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Polyxeni Alexiou
Polyxeni Alexiou
Aristotle University of Thessaloniki, NCSR Demokritos
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Year
Aldose reductase enzyme and its implication to major health problems of the 21st century
P Alexiou, K Pegklidou, M Chatzopoulou, I Nicolaou, VJ Demopoulos
Current medicinal chemistry 16 (6), 734-752, 2009
2682009
RAGE: a multi-ligand receptor unveiling novel insights in health and disease
P Alexiou, M Chatzopoulou, K Pegklidou, VJ Demopoulos
Current medicinal chemistry 17 (21), 2232-2252, 2010
1762010
Curcumin derivatives as photosensitizers in photodynamic therapy: photophysical properties and in vitro studies with prostate cancer cells
KT Kazantzis, K Koutsonikoli, B Mavroidi, M Zachariadis, P Alexiou, ...
Photochemical & Photobiological Sciences 19, 193-206, 2020
962020
A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity
P Alexiou, VJ Demopoulos
Journal of medicinal chemistry 53 (21), 7756-7766, 2010
702010
The aldose reductase inhibitory capacity of Sorbus domestica fruit extracts depends on their phenolic content and may be useful for the control of diabetic complications
A Termentzi, P Alexiou, VJ Demopoulos, E Kokkalou
Die Pharmazie-An International Journal of Pharmaceutical Sciences 63 (9 …, 2008
622008
Synthesis of hydroxyapatite, β-tricalcium phosphate and biphasic calcium phosphate particles to act as local delivery carriers of curcumin: loading, release and in vitro studies
D Xidaki, P Agrafioti, D Diomatari, A Kaminari, E Tsalavoutas-Psarras, ...
Materials 11 (4), 595, 2018
522018
Novel aldose reductase inhibitors: a patent survey (2006–present)
M Chatzopoulou, P Alexiou, E Kotsampasakou, VJ Demopoulos
Expert opinion on therapeutic patents 22 (11), 1303-1323, 2012
512012
Novel curcumin derivatives as P-glycoprotein inhibitors: Molecular modeling, synthesis and sensitization of multidrug resistant cells to doxorubicin
M Sagnou, FN Novikov, ES Ivanova, P Alexiou, VS Stroylov, IY Titov, ...
European Journal of Medicinal Chemistry 198, 112331, 2020
372020
Rationally designed less toxic SPD‐304 analogs and preliminary evaluation of their TNF inhibitory effects
P Alexiou, A Papakyriakou, E Ntougkos, CP Papaneophytou, F Liepouri, ...
Archiv der Pharmazie 347 (11), 798-805, 2014
302014
Design and synthesis of N-(3, 5-difluoro-4-hydroxyphenyl) benzenesulfonamides as aldose reductase inhibitors
P Alexiou, I Nicolaou, M Stefek, A Kristl, VJ Demopoulos
Bioorganic & medicinal chemistry 16 (7), 3926-3932, 2008
262008
Compounds that combine aldose reductase inhibitory activity and ability to prevent the glycation (glucation and/or fructation) of proteins as putative pharmacotherapeutic agents
VJ Demopoulos, N Zaher, C Zika, C Anagnostou, E Mamadou, P Alexiou, ...
Drug Design Reviews-Online (Discontinued) 2 (4), 293-304, 2005
232005
Medicinal plants used for the treatment of diabetes and its long-term complications
P Alexiou, VJ Demopoulos
Plants in Traditional and Modern Medicine: Chemistry and Activity 69, 175, 2010
222010
Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit morphine's rewarding effect in rats
V Katsidoni, P Alexiou, M Fotiadou, M Pelecanou, M Sagnou, G Panagis
Psychopharmacology 231, 4467-4478, 2014
202014
Synthesis and biological evaluation of potential small molecule inhibitors of tumor necrosis factor
C Papaneophytou, P Alexiou, A Papakyriakou, E Ntougkos, K Tsiliouka, ...
MedChemComm 6 (6), 1196-1209, 2015
132015
Isatin thiosemicarbazones promote honeycomb structure formation in spin-coated polymer films: concentration effect and release studies
VG Fernández-Luna, D Mallinson, P Alexiou, I Khadra, AB Mullen, ...
RSC advances 7 (21), 12945-12952, 2017
82017
Discovery of small-molecule inhibitors of receptor activator of nuclear factor-κb ligand with a superior therapeutic index
V Rinotas, A Papakyriakou, F Violitzi, C Papaneophytou, MD Ouzouni, ...
Journal of medicinal chemistry 63 (20), 12043-12059, 2020
72020
Isatin thiosemicarbazone-blended polymer films for biomedical applications: surface morphology, characterisation and preliminary biological assessment
D Mallinson, P Alexiou, AB Mullen, M Pelecanou, M Sagnou, DA Lamprou
RSC advances 6 (30), 24939-24945, 2016
62016
A new neural network ensemble heuristic for a predictor of the aldose reductase inhibitory activity
R Parra-Hernandez, EM Laxdal, NJ Dimopoulos, P Alexiou
Proceedings of the Fifth IEEE International Symposium on Signal Processing …, 2005
62005
Aqueous Solubility Enhancement for Bioassays of Insoluble Inhibitors and QSPR Analysis: A TNF-α Study
A Mettou, C Papaneophytou, G Melagraki, A Maranti, F Liepouri, ...
SLAS DISCOVERY: Advancing Life Sciences R&D 23 (1), 84-93, 2018
42018
Antiradical efficiency and aldose reductase inhibitory capacity of Cornelian cherry (Cornus mas L.) fruits' extracts
P Tsatalas, P Alexiou, V Demopoulos, E Kokkalou
Planta Medica 74 (09), PH28, 2008
12008
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