Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial RECOVERY Collaborative Group Lancet (London, England) 397 (10285), 1637, 2021 | 1988* | 2021 |
Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind … HGM Heijerman, EF McKone, DG Downey, E Van Braeckel, SM Rowe, ... The Lancet 394 (10212), 1940-1948, 2019 | 1013 | 2019 |
Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial RECOVERY Collaborative Group, PW Horby, M Mafham, L Peto, ... Medrxiv, 2021.06. 15.21258542, 2021 | 495* | 2021 |
Neutrophils in cystic fibrosis DG Downey, SC Bell, JS Elborn Thorax 64 (1), 81-88, 2009 | 270 | 2009 |
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis O Abani, A Abbas, F Abbas, J Abbas, K Abbas, M Abbas, S Abbasi, ... The Lancet 400 (10349), 359-368, 2022 | 221 | 2022 |
Safety and Efficacy of Recombinant Alpha1‐Antitrypsin Therapy in Cystic Fibrosis SL Martin, D Downey, D Bilton, MT Keogan, J Edgar, JS Elborn Pediatric pulmonology 41 (2), 177-183, 2006 | 117 | 2006 |
Efficacy and safety of elexacaftor plus tezacaftor plus ivacaftor versus tezacaftor plus ivacaftor in people with cystic fibrosis homozygous for F508del-CFTR: a 24-week … S Sutharsan, EF McKone, DG Downey, J Duckers, G MacGregor, E Tullis, ... The Lancet Respiratory Medicine 10 (3), 267-277, 2022 | 80 | 2022 |
The relationship of clinical and inflammatory markers to outcome in stable patients with cystic fibrosis DG Downey, SL Martin, M Dempster, JE Moore, MT Keogan, B Starcher, ... Pediatric pulmonology 42 (3), 216-220, 2007 | 77 | 2007 |
The effect of treatment of cystic fibrosis pulmonary exacerbations on airways and systemic inflammation DG Downey, S Brockbank, SL Martin, M Ennis, JS Elborn Pediatric pulmonology 42 (8), 729-735, 2007 | 76 | 2007 |
Nitric oxide, iNOS, and inflammation in cystic fibrosis D Downey, JS Elborn The Journal of Pathology: A Journal of the Pathological Society of Great …, 2000 | 53 | 2000 |
Failure to conceive in women with CF is associated with pancreatic insufficiency and advancing age M Shteinberg, AB Lulu, DG Downey, Z Blumenfeld, C Rousset-Jablonski, ... Journal of Cystic Fibrosis 18 (4), 525-529, 2019 | 50 | 2019 |
Current pregnancy outcomes in women with cystic fibrosis C Burden, R Ion, Y Chung, A Henry, DG Downey, J Trinder European Journal of Obstetrics & Gynecology and Reproductive Biology 164 (2 …, 2012 | 49 | 2012 |
Airway inflammation and host responses in the era of CFTR modulators K Keown, R Brown, DF Doherty, C Houston, MC McKelvey, S Creane, ... International journal of molecular sciences 21 (17), 6379, 2020 | 45 | 2020 |
Effect of cystic fibrosis exacerbations on neutrophil function S Brockbank, D Downey, JS Elborn, M Ennis International immunopharmacology 5 (3), 601-608, 2005 | 45 | 2005 |
VX17-445-103 Trial Group Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del … HGM Heijerman, EF McKone, DG Downey, E Van Braeckel, SM Rowe, ... Lancet 394 (10212), 1940-1948, 2019 | 43 | 2019 |
Lung clearance index in adults and children with cystic fibrosis K O’Neill, MM Tunney, E Johnston, S Rowan, DG Downey, J Rendall, ... Chest 150 (6), 1323-1332, 2016 | 43 | 2016 |
Long-term safety and efficacy of tezacaftor–ivacaftor in individuals with cystic fibrosis aged 12 years or older who are homozygous or heterozygous for Phe508del CFTR (EXTEND … PA Flume, RF Biner, DG Downey, C Brown, M Jain, R Fischer, ... The Lancet Respiratory Medicine 9 (7), 733-746, 2021 | 42 | 2021 |
Heat and fluid flow in welds J Goldak, MJ Bibby, D Downey, M Gu Advanced Joining Technologies: Proceedings of the International Institute of …, 1990 | 40 | 1990 |
Future therapies for cystic fibrosis L Allen, L Allen, SB Carr, G Davies, D Downey, M Egan, JT Forton, R Gray, ... Nature communications 14 (1), 693, 2023 | 38 | 2023 |
Community analysis and co-occurrence patterns in airway microbial communities during health and disease GG Einarsson, J Zhao, JJ LiPuma, DG Downey, MM Tunney, JS Elborn ERJ open research 5 (3), 2019 | 37 | 2019 |