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Gregory Korbutt
Gregory Korbutt
Professor of Surgery, University of Alberta
Verified email at ualberta.ca
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Year
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
AMJ Shapiro, JRT Lakey, EA Ryan, GS Korbutt, E Toth, GL Warnock, ...
New England Journal of Medicine 343 (4), 230-238, 2000
67702000
International trial of the Edmonton protocol for islet transplantation
AMJ Shapiro, C Ricordi, BJ Hering, H Auchincloss, R Lindblad, ...
New England Journal of Medicine 355 (13), 1318-1330, 2006
24762006
Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol
EA Ryan, JRT Lakey, RV Rajotte, GS Korbutt, T Kin, S Imes, ...
Diabetes 50 (4), 710-719, 2001
11592001
Successful islet transplantation: continued insulin reserve provides long-term glycemic control
EA Ryan, JRT Lakey, BW Paty, S Imes, GS Korbutt, NM Kneteman, ...
Diabetes 51 (7), 2148-2157, 2002
10092002
Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages
RM Seaberg, SR Smukler, TJ Kieffer, G Enikolopov, Z Asghar, ...
Nature biotechnology 22 (9), 1115-1124, 2004
7402004
Generation of insulin-producing islet-like clusters from human embryonic stem cells
J Jiang, M Au, K Lu, A Eshpeter, G Korbutt, G Fisk, AS Majumdar
Stem cells 25 (8), 1940-1953, 2007
6612007
Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell–induced apoptosis
B Motyka, G Korbutt, MJ Pinkoski, JA Heibein, A Caputo, M Hobman, ...
Cell 103 (3), 491-500, 2000
5752000
Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways
K Cardona, GS Korbutt, Z Milas, J Lyon, J Cano, W Jiang, H Bello-Laborn, ...
Nature medicine 12 (3), 304-306, 2006
5532006
Glucose-dependent insulin release from genetically engineered K cells
AT Cheung, B Dayanandan, JT Lewis, GS Korbutt, RV Rajotte, ...
Science 290 (5498), 1959-1962, 2000
4442000
Large scale isolation, growth, and function of porcine neonatal islet cells.
GS Korbutt, JF Elliott, Z Ao, DK Smith, GL Warnock, RV Rajotte
The Journal of clinical investigation 97 (9), 2119-2129, 1996
4101996
Granzyme B: a natural born killer
SJ Lord, RV Rajotte, GS Korbutt, RC Bleackley
Immunological reviews 193 (1), 31-38, 2003
3882003
Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function.
DL Eizirik, GS Korbutt, C Hellerström
The Journal of clinical investigation 90 (4), 1263-1268, 1992
3831992
Cotransplantation of allogeneic islets with allogeneic testicular cell aggregates allows long-term graft survival without systemic immunosuppression
GS Korbutt, JF Elliott, RV Rajotte
Diabetes 46 (2), 317-322, 1997
2771997
Islet graft assessment in the Edmonton Protocol: implications for predicting long-term clinical outcome
CN Street, JRT Lakey, AMJ Shapiro, S Imes, RV Rajotte, EA Ryan, ...
Diabetes 53 (12), 3107-3114, 2004
2762004
Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction.
A Rabinovitch, W Suarez-Pinzon, K Strynadka, Q Ju, D Edelstein, ...
Diabetes 48 (6), 1223-1229, 1999
2711999
Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion
JRT Lakey, GL Warnock, AMJ Shapiro, GS Korbutt, Z Ao, NM Kneteman, ...
Cell transplantation 8 (3), 285-292, 1999
2541999
Insulin expressing cells from differentiated embryonic stem cells are not beta cells
S Sipione, A Eshpeter, JG Lyon, GS Korbutt, RC Bleackley
Diabetologia 47, 499-508, 2004
2512004
Expansion of mesenchymal stem cells from human pancreatic ductal epithelium
KL Seeberger, JM Dufour, AMJ Shapiro, JRT Lakey, RV Rajotte, ...
Laboratory investigation 86 (2), 141-153, 2006
2332006
Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts
KJ Potter, A Abedini, P Marek, AM Klimek, S Butterworth, M Driscoll, ...
Proceedings of the National Academy of Sciences 107 (9), 4305-4310, 2010
2022010
Testicular sertoli cells protect islet beta-cells from autoimmune destruction in NOD mice by a transforming growth factor-beta1-dependent mechanism.
W Suarez-Pinzon, GS Korbutt, R Power, J Hooton, RV Rajotte, ...
Diabetes 49 (11), 1810-1818, 2000
1772000
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