Amit Deshwar
Amit Deshwar
Verified email at utoronto.ca
TitleCited byYear
PhyloWGS: reconstructing subclonal composition and evolution from whole-genome sequencing of tumors
AG Deshwar, S Vembu, CK Yung, GH Jang, L Stein, Q Morris
Genome biology 16 (1), 35, 2015
2022015
Inferring clonal evolution of tumors from single nucleotide somatic mutations
W Jiao, S Vembu, AG Deshwar, L Stein, Q Morris
BMC bioinformatics 15 (1), 35, 2014
1862014
Computational purification of individual tumor gene expression profiles leads to significant improvements in prognostic prediction
G Quon, S Haider, AG Deshwar, A Cui, PC Boutros, Q Morris
Genome medicine 5 (3), 29, 2013
662013
SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans
EK Allen, AG Randolph, T Bhangale, P Dogra, M Ohlson, CM Oshansky, ...
Nature medicine 23 (8), 975, 2017
552017
Correction of a splicing defect in a mouse model of congenital muscular dystrophy type 1A using a homology-directed-repair-independent mechanism
DU Kemaladewi, E Maino, E Hyatt, H Hou, M Ding, KM Place, X Zhu, ...
Nature medicine 23 (8), 984, 2017
422017
The evolutionary history of 2,658 cancers
M Gerstung, C Jolly, I Leshchiner, SC Dentro, SG Rosado, D Rosebrock, ...
BioRxiv, 161562, 2018
312018
D-mannose induces regulatory T cells and suppresses immunopathology
D Zhang, C Chia, X Jiao, W Jin, S Kasagi, R Wu, JE Konkel, ...
Nature Medicine 23 (9), 1036, 2017
282017
PLIDA: cross-platform gene expression normalization using perturbed topic models
AG Deshwar, Q Morris
Bioinformatics 30 (7), 956-961, 2014
192014
ISOpureR: an R implementation of a computational purification algorithm of mixed tumour profiles
CV Anghel, G Quon, S Haider, F Nguyen, AG Deshwar, QD Morris, ...
BMC bioinformatics 16 (1), 156, 2015
182015
COSSMO: predicting competitive alternative splice site selection using deep learning
H Bretschneider, S Gandhi, AG Deshwar, K Zuberi, BJ Frey
Bioinformatics 34 (13), i429-i437, 2018
142018
Portraits of genetic intra-tumour heterogeneity and subclonal selection across cancer types
SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ...
BioRxiv, 312041, 2018
132018
Identifying cancer specific functionally relevant miRNAs from gene expression and miRNA-to-gene networks using regularized regression
AM Mezlini, B Wang, A Deshwar, Q Morris, A Goldenberg
PloS one 8 (10), 2013
132013
The evolutionary history of 2,658 cancers
M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, ...
Nature 578 (7793), 122-128, 2020
122020
Portraits of genetic intra-tumour heterogeneity and subclonal selection across cancer types. bioRxiv. 2018
SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ...
URL https://www. biorxiv. org/content/10.1101/312041v4, 0
7
Relapsing-remitting multiple sclerosis classification using elastic net logistic regression on gene expression data
C Zhao, AG Deshwar, Q Morris
Systems Biomedicine 1 (4), 247-253, 2013
62013
TrackSig: reconstructing evolutionary trajectories of mutation signature exposure
Y Rubanova, R Li, J Wintersinger, N Sahin, A Deshwar, Q Morris, ...
BioRxiv, 260471, 2018
52018
Reconstructing subclonal composition and evolution from whole genome sequencing of tumors
AG Deshwar, S Vembu, CK Yung, GH Jang, L Stein, Q Morris
arXiv preprint arXiv:1406.7250, 2014
52014
Pervasive intra-tumour heterogeneity and subclonal selection across cancer types
S Dentro, I Leshchiner, K Haase, J Wintersinger, A Deshwar, M Tarabichi, ...
Cancer Research 78 (13 Supplement), 3000-3000, 2018
32018
A community effort to create standards for evaluating tumor subclonal reconstruction
A Salcedo, M Tarabichi, SMG Espiritu, AG Deshwar, M David, NM Wilson, ...
Nature Biotechnology 38 (1), 97-107, 2020
22020
Abstract B2-59: PhyloSpan: Using multi-mutation reads to resolve subclonal architectures from heterogeneous tumor samples
AG Deshwar, L Boyles, J Wintersinger, PC Boutros, YW Teh, Q Morris
Cancer Research 75 (22 Supplement 2), B2-59-B2-59, 2015
22015
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Articles 1–20