| Characterization of heme as activator of Toll-like receptor 4 RT Figueiredo, PL Fernandez, DS Mourao-Sa, BN Porto, FF Dutra, ... Journal of Biological Chemistry 282 (28), 20221-20229, 2007 | 611 | 2007 |
| Microglia receptors and their implications in the response to amyloid β for Alzheimer’s disease pathogenesis D Doens, PL Fernández Journal of neuroinflammation 11, 1-14, 2014 | 361 | 2014 |
| Hemolysis-induced lethality involves inflammasome activation by heme FF Dutra, LS Alves, D Rodrigues, PL Fernandez, RB De Oliveira, ... Proceedings of the National Academy of Sciences 111 (39), E4110-E4118, 2014 | 335 | 2014 |
| Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production GB Fortes, LS Alves, R De Oliveira, FF Dutra, D Rodrigues, PL Fernandez, ... Blood, The Journal of the American Society of Hematology 119 (10), 2368-2375, 2012 | 268 | 2012 |
| Heme induces neutrophil migration and reactive oxygen species generation through signaling pathways characteristic of chemotactic receptors BN Porto, LS Alves, PL Fernández, TP Dutra, RT Figueiredo, ... Journal of Biological Chemistry 282 (33), 24430-24436, 2007 | 183 | 2007 |
| An α-glucan of Pseudallescheria boydii is involved in fungal phagocytosis and toll-like receptor activation VCB Bittencourt, RT Figueiredo, RB da Silva, DS Mourão-Sá, ... Journal of biological chemistry 281 (32), 22614-22623, 2006 | 151 | 2006 |
| Heme amplifies the innate immune response to microbial molecules through spleen tyrosine kinase (Syk)-dependent reactive oxygen species generation PL Fernandez, FF Dutra, L Alves, RT Figueiredo, D Mourao-Sa, GB Fortes, ... Journal of Biological Chemistry 285 (43), 32844-32851, 2010 | 91 | 2010 |
| Marine diterpenoids as potential anti-inflammatory agents Y González, D Torres-Mendoza, GE Jones, PL Fernandez Mediators of Inflammation 2015, 2015 | 69 | 2015 |
| Potential immunotargets for Alzheimer's disease treatment strategies PL Fernández, GB Britton, KS Rao Journal of Alzheimer's Disease 33 (2), 297-312, 2013 | 47 | 2013 |
| Assessment of novel curcumin derivatives as potent inhibitors of inflammation and amyloid-β aggregation in Alzheimer’s disease J Lakey-Beitia, Y González, D Doens, DE Stephens, R Santamaría, ... Journal of Alzheimer's Disease 60 (s1), S59-S68, 2017 | 44 | 2017 |
| Anti-amyloid aggregation activity of novel carotenoids: implications for Alzheimer’s drug discovery J Lakey-Beitia, D Doens, D Jagadeesh Kumar, E Murillo, PL Fernandez, ... Clinical Interventions in Aging, 815-822, 2017 | 43 | 2017 |
| Identification of inhibitors of CD36-amyloid beta binding as potential agents for Alzheimer’s disease D Doens, PA Valiente, AM Mfuh, A XT Vo, A Tristan, L Carreño, M Quijada, ... ACS chemical neuroscience 8 (6), 1232-1241, 2017 | 42 | 2017 |
| TLR4 recognizes Pseudallescheria boydii conidia and purified rhamnomannans RT Figueiredo, PL Fernandez, FF Dutra, Y González, LC Lopes, ... Journal of biological chemistry 285 (52), 40714-40723, 2010 | 42 | 2010 |
| Mitochondrial reactive oxygen species participate in signaling triggered by heme in macrophages and upon hemolysis EB Prestes, LS Alves, DAS Rodrigues, FF Dutra, PL Fernandez, CN Paiva, ... The Journal of Immunology 205 (10), 2795-2805, 2020 | 23 | 2020 |
| Flavonoids from Boldoa purpurascens inhibit proinflammatory cytokines (TNF‐α and IL‐6) and the expression of COX‐2 DM González Mosquera, Y Hernández Ortega, PL Fernández, ... Phytotherapy Research 32 (9), 1750-1754, 2018 | 22 | 2018 |
| A Pseudopterane Diterpene Isolated From the Octocoral Pseudopterogorgia acerosa Inhibits the Inflammatory Response Mediated by TLR-Ligands and TNF-Alpha … Y González, D Doens, R Santamaría, M Ramos, CM Restrepo, ... PLoS One 8 (12), e84107, 2013 | 22 | 2013 |
| Performance of a point of care test for detecting IgM and IgG antibodies against SARS-CoV-2 and seroprevalence in blood donors and health care workers in Panama A Villarreal, G Rangel, X Zhang, D Wong, G Britton, PL Fernandez, ... Frontiers in Medicine 8, 616106, 2021 | 19 | 2021 |
| Both B‐1a and B‐1b cells exposed to Mycobacterium tuberculosis lipids differentiate into IgM antibody‐secreting cells C Ordoñez, HP Savage, M Tarajia, R Rivera, C Weeks‐Galindo, ... Immunology 154 (4), 613-623, 2018 | 17 | 2018 |
| seco-Briarellinone and Briarellin S, Two New Eunicellin-Based Diterpenoids from the Panamanian Octocoral Briareum asbestinum JF Gómez-Reyes, A Salazar, HM Guzmán, Y González, PL Fernández, ... Marine Drugs 10 (11), 2608-2617, 2012 | 17 | 2012 |
| Insights into the structural patterns of the antileishmanial activity of bi-and tricyclic N-heterocycles L Herrera, DE Stephens, A D'Avila, KG George, H Arman, Y Zhang, ... Organic & biomolecular chemistry 14 (29), 7053-7060, 2016 | 15 | 2016 |
