David S. Perlin
David S. Perlin
Hackensack Meridian Health Center for Discovery and Innovation
Verified email at hmh-cdi.org - Homepage
Cited by
Cited by
Frequency and evolution of azole resistance in Aspergillus fumigatus associated with treatment failure
SJ Howard, D Cerar, MJ Anderson, A Albarrag, MC Fisher, ...
Emerging infectious diseases 15 (7), 1068, 2009
Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of FKS Mutations and Elevated Minimum Inhibitory …
BD Alexander, MD Johnson, CD Pfeiffer, C Jiménez-Ortigosa, J Catania, ...
Clinical infectious diseases 56 (12), 1724-1732, 2013
Resistance to echinocandin-class antifungal drugs
DS Perlin
Drug Resistance Updates 10 (3), 121-130, 2007
Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates
S Park, R Kelly, JN Kahn, J Robles, MJ Hsu, E Register, W Li, V Vyas, ...
Antimicrobial Agents and Chemotherapy 49 (8), 3264-3273, 2005
Clinical breakpoints for the echinocandins and Candida revisited: integration of molecular, clinical, and microbiological data to arrive at species-specific interpretive criteria
MA Pfaller, DJ Diekema, D Andes, MC Arendrup, SD Brown, SR Lockhart, ...
Drug Resistance Updates 14 (3), 164-176, 2011
The global problem of antifungal resistance: prevalence, mechanisms, and management
DS Perlin, R Rautemaa-Richardson, A Alastruey-Izquierdo
The Lancet Infectious Diseases 17 (12), e383-e392, 2017
High-frequency triazole resistance found in nonculturable Aspergillus fumigatus from lungs of patients with chronic fungal disease
DW Denning, S Park, C Lass-Florl, MG Fraczek, M Kirwan, R Gore, ...
Clinical infectious diseases 52 (9), 1123-1129, 2011
A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin …
G Garcia-Effron, SK Katiyar, S Park, TD Edlind, DS Perlin
Antimicrobial agents and chemotherapy 52 (7), 2305-2312, 2008
Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1, 3-β-d-glucan synthase: implication for the existing susceptibility breakpoint
G Garcia-Effron, S Lee, S Park, JD Cleary, DS Perlin
Antimicrobial agents and chemotherapy 53 (9), 3690-3699, 2009
Multiple resistance mechanisms among Aspergillus fumigatus mutants with high-level resistance to itraconazole
AM Nascimento, GH Goldman, S Park, SAE Marras, G Delmas, U Oza, ...
Antimicrobial agents and chemotherapy 47 (5), 1719-1726, 2003
Correlating echinocandin MIC and kinetic inhibition of fks1 mutant glucan synthases for Candida albicans: implications for interpretive breakpoints
G Garcia-Effron, S Park, DS Perlin
Antimicrobial agents and chemotherapy 53 (1), 112-122, 2009
Mechanisms of antifungal drug resistance
LE Cowen, D Sanglard, SJ Howard, PD Rogers, DS Perlin
Cold Spring Harbor perspectives in medicine 5 (7), a019752, 2015
Echinocandin resistance: an emerging clinical problem?
MC Arendrup, DS Perlin
Current opinion in infectious diseases 27 (6), 484, 2014
Assessing resistance to the echinocandin antifungal drug caspofungin in Candida albicans by profiling mutations in FKS1
SV Balashov, S Park, DS Perlin
Antimicrobial agents and chemotherapy 50 (6), 2058-2063, 2006
Progressive loss of echinocandin activity following prolonged use for treatment of Candida albicans oesophagitis
M Laverdiere, RG Lalonde, JG Baril, DC Sheppard, S Park, DS Perlin
Journal of Antimicrobial Chemotherapy 57 (4), 705-708, 2006
Current perspectives on echinocandin class drugs
DS Perlin
Future microbiology 6 (4), 441-457, 2011
Breakthrough invasive candidiasis in patients on micafungin
CD Pfeiffer, G Garcia-Effron, AK Zaas, JR Perfect, DS Perlin, ...
Journal of clinical microbiology 48 (7), 2373-2380, 2010
Multi-azole resistance in Aspergillus fumigatus
SJ Howard, I Webster, CB Moore, RE Gardiner, S Park, DS Perlin, ...
International journal of antimicrobial agents 28 (5), 450-453, 2006
Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae.
JH McCusker, DS Perlin, JE Haber
Molecular and Cellular Biology 7 (11), 4082-4088, 1987
Requirement for ergosterol in V-ATPase function underlies antifungal activity of azole drugs
YQ Zhang, S Gamarra, G Garcia-Effron, S Park, DS Perlin, R Rao
PLoS Pathog 6 (6), e1000939, 2010
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