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Mei Zhen
Mei Zhen
LTRI, University of Toronto
Verified email at lunenfeld.ca - Homepage
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Year
ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function
T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, ...
Neuron 88 (4), 678-690, 2015
8102015
The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans
M Zhen, Y Jin
Nature 401 (6751), 371-375, 1999
4491999
Connectomes across development reveal principles of brain maturation
D Witvliet, B Mulcahy, JK Mitchell, Y Meirovitch, DR Berger, Y Wu, Y Liu, ...
Nature 596 (7871), 257-261, 2021
2812021
Proprioceptive coupling within motor neurons drives C. elegans forward locomotion
Q Wen, MD Po, E Hulme, S Chen, X Liu, SW Kwok, M Gershow, AM Leifer, ...
neuron 76 (4), 750-761, 2012
2792012
Regulation of presynaptic terminal organization by C. elegans RPM-1, a putative guanine nucleotide exchanger with a RING-H2 finger domain
M Zhen, X Huang, B Bamber, Y Jin
Neuron 26 (2), 331-343, 2000
2792000
An imbalancing act: gap junctions reduce the backward motor circuit activity to bias C. elegans for forward locomotion
T Kawano, MD Po, S Gao, G Leung, WS Ryu, M Zhen
Neuron 72 (4), 572-586, 2011
2742011
An SCF-like ubiquitin ligase complex that controls presynaptic differentiation
EH Liao, W Hung, B Abrams, M Zhen
Nature 430 (6997), 345-350, 2004
2672004
Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein
JA Calarco, S Superina, D O'Hanlon, M Gabut, B Raj, Q Pan, U Skalska, ...
Cell 138 (5), 898-910, 2009
2492009
Pan-neuronal imaging in roaming Caenorhabditis elegans
V Venkatachalam, N Ji, X Wang, C Clark, JK Mitchell, M Klein, CJ Tabone, ...
Proceedings of the National Academy of Sciences 113 (8), E1082-E1088, 2016
2242016
Optogenetic analysis of synaptic function
JF Liewald, M Brauner, GJ Stephens, M Bouhours, C Schultheis, M Zhen, ...
Nature methods 5 (10), 895-902, 2008
2232008
A 3D culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction
M Afshar Bakooshli, ES Lippmann, B Mulcahy, N Iyer, CT Nguyen, K Tung, ...
Elife 8, e44530, 2019
2152019
The SAD-1 kinase regulates presynaptic vesicle clustering and axon termination
JG Crump, M Zhen, Y Jin, CI Bargmann
Neuron 29 (1), 115-129, 2001
2122001
Hierarchical assembly of presynaptic components in defined C. elegans synapses
MR Patel, EK Lehrman, VY Poon, JG Crump, M Zhen, CI Bargmann, ...
Nature neuroscience 9 (12), 1488-1498, 2006
2002006
C. elegans locomotion: small circuits, complex functions
M Zhen, ADT Samuel
Current opinion in neurobiology 33, 117-126, 2015
1962015
Genome-wide analysis of alternative splicing in Caenorhabditis elegans
AK Ramani, JA Calarco, Q Pan, S Mavandadi, Y Wang, AC Nelson, ...
Genome research 21 (2), 342-348, 2011
1922011
Action potentials drive body wall muscle contractions in Caenorhabditis elegans
S Gao, M Zhen
Proceedings of the National Academy of Sciences 108 (6), 2557-2562, 2011
1662011
Real-time volumetric reconstruction of biological dynamics with light-field microscopy and deep learning
Z Wang, L Zhu, H Zhang, G Li, C Yi, Y Li, Y Yang, Y Ding, M Zhen, S Gao, ...
Nature methods 18 (5), 551-556, 2021
1422021
A putative cation channel, NCA-1, and a novel protein, UNC-80, transmit neuronal activity in C. elegans
E Yeh, S Ng, M Zhang, M Bouhours, Y Wang, M Wang, W Hung, K Aoyagi, ...
PLoS biology 6 (3), e55, 2008
1292008
The presynaptic dense projection of the Caenorhabiditis elegans cholinergic neuromuscular junction localizes synaptic vesicles at the active zone through SYD-2/Liprin and UNC …
C Stigloher, H Zhan, M Zhen, J Richmond, JL Bessereau
Journal of Neuroscience 31 (12), 4388-4396, 2011
1282011
ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism
T Murakami, SP Yang, L Xie, T Kawano, D Fu, A Mukai, C Bohm, F Chen, ...
Human molecular genetics 21 (1), 1-9, 2012
1272012
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