Linda Rieswijk
Linda Rieswijk
Maastricht Institute of Data Science
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WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research
DN Slenter, M Kutmon, K Hanspers, A Riutta, J Windsor, N Nunes, ...
Nucleic acids research 46 (D1), D661-D667, 2018
Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification
MA La Merrill, LN Vandenberg, MT Smith, W Goodson, P Browne, ...
Nature Reviews Endocrinology, 2019
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ...
Nature communications 10 (1), 2674, 2019
Aflatoxin B1 induces persistent epigenomic effects in primary human hepatocytes associated with hepatocellular carcinoma
L Rieswijk, SMH Claessen, O Bekers, M van Herwijnen, DHJ Theunissen, ...
Toxicology 350, 31-39, 2016
The key characteristics of carcinogens: relationship to the hallmarks of cancer, relevant biomarkers, and assays to measure them
MT Smith, KZ Guyton, N Kleinstreuer, A Borrel, A Cardenas, WA Chiu, ...
Cancer Epidemiology, Biomarkers & Prevention 29 (10), 1887-1903, 2020
Proposed key characteristics of female reproductive toxicants as an approach for organizing and evaluating mechanistic data in hazard assessment
U Luderer, B Eskenazi, R Hauser, KS Korach, CM McHale, F Moran, ...
Environmental health perspectives 127 (7), 075001, 2019
A data fusion pipeline for generating and enriching adverse outcome pathway descriptions
P Nymark, L Rieswijk, F Ehrhart, N Jeliazkova, G Tsiliki, H Sarimveis, ...
Toxicological Sciences 162 (1), 264-275, 2018
Key characteristics approach to carcinogenic hazard identification
KZ Guyton, L Rieswijk, A Wang, WA Chiu, MT Smith
Chemical research in toxicology 31 (12), 1290-1292, 2018
Formaldehyde and brain disorders: a meta-analysis and bioinformatics approach
I Rana, L Rieswijk, C Steinmaus, L Zhang
Neurotoxicity research 39, 924-948, 2021
Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women
JYY Wong, H Zhang, CA Hsiung, K Shiraishi, K Yu, K Matsuo, MP Wong, ...
Genomics 112 (2), 1223-1232, 2020
A state-of-the-science review of arsenic’s effects on glucose homeostasis in experimental models
F Castriota, L Rieswijk, S Dahlberg, MA La Merrill, C Steinmaus, MT Smith, ...
Environmental health perspectives 128 (1), 016001, 2020
Human exposure to trichloroethylene is associated with increased variability of blood DNA methylation that is enriched in genes and pathways related to autoimmune disease and …
RV Phillips, L Rieswijk, AE Hubbard, R Vermeulen, J Zhang, W Hu, L Li, ...
Epigenetics 14 (11), 1112-1124, 2019
Evaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes
L Rieswijk, KJJ Brauers, MLJ Coonen, SGJ Van Breda, DGJ Jennen, ...
Mutagenesis 30 (6), 771-784, 2015
Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and …
L Rieswijk, KJJ Brauers, MLJ Coonen, DGJ Jennen, SGJ van Breda, ...
Mutagenesis 31 (5), 603-615, 2016
Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating …
L Rieswijk, D Lizarraga, KJJ Brauers, JCS Kleinjans, JHM van Delft
Mutagenesis 29 (1), 17-26, 2014
InContext: curation of medical context for drug indications
K Moodley, L Rieswijk, TI Oprea, M Dumontier
Journal of biomedical semantics 12, 1-15, 2021
eNanoMapper–A database and ontology framework for design and safety assessment of nanomaterials
G Kilic, B Fadeel, L Farcal, H Sarimveis, P Doganis, G Drakakis, G Tsiliki, ...
Toxicology Letters 258 (September), S118-S119, 2016
TAPS Responsibility Matrix: A tool for responsible data science by design
V Urovi, R Celebi, C Sun, L Rieswijk, M Erard, A Yilmaz, K Moodley, ...
arXiv preprint arXiv:2302.01041, 2023
An approach to the proposal of drug combination for cancer therapy using a pathway data connectivity approach
R Miller, S Muraru, AB Malpartida, J Low, MP de Almeida, B van Engelen, ...
Persistent transcriptional responses show the involvement of feed-forward control in a repeated dose toxicity study
TM Souza, L Rieswijk, T van den Beucken, J Kleinjans, D Jennen
Toxicology 375, 58-63, 2017
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