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Jeffrey P MacKeigan
Jeffrey P MacKeigan
Professor and Assistant Dean, Michigan State University
Verified email at msu.edu - Homepage
Title
Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13053*2021
Activation of a metabolic gene regulatory network downstream of mTOR complex 1
K Düvel, JL Yecies, S Menon, P Raman, AI Lipovsky, AL Souza, ...
Molecular cell 39 (2), 171-183, 2010
21782010
Bidirectional transport of amino acids regulates mTOR and autophagy
P Nicklin, P Bergman, B Zhang, E Triantafellow, H Wang, B Nyfeler, ...
Cell 136 (3), 521-534, 2009
19342009
Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
JP MacKeigan, LO Murphy, J Blenis
Nature cell biology 7 (6), 591-600, 2005
7202005
A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration
LO Murphy, JP MacKeigan, J Blenis
Molecular and cellular biology 24 (1), 144-153, 2004
4262004
MEK inhibition enhances paclitaxel-induced tumor apoptosis
JP MacKeigan, TS Collins, JPY Ting
Journal of Biological Chemistry 275 (50), 38953-38956, 2000
2832000
Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors
BA Ballif, PP Roux, SA Gerber, JP MacKeigan, J Blenis, SP Gygi
Proceedings of the National Academy of Sciences 102 (3), 667-672, 2005
2672005
Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIα
JP MacKeigan, CM Clements, JD Lich, RM Pope, Y Hod, JPY Ting
Cancer research 63 (20), 6928-6934, 2003
2292003
Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing
MS Stark, SL Woods, MG Gartside, VF Bonazzi, K Dutton-Regester, ...
Nature genetics 44 (2), 165-169, 2012
2182012
The genomic landscape of tuberous sclerosis complex
KR Martin, W Zhou, MJ Bowman, J Shih, KS Au, KE Dittenhafer-Reed, ...
Nature communications 8 (1), 15816, 2017
1872017
Mitochondria in cancer: at the crossroads of life and death
VC Fogg, NJ Lanning, JP MacKeigan
Chinese journal of cancer 30 (8), 526, 2011
1842011
Differentiating the mTOR inhibitors everolimus and sirolimus in the treatment of tuberous sclerosis complex
JP MacKeigan, DA Krueger
Neuro-oncology 17 (12), 1550-1559, 2015
1672015
Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities
NJ Lanning, JP Castle, SJ Singh, AN Leon, EA Tovar, A Sanghera, ...
Cancer & metabolism 5, 1-14, 2017
1592017
Biodistribution of radiolabeled lipid–DNA complexes and DNA in mice
R Niven, R Pearlman, T Wedeking, J Mackeigan, P Noker, ...
Journal of pharmaceutical sciences 87 (11), 1292-1299, 1998
1561998
STAT3 is activated by JAK2 independent of key oncogenic driver mutations in non-small cell lung carcinoma
BD Looyenga, D Hutchings, I Cherni, C Kingsley, GJ Weiss, ...
PloS one 7 (2), e30820, 2012
1322012
Spatially separate docking sites on ERK2 regulate distinct signaling events in vivo
CA Dimitri, W Dowdle, JP MacKeigan, J Blenis, LO Murphy
Current Biology 15 (14), 1319-1324, 2005
1322005
Graded mitogen-activated protein kinase activity precedes switch-like c-Fos induction in mammalian cells
JP MacKeigan, LO Murphy, CA Dimitri, J Blenis
Molecular and cellular biology 25 (11), 4676-4682, 2005
1262005
Mitochondrial morphological features are associated with fission and fusion events
LM Westrate, JA Drocco, KR Martin, WS Hlavacek, JP MacKeigan
PloS one 9 (4), e95265, 2014
1222014
A potent and selective ULK1 inhibitor suppresses autophagy and sensitizes cancer cells to nutrient stress
KR Martin, SL Celano, AR Solitro, H Gunaydin, M Scott, RC O'Hagan, ...
Iscience 8, 74-84, 2018
1162018
Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib
ML Goodall, T Wang, KR Martin, MG Kortus, AL Kauffman, JM Trent, ...
Autophagy 10 (6), 1120-1136, 2014
1162014
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Articles 1–20