| Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus CJ Ott, NP Blackledge, JL Kerschner, SH Leir, GE Crawford, CU Cotton, ... Proceedings of the National Academy of Sciences 106 (47), 19934-19939, 2009 | 129 | 2009 |
| Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response EK Shanle, FH Andrews, H Meriesh, SL McDaniel, R Dronamraju, ... Genes & development 29 (17), 1795-1800, 2015 | 76 | 2015 |
| Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus R Yang, JL Kerschner, N Gosalia, D Neems, LK Gorsic, A Safi, ... Nucleic acids research 44 (7), 3082-3094, 2016 | 65 | 2016 |
| Highly efficient gene editing of cystic fibrosis patient-derived airway basal cells results in functional CFTR correction S Suzuki, AM Crane, V Anirudhan, C Barillà, N Matthias, SH Randell, ... Molecular Therapy 28 (7), 1684-1695, 2020 | 55 | 2020 |
| Architectural proteins CTCF and cohesin have distinct roles in modulating the higher order structure and expression of the CFTR locus N Gosalia, D Neems, JL Kerschner, ST Kosak, A Harris Nucleic acids research 42 (15), 9612-9622, 2014 | 53 | 2014 |
| Chromatin remodeling mediated by the FOXA1/A2 transcription factors activates CFTR expression in intestinal epithelial cells JL Kerschner, N Gosalia, SH Leir, A Harris Epigenetics 9 (4), 557-565, 2014 | 53 | 2014 |
| Transcriptional networks driving enhancer function in the CFTR gene JL Kerschner, A Harris Biochemical Journal 446 (2), 203-212, 2012 | 48 | 2012 |
| An atlas of human proximal epididymis reveals cell-specific functions and distinct roles for CFTR SH Leir, S Yin, JL Kerschner, W Cosme, A Harris Life science alliance 3 (11), 2020 | 44 | 2020 |
| FOXA2 regulates a network of genes involved in critical functions of human intestinal epithelial cells N Gosalia, R Yang, JL Kerschner, A Harris Physiological genomics 47 (7), 290-297, 2015 | 38 | 2015 |
| Functional genomics analysis of human colon organoids identifies key transcription factors S Yin, G Ray, JL Kerschner, S Hao, A Perez, ML Drumm, JA Browne, ... Physiological Genomics 52 (6), 234-244, 2020 | 25 | 2020 |
| Looping of upstream cis-regulatory elements is required for CFTR expression in human airway epithelial cells M NandyMazumdar, S Yin, A Paranjapye, JL Kerschner, H Swahn, A Ge, ... Nucleic Acids Research 48 (7), 3513-3524, 2020 | 24 | 2020 |
| Casein Kinase II Phosphorylation of Spt6 Enforces Transcriptional Fidelity by Maintaining Spn1-Spt6 Interaction R Dronamraju, JL Kerschner, SA Peck, AJ Hepperla, AT Adams, ... Cell Reports 25 (12), 3476-3489. e5, 2018 | 24 | 2018 |
| Regulatory dynamics of 11p13 suggest a role for EHF in modifying CF lung disease severity LR Stolzenburg, R Yang, JL Kerschner, S Fossum, M Xu, A Hoffmann, ... Nucleic acids research 45 (15), 8773-8784, 2017 | 23 | 2017 |
| Quantitative analysis of dynamic protein interactions during transcription reveals a role for casein kinase II in Polymerase-associated Factor (PAF) complex phosphorylation and … LG Bedard, R Dronamraju, JL Kerschner, GO Hunter, EDV Axley, ... Journal of Biological Chemistry 291 (26), 13410-13420, 2016 | 21 | 2016 |
| Nucleosome mapping across the CFTR locus identifies novel regulatory factors E Yigit, JM Bischof, Z Zhang, CJ Ott, JL Kerschner, SH Leir, ... Nucleic acids research 41 (5), 2857-2868, 2013 | 20 | 2013 |
| Hepatocyte nuclear factor 1 coordinates multiple processes in a model of intestinal epithelial cell function R Yang, JL Kerschner, A Harris Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1859 (4), 591-598, 2016 | 19 | 2016 |
| Cell function and identity revealed by comparative scRNA-seq analysis in human nasal, bronchial and epididymis epithelia A Paranjapye, SH Leir, F Huang, JL Kerschner, A Harris European journal of cell biology 101 (3), 151231, 2022 | 18 | 2022 |
| Coordinate regulation of ELF5 and EHF at the chr11p13 CF modifier region H Swahn, J Sabith Ebron, KM Lamar, S Yin, JL Kerschner, ... Journal of cellular and molecular medicine 23 (11), 7726-7740, 2019 | 17 | 2019 |
| A functional genomics approach to investigate the differentiation of iPSCs into lung epithelium at air‐liquid interface JL Kerschner, A Paranjapye, S Yin, DL Skander, G Bebek, SH Leir, ... Journal of Cellular and Molecular Medicine 24 (17), 9853-9870, 2020 | 15 | 2020 |
| An organoid model to assay the role of CFTR in the human epididymis epithelium SH Leir, S Yin, JL Kerschner, S Xia, S Ahmadi, C Bear, A Harris Cell and tissue research 381, 327-336, 2020 | 14 | 2020 |
