Metabologenomics: correlation of microbial gene clusters with metabolites drives discovery of a nonribosomal peptide with an unusual amino acid monomer AW Goering, RA McClure, JR Doroghazi, JC Albright, NA Haverland, ... ACS central science 2 (2), 99-108, 2016 | 126 | 2016 |
In Vitro Reconstruction of Nonribosomal Peptide Biosynthesis Directly from DNA Using Cell-Free Protein Synthesis AW Goering, J Li, RA McClure, RJ Thomson, MC Jewett, NL Kelleher ACS synthetic biology 6 (1), 39-44, 2017 | 96 | 2017 |
Large-Scale Metabolomics Reveals a Complex Response of Aspergillus nidulans to Epigenetic Perturbation JC Albright, MT Henke, AA Soukup, RA McClure, RJ Thomson, NP Keller, ... ACS chemical biology 10 (6), 1535-1541, 2015 | 93 | 2015 |
Natural products from thioester reductase containing biosynthetic pathways MW Mullowney, RA McClure, MT Robey, NL Kelleher, RJ Thomson Natural product reports 35 (9), 847-878, 2018 | 67 | 2018 |
New Aspercryptins, Lipopeptide Natural Products, Revealed by HDAC Inhibition in Aspergillus nidulans MT Henke, AA Soukup, AW Goering, RA McClure, RJ Thomson, NP Keller, ... ACS chemical biology 11 (8), 2117-2123, 2016 | 55 | 2016 |
Elucidating the rimosamide-detoxin natural product families and their biosynthesis using metabolite/gene cluster correlations RA McClure, AW Goering, KS Ju, JA Baccile, FC Schroeder, WW Metcalf, ... ACS chemical biology 11 (12), 3452-3460, 2016 | 49 | 2016 |
Discovery of the Tyrobetaine Natural Products and Their Biosynthetic Gene Cluster via Metabologenomics EI Parkinson, JH Tryon, AW Goering, KS Ju, RA McClure, JD Kemball, ... ACS chemical biology 13 (4), 1029-1037, 2018 | 43 | 2018 |
Gobichelin A and B: mixed-ligand siderophores discovered using proteomics Y Chen, M Unger, I Ntai, RA McClure, JC Albright, RJ Thomson, ... Medchemcomm 4 (1), 233-238, 2013 | 42 | 2013 |
Proteomics guided discovery of flavopeptins: Anti-proliferative aldehydes synthesized by a reductase domain-containing non-ribosomal peptide synthetase Y Chen, RA McClure, Y Zheng, RJ Thomson, NL Kelleher Journal of the American Chemical Society 135 (28), 10449-10456, 2013 | 40 | 2013 |
Impact of mass spectrometry-based technologies and strategies on chemoproteomics as a tool for drug discovery RA McClure, JD Williams ACS medicinal chemistry letters 9 (8), 785-791, 2018 | 21 | 2018 |
The HPK1 inhibitor A-745 verifies the potential of modulating T cell kinase signaling for immunotherapy S Malchow, A Korepanova, SC Panchal, RA McClure, KL Longenecker, ... ACS Chemical Biology 17 (3), 556-566, 2022 | 20 | 2022 |
Screening for expressed nonribosomal peptide synthetases and polyketide synthases using LC-MS/MS-based proteomics Y Chen, RA McClure, NL Kelleher Nonribosomal Peptide and Polyketide Biosynthesis: Methods and Protocols, 135-147, 2016 | 6 | 2016 |
Metabologenomics: Correlation of Microbial Gene Clusters with Metabolites Drives Discovery of a Nonribosomal Peptide with an Unusual Amino Acid Monomer. ACS Cent Sci. 2016; 2 … AW Goering, RA McClure, JR Doroghazi, JC Albright, NA Haverland, ... | 5 | |
Targeting IRAK3 for degradation to enhance IL-12 pro-inflammatory cytokine production A Rowley, BS Brown, M Stofega, H Hoh, R Mathew, V Marin, RX Ding, ... ACS Chemical Biology 17 (6), 1315-1320, 2022 | 4 | 2022 |
Inhibition of MALT1 and BCL2 induces synergistic anti-tumor activity in models of B cell lymphoma JP Plotnik, AE Richardson, H Yang, E Rojas, V Bontcheva, C Dowell, ... Molecular Cancer Therapeutics, 2024 | | 2024 |
MALT1 protease inhibition overcomes BTK inhibitor resistance and shows synergistic activity with venetoclax in models of B cell lymphoma and leukemia J Plotnik, V Bontcheva, C Dowell, C Will, J Chen, A Richardson, ... Blood 142, 5009, 2023 | | 2023 |
Front Cover: A Dual‐Purpose Bromocoumarin Tag Enables Deep Profiling of the Cellular Cysteinome AJ Rabalski, JD Williams, RA McClure, A Vasudevan, A Baranczak PROTEOMICS 19 (11), 1970091, 2019 | | 2019 |
A Dual‐Purpose Bromocoumarin Tag Enables Deep Profiling of the Cellular Cysteinome AJ Rabalski, JD Williams, RA McClure, A Vasudevan, A Baranczak Proteomics 19 (11), 1800433, 2019 | | 2019 |
Exploring Microbial Secondary Metabolism through Omics Technologies and Chemical Synthesis RA McClure Northwestern University, 2016 | | 2016 |
Omics-based discovery of the rimosamides: A new class of nonribosomal peptide-polyketide hybrids R McClure, J Doroghazi, A Goering, Y Chen, W Metcalf, R Thomson, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015 | | 2015 |