The landscape of genomic alterations across childhood cancers SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ... Nature 555 (7696), 321-327, 2018 | 1282 | 2018 |
MINCR is a MYC-induced lncRNA able to modulate MYC’s transcriptional network in Burkitt lymphoma cells G Doose, A Haake, SH Bernhart, C López, S Duggimpudi, F Wojciech, ... Proceedings of the National Academy of Sciences 112 (38), E5261-E5270, 2015 | 106 | 2015 |
MYC/MIZ1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation A Shostak, B Ruppert, N Ha, P Bruns, UH Toprak, R Eils, M Schlesner, ... Nature communications 7 (1), 11807, 2016 | 102 | 2016 |
Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity M Keller, L Hopp, X Liu, T Wohland, K Rohde, R Cancello, M Klös, ... Molecular metabolism 6 (1), 86-100, 2017 | 97 | 2017 |
RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas M Kunz, H Löffler-Wirth, M Dannemann, E Willscher, G Doose, J Kelso, ... Oncogene 37 (47), 6136-6151, 2018 | 92 | 2018 |
Mapping heterogeneity in patient-derived melanoma cultures by single-cell RNA-seq T Gerber, E Willscher, H Loeffler-Wirth, L Hopp, D Schadendorf, M Schartl, ... Oncotarget 8 (1), 846, 2017 | 77 | 2017 |
Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome H Binder, L Hopp, MR Schweiger, S Hoffmann, F Jühling, M Kerick, ... The Journal of pathology 243 (2), 242-254, 2017 | 65 | 2017 |
DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development H Binder, E Willscher, H Loeffler-Wirth, L Hopp, DTW Jones, SM Pfister, ... Acta neuropathologica communications 7, 1-18, 2019 | 55 | 2019 |
A modular transcriptome map of mature B cell lymphomas H Loeffler-Wirth, M Kreuz, L Hopp, A Arakelyan, A Haake, SB Cogliatti, ... Genome medicine 11, 1-20, 2019 | 45 | 2019 |
Portraying the expression landscapes of cancer subtypes: A case study of glioblastoma multiforme and prostate cancer L Hopp, H Wirth, M Fasold, H Binder Systems Biomedicine 1 (2), 99-121, 2013 | 42 | 2013 |
Portraying the expression landscapes of cancer subtypes: a glioblastoma multiforme and prostate cancer case study L Hopp, H Wirth, M Fasold, H Binder | 42* | |
Epigenetic heterogeneity of B-cell lymphoma: DNA methylation, gene expression and chromatin states L Hopp, H Löffler-Wirth, H Binder Genes 6 (3), 812-840, 2015 | 37 | 2015 |
Telomere length maintenance and its transcriptional regulation in lynch syndrome and sporadic colorectal carcinoma L Nersisyan, L Hopp, H Loeffler-Wirth, J Galle, M Loeffler, A Arakelyan, ... Frontiers in Oncology 9, 1172, 2019 | 36 | 2019 |
Footprints of sepsis framed within community acquired pneumonia in the blood transcriptome L Hopp, H Loeffler-Wirth, L Nersisyan, A Arakelyan, H Binder Frontiers in immunology 9, 1620, 2018 | 35 | 2018 |
DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: the CENTRAL trial M Keller, A Yaskolka Meir, SH Bernhart, Y Gepner, I Shelef, ... Genome medicine 12, 1-18, 2020 | 33 | 2020 |
A global genome segmentation method for exploration of epigenetic patterns L Steiner, L Hopp, H Wirth, J Galle, H Binder, SJ Prohaska, T Rohlf Public Library of Science 7 (10), e46811, 2012 | 30 | 2012 |
The human blood transcriptome in a large population cohort and its relation to aging and health M Schmidt, L Hopp, A Arakelyan, H Kirsten, C Engel, K Wirkner, K Krohn, ... Frontiers in big Data 3, 548873, 2020 | 28 | 2020 |
Combined SOM-portrayal of gene expression and DNA methylation landscapes disentangles modes of epigenetic regulation in glioblastoma L Hopp, H Löffler-Wirth, J Galle, H Binder Epigenomics 10 (6), 745-764, 2018 | 24 | 2018 |
IRS1 DNA promoter methylation and expression in human adipose tissue are related to fat distribution and metabolic traits K Rohde, M Klös, L Hopp, X Liu, M Keller, M Stumvoll, A Dietrich, ... Scientific reports 7 (1), 12369, 2017 | 23 | 2017 |
Bistable epigenetic states explain age-dependent decline in mesenchymal stem cell heterogeneity Z Hamidouche, K Rother, J Przybilla, A Krinner, D Clay, L Hopp, C Fabian, ... Stem Cells 35 (3), 694-704, 2017 | 22 | 2017 |