| Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis ME Ward, R Chen, HY Huang, C Ludwig, M Telpoukhovskaia, A Taubes, ... Science translational medicine 9 (385), eaah5642, 2017 | 173 | 2017 |
| The aged rhesus macaque manifests Braak stage III/IV Alzheimer's-like pathology CD Paspalas, BC Carlyle, S Leslie, TM Preuss, JL Crimins, AJ Huttner, ... Alzheimer's & Dementia 14 (5), 680-691, 2018 | 93 | 2018 |
| Age‐related calcium dysregulation linked with tau pathology and impaired cognition in non‐human primates D Datta, SN Leslie, M Wang, YM Morozov, S Yang, SA Mentone, C Zeiss, ... Alzheimer's & Dementia 17 (6), 920-932, 2021 | 62* | 2021 |
| Alzheimer’s-like pathology in aging rhesus macaques: Unique opportunity to study the etiology and treatment of Alzheimer’s disease AFT Arnsten, D Datta, S Leslie, ST Yang, M Wang, AC Nairn Proceedings of the National Academy of Sciences 116 (52), 26230-26238, 2019 | 50 | 2019 |
| Classical complement cascade initiating C1q protein within neurons in the aged rhesus macaque dorsolateral prefrontal cortex D Datta, SN Leslie, YM Morozov, A Duque, P Rakic, CH van Dyck, ... Journal of Neuroinflammation 17, 1-15, 2020 | 46 | 2020 |
| cAMP regulation of protein phosphatases PP1 and PP2A in brain SN Leslie, AC Nairn Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1866 (1), 64-73, 2019 | 46 | 2019 |
| Glutamate carboxypeptidase II in aging rat prefrontal cortex impairs working memory performance D Datta, SN Leslie, E Woo, N Amancharla, A Elmansy, M Lepe, AP Mecca, ... Frontiers in Aging Neuroscience 13, 760270, 2021 | 13 | 2021 |
| Phosphodiesterase PDE4D is decreased in frontal cortex of aged rats and positively correlated with working memory performance and inversely correlated with PKA phosphorylation … SN Leslie, D Datta, KR Christensen, CH Van Dyck, AFT Arnsten, AC Nairn Frontiers in Aging Neuroscience 12, 576723, 2020 | 11 | 2020 |
| UBQLN2 restrains the domesticated retrotransposon PEG10 to maintain neuronal health in ALS HH Black, JL Hanson, JE Roberts, SN Leslie, W Campodonico, ... Elife 12, e79452, 2023 | 8 | 2023 |
| Simple, single-shot phosphoproteomic analysis of heat-stable tau identifies age-related changes in pS235-and pS396-tau levels in non-human primates SN Leslie, J Kanyo, D Datta, RS Wilson, C Zeiss, A Duque, TKT Lam, ... Frontiers in Aging Neuroscience 13, 767322, 2021 | 4 | 2021 |
| Mass spectrometry in cerebrospinal fluid uncovers association of glycolysis biomarkers with Alzheimer’s disease in a large clinical sample MB de Geus, SN Leslie, TK Lam, W Wang, F Roux-Dalvai, A Droit, ... Scientific Reports 13 (1), 22406, 2023 | 2 | 2023 |
| Mass spectrometry on cerebrospinal fluid uncovers association of novel glycolysis biomarkers with Alzheimer’s disease in a complex clinical cohort MB de Geus, SN Leslie, W Wang, TK Lam, M Broekman, S Neefjes, ... Alzheimer's & Dementia 19, e078466, 2023 | | 2023 |
| Enhancing Classification of liquid chromatography mass spectrometry data with Batch Effect Removal Neural Networks (BERNN) A Droit, S Pelletier, M Leclerq, F Roux-Dalvai, M de Geus, S Leslie, ... Research Square, 2023 | | 2023 |
| Methods For The Identification Of UBQLN2-Mediated Amyotrophic Lateral Sclerosis (ALS) A Whiteley, SN Leslie US Patent App. 17/822,992, 2023 | | 2023 |
| Applying Data‐Independent Acquisition Mass Spectrometry on Cerebrospinal Fluid Samples from a Neurology Clinic for Biomarker Discovery in Alzheimer’s Disease MB de Geus, SN Leslie, CE Ramirez, BA Trombetta, W Wang, T Lam, ... Alzheimer's & Dementia 18, e064314, 2022 | | 2022 |
| Molecular Mechanisms of Aging and Alzheimer’s Disease SN Leslie Yale University, 2021 | | 2021 |
| Biochemical characterization of age‐related calcium‐cAMP‐PKA signaling dysregulation and its effect on tau pathology in rhesus monkey cortex: Molecular and cell biology/calcium … SN Leslie, D Datta, M Wang, CH van Dyck, AFT Arnsten, AC Nairn Alzheimer's & Dementia 16, e042017, 2020 | | 2020 |
| Development of a robust and stable mass based spectrometry method for analysis of Alzheimer’s disease biomarkers in human cerebrospinal fluid: Biomarkers (non‐neuroimaging … SN Leslie, R Wilson, BA Trombetta, P Kivisäkk, SE Arnold, AC Nairn, ... Alzheimer's & Dementia 16, e042035, 2020 | | 2020 |
| P1‐269: DEVELOPMENT AND TECHNICAL VALIDATION OF A DATA‐INDEPENDENT ACQUISITION METHODOLOGY FOR ANALYSIS OF HUMAN ALZHEIMER'S DISEASE CEREBROSPINAL FLUID S Leslie, R Wilson, P Kivisäkk, SE Kandigian, BA Trombetta, AC Nairn, ... Alzheimer's & Dementia 15, P342-P342, 2019 | | 2019 |
| P1‐274: A TARGETED MASS‐SPECTROMETRY METHOD FOR QUANTIFICATION OF CEREBROSPINAL FLUID BIOMARKERS OF ALZHEIMER'S DISEASE BC Carlyle, S Leslie, BA Trombetta, CK Nobuhara, CH van Dyck, ... Alzheimer's & Dementia 14 (7S_Part_7), P387-P387, 2018 | | 2018 |
