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Brennan Dirk
Brennan Dirk
IMV Inc.
Verified email at imv-inc.com
Title
Cited by
Cited by
Year
HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling
BS Dirk, EN Pawlak, AL Johnson, LR Van Nynatten, RA Jacob, B Heit, ...
Scientific reports 6 (1), 37021, 2016
752016
MIiSR: molecular interactions in super-resolution imaging enables the analysis of protein interactions, dynamics and formation of multi-protein structures
FA Caetano, BS Dirk, JHK Tam, PC Cavanagh, M Goiko, SSG Ferguson, ...
PLoS computational biology 11 (12), e1004634, 2015
432015
The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4+ T cells
EN Pawlak, BS Dirk, RA Jacob, AL Johnson, JD Dikeakos
Retrovirology 15, 1-22, 2018
322018
The interaction between HIV-1 Nef and adaptor protein-2 reduces Nef-mediated CD4+ T cell apoptosis
RA Jacob, AL Johnson, EN Pawlak, BS Dirk, LR Van Nynatten, ...
Virology 509, 1-10, 2017
222017
Antagonistic coevolution of MER tyrosine kinase expression and function
AL Evans, JWD Blackburn, K Taruc, A Kipp, BS Dirk, NR Hunt, SD Barr, ...
Molecular biology and evolution 34 (7), 1613-1628, 2017
192017
Functional and structural mimicry of cellular protein kinase A anchoring proteins by a viral oncoprotein
CR King, MJ Cohen, GJ Fonseca, BS Dirk, JD Dikeakos, JS Mymryk
PLoS pathogens 12 (5), e1005621, 2016
192016
Viral bimolecular fluorescence complementation: a novel tool to study intracellular vesicular trafficking pathways
BS Dirk, RA Jacob, AL Johnson, EN Pawlak, PC Cavanagh, ...
PLoS One 10 (4), e0125619, 2015
192015
Upregulation of BST-2 by type I interferons reduces the capacity of Vpu to protect HIV-1-infected cells from NK cell responses
J Prévost, S Pickering, MJ Mumby, H Medjahed, G Gendron-Lepage, ...
MBio 10 (3), 10.1128/mbio. 01113-19, 2019
132019
A highly conserved residue in HIV-1 Nef alpha helix 2 modulates protein expression
AL Johnson, BS Dirk, M Coutu, SMM Haeryfar, EJ Arts, A Finzi, ...
Msphere 1 (6), 10.1128/msphere. 00288-16, 2016
122016
Where in the cell are you? Probing HIV-1 host interactions through advanced imaging techniques
BS Dirk, LR Van Nynatten, JD Dikeakos
Viruses 8 (10), 288, 2016
122016
Visualizing interactions between HIV-1 Nef and host cellular proteins using ground-state depletion microscopy
BS Dirk, B Heit, JD Dikeakos
AIDS research and human retroviruses 31 (7), 671, 2015
112015
DPX-Survivac, a novel T-cell immunotherapy, to induce robust T-cell responses in advanced ovarian cancer.
O Dorigo, S Fiset, LD MacDonald, Y Bramhecha, O Hrytsenko, B Dirk, ...
Journal of Clinical Oncology 38 (5_suppl), 6-6, 2020
102020
PACS-1 and adaptor protein-1 mediate ACTH trafficking to the regulated secretory pathway
BS Dirk, C End, EN Pawlak, LR Van Nynatten, RA Jacob, B Heit, ...
Biochemical and biophysical research communications 507 (1-4), 519-525, 2018
42018
Pathogenic infection of Rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV-1 infections
M Asmal, S Lane, M Tian, G Nickel, C Venner, B Dirk, J Dikeakos, ...
Virology 499, 298-312, 2016
42016
1334 AVA-ADR-001 supresses tumor growth and induces anti-tumor immunity by selectively inhibiting ADAR1 p150
AB Papaiah, A Goswami, S Goyal, K Singh, P Khurana, A Kulkarni
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
12022
Identification of Novel Subcellular Localization and Trafficking of HIV-1 Nef Variants from Reference Strains G (F1. 93. HH8793) and H (BE. 93. VI997)
LR Van Nynatten, AL Johnson, BS Dirk, EN Pawlak, RA Jacob, ...
Viruses 10 (9), 493, 2018
12018
Acetylenic tricyclic bis-(cyano enone) interacts with Cys 374 of actin, a residue necessary for stress fiber formation and cell migration
E Chan, BS Dirk, T Honda, PB Stathopulos, JD Dikeakos, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1871 (2), 119629, 2024
2024
NK cells are involved in promoting anti-tumor responses to DPX-peptide immunotherapy
M Bydoun, D Medina-Luna, B Dirk, J Graff, O Hrytsenko, A Makrigiannis
Cancer Research 82 (12_Supplement), 623-623, 2022
2022
Proteomic analysis of plasma exosomes as biomarkers of response to MVP-S based immunotherapy
P Smith, E Teh, K Chisholm, S Penny, D Pinto, K Patterson, B Dirk, ...
The Journal of Immunology 208 (1_Supplement), 66.09-66.09, 2022
2022
Survivin peptides formulated in the DPX delivery platform rather than standard emulsions, elicit a robust, sustained T cell response to survivin in advanced and recurrent …
Y Bramhecha, O Dorigo, V Kaliaperumal, H Torrey, W Ebrahimizadeh, ...
MOLECULAR CANCER THERAPEUTICS 20 (12), 2021
2021
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