| Binding affinity via docking: fact and fiction T Pantsar, A Poso Molecules 23 (8), 1899, 2018 | 461 | 2018 |
| A MYC–aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer D Dauch, R Rudalska, G Cossa, JC Nault, TW Kang, T Wuestefeld, ... Nature medicine 22 (7), 744-753, 2016 | 272 | 2016 |
| Characterization of the sulfhydryl-sensitive site in the enzyme responsible for hydrolysis of 2-arachidonoyl-glycerol in rat cerebellar membranes SM Saario, OMH Salo, T Nevalainen, A Poso, JT Laitinen, T Järvinen, ... Chemistry & biology 12 (6), 649-656, 2005 | 194 | 2005 |
| DeepCDA: deep cross-domain compound–protein affinity prediction through LSTM and convolutional neural networks K Abbasi, P Razzaghi, A Poso, M Amanlou, JB Ghasemi, ... Bioinformatics 36 (17), 4633-4642, 2020 | 145 | 2020 |
| An in silico approach to discovering novel inhibitors of human sirtuin type 2 AJ Tervo, S Kyrylenko, P Niskanen, A Salminen, J Leppänen, TH Nyrönen, ... Journal of medicinal chemistry 47 (25), 6292-6298, 2004 | 129 | 2004 |
| Prediction of human population responses to toxic compounds by a collaborative competition. Nature Biotechnology 33, 933-940, 2015 | 121 | 2015 |
| Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase N Aaltonen, JR Savinainen, CR Ribas, J Rönkkö, A Kuusisto, J Korhonen, ... Chemistry & biology 20 (3), 379-390, 2013 | 112 | 2013 |
| Development of a 3D model for the human cannabinoid CB1 receptor OMH Salo, M Lahtela-Kakkonen, J Gynther, T Järvinen, A Poso Journal of medicinal chemistry 47 (12), 3048-3057, 2004 | 104 | 2004 |
| Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors T Huhtiniemi, T Suuronen, VM Rinne, C Wittekindt, M Lahtela-Kakkonen, ... Journal of medicinal chemistry 51 (15), 4377-4380, 2008 | 103 | 2008 |
| Integrative and personalized QSAR analysis in cancer by kernelized Bayesian matrix factorization M Ammad-Ud-Din, E Georgii, M Gonen, T Laitinen, O Kallioniemi, ... Journal of chemical information and modeling 54 (8), 2347-2359, 2014 | 102 | 2014 |
| Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells D Rotili, D Tarantino, A Nebbioso, C Paolini, C Huidobro, E Lara, P Mellini, ... Journal of medicinal chemistry 55 (24), 10937-10947, 2012 | 95 | 2012 |
| Targeting the cannabinoid CB2 receptor: modelling and structural determinants of CB2 selective ligands A Poso, JW Huffman British journal of pharmacology 153 (2), 335-346, 2008 | 92 | 2008 |
| Predictive three-dimensional quantitative structure− activity relationship of cytochrome P450 1A2 inhibitors LE Korhonen, M Rahnasto, NJ Mähönen, C Wittekindt, A Poso, ... Journal of medicinal chemistry 48 (11), 3808-3815, 2005 | 91 | 2005 |
| Targeting the cannabinoid CB2 receptor: mutations, modeling and development of CB2 selective ligands KH Raitio, OMH Salo, T Nevalainen, A Poso, T Jarvinen Current medicinal chemistry 12 (10), 1217-1237, 2005 | 87 | 2005 |
| A rhodopsin-based model for melatonin recognition at its G protein-coupled receptor C Navajas, T Kokkola, A Poso, N Honka, J Gynther, JT Laitinen European journal of pharmacology 304 (1-3), 173-183, 1996 | 84 | 1996 |
| The effect of ligand-based tautomer and protomer prediction on structure-based virtual screening T Kalliokoski, HS Salo, M Lahtela-Kakkonen, A Poso Journal of Chemical Information and Modeling 49 (12), 2742-2748, 2009 | 80 | 2009 |
| Virtual screening of novel CB2 ligands using a comparative model of the human cannabinoid CB2 receptor OMH Salo, KH Raitio, JR Savinainen, T Nevalainen, M Lahtela-Kakkonen, ... Journal of medicinal chemistry 48 (23), 7166-7171, 2005 | 76 | 2005 |
| Deep learning in drug target interaction prediction: current and future perspectives K Abbasi, P Razzaghi, A Poso, S Ghanbari-Ara, A Masoudi-Nejad Current Medicinal Chemistry 28 (11), 2100-2113, 2021 | 75 | 2021 |
| Fatty acid amide hydrolase inhibitors from virtual screening of the endocannabinoid system SM Saario, A Poso, RO Juvonen, T Järvinen, OMH Salo-Ahen Journal of medicinal chemistry 49 (15), 4650-4656, 2006 | 75 | 2006 |
| Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling T Pantsar, S Rissanen, D Dauch, T Laitinen, I Vattulainen, A Poso PLoS computational biology 14 (9), e1006458, 2018 | 74 | 2018 |
Agnieszka A. KaczorMedical University of LublinVerified email at umlub.pl
