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James M. Angelo
James M. Angelo
MilliporeSigma
Verified email at milliporesigma.com
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Year
Biomanufacturing evolution from conventional to intensified processes for productivity improvement: a case study
J Xu, X Xu, C Huang, J Angelo, CL Oliveira, M Xu, X Xu, D Temel, J Ding, ...
MAbs 12 (1), 1770669, 2020
582020
Model assisted comparison of Protein A resins and multi-column chromatography for capture processes
D Baur, JM Angelo, S Chollangi, X Xu, T Müller-Späth, N Zhang, S Ghose, ...
Journal of biotechnology 285, 64-73, 2018
422018
Understanding mAb aggregation during low pH viral inactivation and subsequent neutralization
R Wälchli, M Ressurreição, S Vogg, F Feidl, J Angelo, X Xu, S Ghose, ...
Biotechnology and bioengineering 117 (3), 687-700, 2020
392020
Model‐assisted process characterization and validation for a continuous two‐column protein A capture process
D Baur, J Angelo, S Chollangi, T Müller‐Späth, X Xu, S Ghose, ZJ Li, ...
Biotechnology and bioengineering 116 (1), 87-98, 2019
322019
Scale‐up of twin‐column periodic counter‐current chromatography for MAb purification
J Angelo, J Pagano, T Müller‐Späth, K Mihlbachler, S Chollangi, X Xu, ...
Bioprocess international 16 (4), 28-37, 2018
282018
Characterization of cross-linked cellulosic ion-exchange adsorbents: 1. Structural properties
JM Angelo, A Cvetkovic, R Gantier, AM Lenhoff
Journal of Chromatography A 1319, 46-56, 2013
262013
Ionic strength-dependent changes in tentacular ion exchangers with variable ligand density. II. Functional properties
R Bhambure, JM Angelo, CM Gillespie, M Phillips, H Graalfs, AM Lenhoff
Journal of Chromatography A 1506, 55-64, 2017
252017
Determinants of protein elution rates from preparative ion-exchange adsorbents
JM Angelo, AM Lenhoff
Journal of Chromatography A 1440, 94-104, 2016
202016
Characterization of cross-linked cellulosic ion-exchange adsorbents: 2. Protein sorption and transport
JM Angelo, A Cvetkovic, R Gantier, AM Lenhoff
Journal of Chromatography A 1438, 100-112, 2016
202016
Model based strategies towards protein A resin lifetime optimization and supervision
F Feidl, MF Luna, M Podobnik, S Vogg, J Angelo, K Potter, E Wiggin, X Xu, ...
Journal of Chromatography A 1625, 461261, 2020
182020
Experimental design of the multicolumn countercurrent solvent gradient purification (MCSGP) unit for the separation of pegylated proteins
TK Kim, C Botti, J Angelo, X Xu, S Ghose, ZJ Li, M Morbidelli, ...
Industrial & Engineering Chemistry Research 60 (29), 10764-10776, 2021
162021
Characterization of dextran-grafted hydrophobic charge-induction resins: Structural properties, protein adsorption and transport
T Liu, JM Angelo, DQ Lin, AM Lenhoff, SJ Yao
Journal of Chromatography A 1517, 44-53, 2017
162017
Virus clearance validation across continuous capture chromatography
J Angelo, S Chollangi, T Müller‐Späth, S Jusyte, X Xu, S Ghose, Z Li
Biotechnology and Bioengineering 116 (9), 2275-2284, 2019
132019
Design and economic investigation of a Multicolumn Countercurrent Solvent Gradient Purification unit for the separation of an industrially relevant PEGylated protein
TK Kim, B Sechi, JJR Conde, J Angelo, X Xu, S Ghose, M Morbidelli, ...
Journal of Chromatography A 1681, 463487, 2022
62022
Continued insights into virus clearance validation across continuous capture chromatography
JM Angelo, K Potter, T Müller‐Späth, X Xu, ZJ Li, S Ghose
Biotechnology and Bioengineering 118 (9), 3604-3609, 2021
62021
Biomanufacturing evolution from conventional to intensified processes for productivity improvement: A case study. mAbs, 12 (1): 1770669
J Xu, X Xu, C Huang, J Angelo, CL Oliveira, M Xu, X Xu, D Temel, J Ding, ...
32020
Viral clearance validation across continuous capture chromatography
S Chollangi, J Angelo, X Xu, S Ghose, M Morbidelli
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018
22018
Mechanisms underlying protein sorption and transport within polysaccharide-based stationary phases for ion-exchange chromatography
JM Angelo
University of Delaware, 2016
22016
Role of the gradient slope during the product internal recycling for the multicolumn countercurrent solvent gradient purification of PEGylated proteins
TK Kim, AA Bham, I Fioretti, J Angelo, X Xu, S Ghose, M Morbidelli, ...
Journal of Chromatography A 1692, 463868, 2023
12023
Scale up design and optimization for an intensified downstream process utilizing multi-column operations
J Angelo, S Chollangi, J Pagano, D Baur, K Mihlbachler, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018
12018
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