| Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity AG Tsai, H Lu, SC Raghavan, M Muschen, CL Hsieh, MR Lieber Cell 135 (6), 1130-1142, 2008 | 286 | 2008 |
| Nonhomologous DNA end joining (NHEJ) and chromosomal translocations in humans MR Lieber, J Gu, H Lu, N Shimazaki, AG Tsai Genome stability and human diseases, 279-296, 2010 | 201 | 2010 |
| Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence J Gu, H Lu, AG Tsai, K Schwarz, MR Lieber Nucleic acids research 35 (17), 5755-5762, 2007 | 182 | 2007 |
| H3K4me3 stimulates the V (D) J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: implications for translocations N Shimazaki, AG Tsai, MR Lieber Molecular cell 34 (5), 535-544, 2009 | 134 | 2009 |
| Mechanisms of chromosomal rearrangement in the human genome AG Tsai, MR Lieber BMC genomics 11 (Suppl 1), S1, 2010 | 123 | 2010 |
| Targeted next-generation sequencing identifies a subset of idiopathic hypereosinophilic syndrome with features similar to chronic eosinophilic leukemia, not otherwise specified SA Wang, W Tam, AG Tsai, DA Arber, RP Hasserjian, JT Geyer, TI George, ... Modern Pathology 29 (8), 854-864, 2016 | 111 | 2016 |
| Hotpatch: a statistical a pproach to finding biologically relevant features on protein surfaces FK Pettit, E Bare, A Tsai, JU Bowie Journal of molecular biology 369 (3), 863-879, 2007 | 101 | 2007 |
| IgH partner breakpoint sequences provide evidence that AID initiates t (11; 14) and t (8; 14) chromosomal breaks in mantle cell and Burkitt lymphomas HA Greisman, Z Lu, AG Tsai, TC Greiner, HS Yi, MR Lieber Blood, The Journal of the American Society of Hematology 120 (14), 2864-2867, 2012 | 80 | 2012 |
| Bone marrow morphology is a strong discriminator between chronic eosinophilic leukemia, not otherwise specified and reactive idiopathic hypereosinophilic syndrome SA Wang, RP Hasserjian, W Tam, AG Tsai, JT Geyer, TI George, K Foucar, ... Haematologica 102 (8), 1352, 2017 | 67 | 2017 |
| Impact of somatic and germline mutations on the outcome of systemic mastocytosis JI Muñoz-González, M Jara-Acevedo, I Alvarez-Twose, JD Merker, ... Blood advances 2 (21), 2814-2828, 2018 | 50 | 2018 |
| Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites AG Tsai, AE Engelhart, MH Ma'mon, SI Houston, NV Hud, IS Haworth, ... Journal of biological chemistry 284 (11), 7157-7164, 2009 | 50 | 2009 |
| BCL6 breaks occur at different AID sequence motifs in Ig–BCL6 and non-Ig–BCL6 rearrangements Z Lu, AG Tsai, T Akasaka, H Ohno, Y Jiang, AM Melnick, HA Greisman, ... Blood, The Journal of the American Society of Hematology 121 (22), 4551-4554, 2013 | 41 | 2013 |
| Unexpected complexity at breakpoint junctions in phenotypically normal individuals and mechanisms involved in generating balanced translocations t (1; 22)(p36; q13) M Gajecka, AJ Gentles, A Tsai, D Chitayat, KL Mackay, CD Glotzbach, ... Genome research 18 (11), 1733-1742, 2008 | 37 | 2008 |
| Multiplexed Single-Cell Morphometry for Hematopathology Diagnostics AG Tsai, DR Glass, M Juntilla, FJ Hartmann, JS Oak, S Fernandez-Pol, ... Nature Medicine 26 (3), 408-417, 2020 | 35 | 2020 |
| Analysis of non‐B DNA structure at chromosomal sites in the mammalian genome SC Raghavan, A Tsai, CL Hsieh, MR Lieber Methods in enzymology 409, 301-316, 2006 | 27 | 2006 |
| The t (14; 18)(q32; q21)/IGH-MALT1 translocation in MALT lymphomas is a CpG-type translocation, but the t (11; 18)(q21; q21)/API2-MALT1 translocation in MALT lymphomas is not AG Tsai, Z Lu, MR Lieber Blood, The Journal of the American Society of Hematology 115 (17), 3640-3641, 2010 | 26 | 2010 |
| t (X; 14)(p22; q32)/t (Y; 14)(p11; q32) CRLF2-IGH translocations from human B-lineage ALLs involve CpG-type breaks at CRLF2, but CRLF2/P2RY8 intrachromosomal deletions do not AG Tsai, A Yoda, DM Weinstock, MR Lieber Blood, The Journal of the American Society of Hematology 116 (11), 1993-1994, 2010 | 24 | 2010 |
| Both CpG Methylation and Activation-Induced Deaminase Are Required for the Fragility of the Human bcl-2 Major Breakpoint Region: Implications for the Timing of … X Cui, Z Lu, A Kurosawa, L Klemm, AT Bagshaw, AG Tsai, N Gemmell, ... Molecular and cellular biology 33 (5), 947-957, 2013 | 22 | 2013 |
| Heterogeneity and randomness of DNA methylation patterns in human embryonic stem cells AG Tsai, DM Chen, M Lin, JCF Hsieh, CY Okitsu, A Taghva, D Shibata, ... DNA and cell biology 31 (6), 893-907, 2012 | 11 | 2012 |
| Human lymphoid translocation fragile zones are hypomethylated and have accessible chromatin Z Lu, MR Lieber, AG Tsai, CE Pardo, M Müschen, MP Kladde, CL Hsieh Molecular and cellular biology 35 (7), 1209-1222, 2015 | 9 | 2015 |
