Biomanufacturing evolution from conventional to intensified processes for productivity improvement: a case study J Xu, X Xu, C Huang, J Angelo, CL Oliveira, M Xu, X Xu, D Temel, J Ding, ... MAbs 12 (1), 1770669, 2020 | 58 | 2020 |
Model assisted comparison of Protein A resins and multi-column chromatography for capture processes D Baur, JM Angelo, S Chollangi, X Xu, T Müller-Späth, N Zhang, S Ghose, ... Journal of biotechnology 285, 64-73, 2018 | 42 | 2018 |
Understanding mAb aggregation during low pH viral inactivation and subsequent neutralization R Wälchli, M Ressurreição, S Vogg, F Feidl, J Angelo, X Xu, S Ghose, ... Biotechnology and bioengineering 117 (3), 687-700, 2020 | 39 | 2020 |
Model‐assisted process characterization and validation for a continuous two‐column protein A capture process D Baur, J Angelo, S Chollangi, T Müller‐Späth, X Xu, S Ghose, ZJ Li, ... Biotechnology and bioengineering 116 (1), 87-98, 2019 | 32 | 2019 |
Scale‐up of twin‐column periodic counter‐current chromatography for MAb purification J Angelo, J Pagano, T Müller‐Späth, K Mihlbachler, S Chollangi, X Xu, ... Bioprocess international 16 (4), 28-37, 2018 | 28 | 2018 |
Characterization of cross-linked cellulosic ion-exchange adsorbents: 1. Structural properties JM Angelo, A Cvetkovic, R Gantier, AM Lenhoff Journal of Chromatography A 1319, 46-56, 2013 | 26 | 2013 |
Ionic strength-dependent changes in tentacular ion exchangers with variable ligand density. II. Functional properties R Bhambure, JM Angelo, CM Gillespie, M Phillips, H Graalfs, AM Lenhoff Journal of Chromatography A 1506, 55-64, 2017 | 25 | 2017 |
Determinants of protein elution rates from preparative ion-exchange adsorbents JM Angelo, AM Lenhoff Journal of Chromatography A 1440, 94-104, 2016 | 20 | 2016 |
Characterization of cross-linked cellulosic ion-exchange adsorbents: 2. Protein sorption and transport JM Angelo, A Cvetkovic, R Gantier, AM Lenhoff Journal of Chromatography A 1438, 100-112, 2016 | 20 | 2016 |
Model based strategies towards protein A resin lifetime optimization and supervision F Feidl, MF Luna, M Podobnik, S Vogg, J Angelo, K Potter, E Wiggin, X Xu, ... Journal of Chromatography A 1625, 461261, 2020 | 18 | 2020 |
Experimental design of the multicolumn countercurrent solvent gradient purification (MCSGP) unit for the separation of pegylated proteins TK Kim, C Botti, J Angelo, X Xu, S Ghose, ZJ Li, M Morbidelli, ... Industrial & Engineering Chemistry Research 60 (29), 10764-10776, 2021 | 16 | 2021 |
Characterization of dextran-grafted hydrophobic charge-induction resins: Structural properties, protein adsorption and transport T Liu, JM Angelo, DQ Lin, AM Lenhoff, SJ Yao Journal of Chromatography A 1517, 44-53, 2017 | 16 | 2017 |
Virus clearance validation across continuous capture chromatography J Angelo, S Chollangi, T Müller‐Späth, S Jusyte, X Xu, S Ghose, Z Li Biotechnology and Bioengineering 116 (9), 2275-2284, 2019 | 13 | 2019 |
Design and economic investigation of a Multicolumn Countercurrent Solvent Gradient Purification unit for the separation of an industrially relevant PEGylated protein TK Kim, B Sechi, JJR Conde, J Angelo, X Xu, S Ghose, M Morbidelli, ... Journal of Chromatography A 1681, 463487, 2022 | 6 | 2022 |
Continued insights into virus clearance validation across continuous capture chromatography JM Angelo, K Potter, T Müller‐Späth, X Xu, ZJ Li, S Ghose Biotechnology and Bioengineering 118 (9), 3604-3609, 2021 | 6 | 2021 |
Biomanufacturing evolution from conventional to intensified processes for productivity improvement: A case study. mAbs, 12 (1): 1770669 J Xu, X Xu, C Huang, J Angelo, CL Oliveira, M Xu, X Xu, D Temel, J Ding, ... | 3 | 2020 |
Viral clearance validation across continuous capture chromatography S Chollangi, J Angelo, X Xu, S Ghose, M Morbidelli ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | 2 | 2018 |
Mechanisms underlying protein sorption and transport within polysaccharide-based stationary phases for ion-exchange chromatography JM Angelo University of Delaware, 2016 | 2 | 2016 |
Role of the gradient slope during the product internal recycling for the multicolumn countercurrent solvent gradient purification of PEGylated proteins TK Kim, AA Bham, I Fioretti, J Angelo, X Xu, S Ghose, M Morbidelli, ... Journal of Chromatography A 1692, 463868, 2023 | 1 | 2023 |
Scale up design and optimization for an intensified downstream process utilizing multi-column operations J Angelo, S Chollangi, J Pagano, D Baur, K Mihlbachler, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | 1 | 2018 |