Florian Heigwer, PhD
Florian Heigwer, PhD
Post-Doc, German Cancer research Center, University Heidelberg
Verified email at dkfz.de - Homepage
Title
Cited by
Cited by
Year
E-CRISP: fast CRISPR target site identification
F Heigwer, G Kerr, M Boutros
Nature methods 11 (2), 122, 2014
4562014
Microscopy-based high-content screening
M Boutros, F Heigwer, C Laufer
Cell 163 (6), 1314-1325, 2015
1682015
Data-analysis strategies for image-based cell profiling
JC Caicedo, S Cooper, F Heigwer, S Warchal, P Qiu, C Molnar, ...
Nature methods 14 (9), 849, 2017
1562017
E-TALEN: a web tool to design TALENs for genome engineering
F Heigwer, G Kerr, N Walther, K Glaeser, O Pelz, M Breinig, M Boutros
Nucleic acids research 41 (20), e190-e190, 2013
552013
CRISPR library designer (CLD): software for multispecies design of single guide RNA libraries
F Heigwer, T Zhan, M Breinig, J Winter, D Brügemann, S Leible, ...
Genome biology 17 (1), 55, 2016
382016
GenomeCRISPR-a database for high-throughput CRISPR/Cas9 screens
B Rauscher, F Heigwer, M Breinig, J Winter, M Boutros
Nucleic acids research, gkw997, 2016
382016
Machine learning and image-based profiling in drug discovery
C Scheeder, F Heigwer, M Boutros
Current opinion in systems biology 10, 43-52, 2018
342018
caRpools: an R package for exploratory data analysis and documentation of pooled CRISPR/Cas9 screens
J Winter, M Breinig, F Heigwer, D Brügemann, S Leible, O Pelz, T Zhan, ...
Bioinformatics 32 (4), 632-634, 2016
292016
RNA Interference (RNAi) Screening in Drosophila
F Heigwer, F Port, M Boutros
Genetics 208 (3), 853-874, 2018
282018
Toward an integrated map of genetic interactions in cancer cells
B Rauscher, F Heigwer, L Henkel, T Hielscher, O Voloshanenko, ...
Molecular Systems Biology 14 (2), 2018
282018
Microarray‐based kinetic colorimetric detection for quantitative multiplex protein phosphorylation analysis
P Holenya, I Kitanovic, F Heigwer, S Wölfl
Proteomics 11 (10), 2129-2133, 2011
132011
Acetic acid treatment in S. cerevisiae creates significant energy deficiency and nutrient starvation that is dependent on the activity of the mitochondrial transcriptional …
A Kitanovic, F Bonowski, F Heigwer, P Ruoff, I Kitanovic, C Ungewiss, ...
Frontiers in oncology 2, 118, 2012
122012
Time-resolved mapping of genetic interactions to model rewiring of signaling pathways
F Heigwer, C Scheeder, T Miersch, B Schmitt, C Blass, MVP Jamnani, ...
Elife 7, e40174, 2018
92018
CRISPRAnalyzeR: Interactive analysis, annotation and documentation of pooled CRISPR screens
J Winter, M Schwering, O Pelz, B Rauscher, T Zhan, F Heigwer, M Boutros
BioRxiv, 109967, 2017
82017
A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila
F Port, C Strein, M Stricker, B Rauscher, F Heigwer, J Zhou, ...
Elife 9, 2020
72020
KOMA: ELISA-microarray calibration and data analysis based on kinetic signal amplification
P Holenya, F Heigwer, S Wölfl
Journal of immunological methods 380 (1-2), 10-15, 2012
72012
Single-cell phenotyping of human induced pluripotent stem cells by high-throughput imaging
HC Volz, F Heigwer, T Wüest, M Galach, J Utikal, HA Katus, M Boutros
bioRxiv, 026955, 2015
42015
HTSvis: a web app for exploratory data analysis and visualization of arrayed high-throughput screens
C Scheeder, F Heigwer, M Boutros
Bioinformatics 33 (18), 2960-2962, 2017
32017
4Pi Nanoscopy parallelized by line scanning
F Curdt
22013
Lineage specific core-regulatory circuits determine gene essentiality in cancer cells
B Rauscher, L Henkel, F Heigwer, M Boutros
bioRxiv, 609552, 2019
2019
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Articles 1–20