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Darren H. Freed
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Cardiac fibroblast to myofibroblast differentiation in vivo and in vitro: expression of focal adhesion components in neonatal and adult rat ventricular myofibroblasts
JJ Santiago, AL Dangerfield, SG Rattan, KL Bathe, RH Cunnington, ...
Developmental dynamics 239 (6), 1573-1584, 2010
3462010
Survival after pulmonary thromboendarterectomy: effect of residual pulmonary hypertension
DH Freed, BM Thomson, M Berman, SSL Tsui, J Dunning, KK Sheares, ...
The Journal of thoracic and cardiovascular surgery 141 (2), 383-387, 2011
2902011
Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients
ED Michelakis, V Gurtu, L Webster, G Barnes, G Watson, L Howard, ...
Science translational medicine 9 (413), eaao4583, 2017
2412017
K+ currents regulate the resting membrane potential, proliferation, and contractile responses in ventricular fibroblasts and myofibroblasts
L Chilton, S Ohya, D Freed, E George, V Drobic, Y Shibukawa, ...
American Journal of Physiology-Heart and Circulatory Physiology 288 (6 …, 2005
2262005
Functional assessment and transplantation of the donor heart after circulatory death
SJ Messer, RG Axell, S Colah, PA White, M Ryan, AA Page, B Parizkova, ...
The Journal of Heart and Lung Transplantation 35 (12), 1443-1452, 2016
2122016
Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts
S Ghavami, RH Cunnington, S Gupta, B Yeganeh, KL Filomeno, ...
Cell death & disease 6 (3), e1696-e1696, 2015
1902015
Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease
B Yeganeh, E Wiechec, SR Ande, P Sharma, AR Moghadam, M Post, ...
Pharmacology & therapeutics 143 (1), 87-110, 2014
1832014
Adipose-derived stem cells are an effective cell candidate for treatment of heart failure: an MR imaging study of rat hearts
L Wang, J Deng, W Tian, B Xiang, T Yang, G Li, J Wang, M Gruwel, ...
American journal of physiology-heart and circulatory physiology 297 (3 …, 2009
1682009
Short-term mechanical circulatory support for recovery from acute right ventricular failure: clinical outcomes
AW Cheung, CW White, MK Davis, DH Freed
The Journal of Heart and Lung Transplantation 33 (8), 794-799, 2014
1502014
Extracorporeal lung support for patients who had severe respiratory failure secondary to influenza A (H1N1) 2009 infection in Canada
DH Freed, D Henzler, CW White, R Fowler, R Zarychanski, J Hutchison, ...
Canadian journal of anaesthesia 57 (3), 240, 2010
1382010
Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts
S Ghavami, B Yeganeh, GL Stelmack, HH Kashani, P Sharma, ...
Cell death & disease 3 (6), e330-e330, 2012
1362012
Emerging evidence for the role of cardiotrophin-1 in cardiac repair in the infarcted heart
DH Freed, RH Cunnington, AL Dangerfield, JS Sutton, IMC Dixon
Cardiovascular research 65 (4), 782-792, 2005
1332005
Cardiotrophin-1: expression in experimental myocardial infarction and potential role in post-MI wound healing
DH Freed, MC Moon, AM Borowiec, SC Jones, P Zahradka, IMC Dixon
Molecular and cellular biochemistry 254, 247-256, 2003
1132003
A cardioprotective preservation strategy employing ex vivo heart perfusion facilitates successful transplant of donor hearts after cardiocirculatory death
CW White, A Ali, D Hasanally, B Xiang, Y Li, P Mundt, M Lytwyn, S Colah, ...
The Journal of Heart and Lung Transplantation 32 (7), 734-743, 2013
1002013
Intermediate-term outcomes of the arterial switch operation for transposition of great arteries in neonates: alive but well?
DH Freed, CMT Robertson, RS Sauve, AR Joffe, IM Rebeyka, DB Ross, ...
The Journal of Thoracic and Cardiovascular Surgery 132 (4), 845-852. e2, 2006
1002006
Maintaining the permanence principle for death during in situ normothermic regional perfusion for donation after circulatory death organ recovery: a United Kingdom and Canadian …
A Manara, SD Shemie, S Large, A Healey, A Baker, M Badiwala, ...
American Journal of Transplantation 20 (8), 2017-2025, 2020
952020
Coronary artery bypass surgery improves outcomes in patients with diabetes and left ventricular dysfunction
J Nagendran, SJ Bozso, CM Norris, FA McAlister, JJ Appoo, MC Moon, ...
Journal of the American College of Cardiology 71 (8), 819-827, 2018
912018
A whole blood–based perfusate provides superior preservation of myocardial function during ex vivo heart perfusion
CW White, D Hasanally, P Mundt, Y Li, B Xiang, J Klein, A Müller, E Avery, ...
The Journal of Heart and Lung Transplantation 34 (1), 113-121, 2015
902015
Influenza myocarditis and myositis: case presentation and review of the literature
K Kumar, M Guirgis, S Zieroth, E Lo, AH Menkis, RC Arora, DH Freed
Canadian Journal of Cardiology 27 (4), 514-522, 2011
882011
Transplantation of hearts donated after circulatory death
CW White, SJ Messer, SR Large, J Conway, DH Kim, DJ Kutsogiannis, ...
Frontiers in cardiovascular medicine 5, 8, 2018
842018
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