher, S Lundmark, P Olsén, ... ChemBioChem 20 (13), 1664-1671, 2019 | 23 | 2019 |
Bettina NestlGroup Leader, University of StuttgartVerified email at itb.uni-stuttgart.de
