Alex Strongin
Alex Strongin
Professor, SBMRI
Verified email at - Homepage
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Mechanism of cell surface activation of 72-kDa type IV collagenase: isolation of the activated form of the membrane metalloprotease
AY Strongin, I Collier, G Bannikov, BL Marmer, GA Grant, GI Goldberg
Journal of Biological Chemistry 270 (10), 5331-5338, 1995
Compensation mechanism in tumor cell migration: mesenchymal–amoeboid transition after blocking of pericellular proteolysis
K Wolf, I Mazo, H Leung, K Engelke, UH Von Andrian, EI Deryugina, ...
The Journal of cell biology 160 (2), 267-277, 2003
S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death
Z Gu, M Kaul, B Yan, SJ Kridel, J Cui, A Strongin, JW Smith, ...
Science 297 (5584), 1186-1190, 2002
Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation …
GI Goldberg, A Strongin, IE Collier, LT Genrich, BL Marmer
Journal of Biological Chemistry 267 (7), 4583-4591, 1992
A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia
Z Gu, J Cui, S Brown, R Fridman, S Mobashery, AY Strongin, SA Lipton
Journal of Neuroscience 25 (27), 6401-6408, 2005
MT1-MMP initiates activation of pro-MMP-2 and integrin αvβ3 promotes maturation of MMP-2 in breast carcinoma cells
EI Deryugina, B Ratnikov, E Monosov, TI Postnova, R DiScipio, JW Smith, ...
Experimental cell research 263 (2), 209-223, 2001
Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2
AY Strongin, BL Marmer, GA Grant, GI Goldberg
Journal of Biological Chemistry 268 (19), 14033-14039, 1993
Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion
AM Belkin, SS Akimov, LS Zaritskaya, BI Ratnikov, EI Deryugina, ...
Journal of Biological Chemistry 276 (21), 18415-18422, 2001
Processing of integrin αv subunit by membrane type 1 matrix metalloproteinase stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine …
EI Deryugina, BI Ratnikov, TI Postnova, DV Rozanov, AY Strongin
Journal of Biological Chemistry 277 (12), 9749-9756, 2002
Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2
EI Deryugina, MA Bourdon, RA Reisfeld, A Strongin
Cancer research 58 (16), 3743-3750, 1998
Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein
D Luo, T Xu, RP Watson, D Scherer‐Becker, A Sampath, W Jahnke, ...
The EMBO journal 27 (23), 3209-3219, 2008
Up-regulation of vascular endothelial growth factor by membrane-type 1 matrix metalloproteinase stimulates human glioma xenograft growth and angiogenesis
EI Deryugina, L Soroceanu, AY Strongin
Cancer research 62 (2), 580-588, 2002
Functional activation of integrin αvβ3 in tumor cells expressing membrane‐type 1 matrix metalloproteinase
EI Deryugina, MA Bourdon, K Jungwirth, JW Smith, AY Strongin
International journal of cancer 86 (1), 15-23, 2000
Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold
AE Aleshin, SA Shiryaev, AY Strongin, RC Liddington
Protein science 16 (5), 795-806, 2007
Characterization of matrix metalloproteinase-26, a novel metalloproteinase widely expressed in cancer cells of epithelial origin
Biochemical Journal 356 (3), 705-718, 2001
Matrix metalloproteinase-2 activation modulates glioma cell migration
EI Deryugina, MA Bourdon, GX Luo, RA Reisfeld, A Strongin
Journal of Cell Science 110 (19), 2473-2482, 1997
MMP-28, a new human matrix metalloproteinase with an unusual cysteine-switch sequence is widely expressed in tumors
GN Marchenko, AY Strongin
Gene 265 (1-2), 87-93, 2001
Mutation Analysis of Membrane Type-1 Matrix Metalloproteinase (MT1-MMP): THE ROLE OF THE CYTOPLASMIC TAIL CYS574, THE ACTIVE SITE GLU240, AND FURIN CLEAVAGE MOTIFS IN …
DV Rozanov, EI Deryugina, BI Ratnikov, EZ Monosov, GN Marchenko, ...
Journal of Biological Chemistry 276 (28), 25705-25714, 2001
Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2.
EI Deryugina, GX Luo, RA Reisfeld, MA Bourdon, A Strongin
Anticancer research 17 (5A), 3201-3210, 1997
Alanine scanning mutagenesis and functional analysis of the fibronectin-like collagen-binding domain from human 92-kDa type IV collagenase.
IE Collier, PA Krasnov, AY Strongin, H Birkedal-Hansen, GI Goldberg
Journal of Biological Chemistry 267 (10), 6776-6781, 1992
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