Update of P2X receptor properties and their pharmacology: IUPHAR Review 30 P Illes, CE Müller, KA Jacobson, T Grutter, A Nicke, SJ Fountain, ... British Journal of Pharmacology 178 (3), 489-514, 2021 | 212 | 2021 |
An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum SJ Fountain, K Parkinson, MT Young, L Cao, CRL Thompson, RA North Nature 448 (7150), 200-203, 2007 | 174 | 2007 |
Human TRPC5 channel activated by a multiplicity of signals in a single cell F Zeng, SZ Xu, PK Jackson, D McHugh, B Kumar, SJ Fountain, DJ Beech The Journal of physiology 559 (3), 739-750, 2004 | 155 | 2004 |
P2X4 receptor function in the nervous system and current breakthroughs in pharmacology L Stokes, JA Layhadi, L Bibic, K Dhuna, SJ Fountain Frontiers in pharmacology 8, 291, 2017 | 133 | 2017 |
An evolutionary history of P2X receptors SJ Fountain, G Burnstock Purinergic signalling 5, 269-272, 2009 | 103 | 2009 |
Permeation properties of a P2X receptor in the green algae Ostreococcus tauri SJ Fountain, L Cao, MT Young, RA North Journal of Biological Chemistry 283 (22), 15122-15126, 2008 | 98 | 2008 |
ATP evokes Ca2+ responses and CXCL5 secretion via P2X4 receptor activation in human monocyte-derived macrophages JA Layhadi, J Turner, D Crossman, SJ Fountain The Journal of Immunology 200 (3), 1159-1168, 2018 | 83 | 2018 |
A C-terminal lysine that controls human P2X4 receptor desensitization SJ Fountain, RA North Journal of Biological Chemistry 281 (22), 15044-15049, 2006 | 81 | 2006 |
Action of MK‐7264 (gefapixant) at human P2X3 and P2X2/3 receptors and in vivo efficacy in models of sensitisation D Richards, JR Gever, AP Ford, SJ Fountain British journal of pharmacology 176 (13), 2279-2291, 2019 | 70 | 2019 |
Thr339-to-serine substitution in rat P2X2 receptor second transmembrane domain causes constitutive opening and indicates a gating role for Lys308 L Cao, MT Young, HE Broomhead, SJ Fountain, RA North Journal of Neuroscience 27 (47), 12916-12923, 2007 | 68 | 2007 |
Constitutive lysosome exocytosis releases ATP and engages P2Y receptors in human monocytes V Sivaramakrishnan, S Bidula, H Campwala, D Katikaneni, SJ Fountain Journal of cell science 125 (19), 4567-4575, 2012 | 67 | 2012 |
Molecular shape, architecture, and size of P2X4 receptors determined using fluorescence resonance energy transfer and electron microscopy MT Young, JA Fisher, SJ Fountain, RC Ford, RA North, BS Khakh Journal of biological chemistry 283 (38), 26241-26251, 2008 | 61 | 2008 |
P2X4 Receptor-Dependent Ca2+ Influx in Model Human Monocytes and Macrophages JA Layhadi, SJ Fountain International journal of molecular sciences 18 (11), 2261, 2017 | 52 | 2017 |
Primitive ATP-activated P2X receptors: discovery, function and pharmacology SJ Fountain Frontiers in cellular neuroscience 7, 247, 2013 | 49 | 2013 |
Functional up‐regulation of KCNA gene family expression in murine mesenteric resistance artery smooth muscle SJ Fountain, A Cheong, R Flemming, L Mair, A Sivaprasadarao, ... The Journal of Physiology 556 (1), 29-42, 2004 | 47 | 2004 |
Kv1.5 potassium channel gene regulation by Sp1 transcription factor and oxidative stress SJ Fountain, A Cheong, J Li, NY Dondas, F Zeng, IC Wood, DJ Beech American Journal of Physiology-Heart and Circulatory Physiology 293 (5 …, 2007 | 40 | 2007 |
P2Y12 receptor modulation of ADP‐evoked intracellular Ca2+ signalling in THP‐1 human monocytic cells JJ Micklewright, JA Layhadi, SJ Fountain British Journal of Pharmacology 175 (12), 2483-2491, 2018 | 37 | 2018 |
P2Y6 receptor inhibition perturbs CCL2-evoked signalling in human monocytic and peripheral blood mononuclear cells H Campwala, DW Sexton, DC Crossman, SJ Fountain Journal of cell science 127 (22), 4964-4973, 2014 | 37 | 2014 |
Fluvastatin suppresses native and recombinant human P2X4 receptor function J Li, SJ Fountain Purinergic signalling 8, 311-316, 2012 | 32 | 2012 |
ATP-Evoked Intracellular Ca2+ Responses in M-CSF Differentiated Human Monocyte-Derived Macrophage are Mediated by P2X4 and P2Y11 Receptor Activation JA Layhadi, SJ Fountain International journal of molecular sciences 20 (20), 5113, 2019 | 25 | 2019 |