| Antitumor benzothiazoles. 26. 2-(3, 4-Dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective … CG Mortimer, G Wells, JP Crochard, EL Stone, TD Bradshaw, ... Journal of Medicinal Chemistry 49 (1), 179-185, 2006 | 562 | 2006 |
| Antitumor Benzothiazoles. 3. Synthesis of 2-(4-Aminophenyl)benzothiazoles and Evaluation of Their Activities against Breast Cancer Cell Lines in Vitro and in Vivo DF Shi, TD Bradshaw, S Wrigley, CJ McCall, P Lelieveld, I Fichtner, ... Journal of medicinal chemistry 39 (17), 3375-3384, 1996 | 513 | 1996 |
| Antitumor benzothiazoles. 14. Synthesis and in vitro biological properties of fluorinated 2-(4-aminophenyl) benzothiazoles I Hutchinson, MS Chua, HL Browne, V Trapani, TD Bradshaw, ... Journal of medicinal chemistry 44 (9), 1446-1455, 2001 | 450 | 2001 |
| Insights into low molecular mass organic gelators: a focus on drug delivery and tissue engineering applications KJ Skilling, F Citossi, TD Bradshaw, M Ashford, B Kellam, M Marlow Soft matter 10 (2), 237-256, 2014 | 395 | 2014 |
| Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3, 4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX … S Aiello, G Wells, EL Stone, H Kadri, R Bazzi, DR Bell, MFG Stevens, ... Journal of Medicinal Chemistry 51 (16), 5135-5139, 2008 | 391 | 2008 |
| Antitumor Benzothiazoles. 8. Synthesis, Metabolic Formation, and Biological Properties of the C- and N-Oxidation Products of Antitumor 2-(4-Aminophenyl … E Kashiyama, I Hutchinson, MS Chua, SF Stinson, LR Phillips, G Kaur, ... Journal of medicinal chemistry 42 (20), 4172-4184, 1999 | 341 | 1999 |
| The development of the antitumour benzothiazole prodrug, Phortress, as a clinical candidate TD Bradshaw, AD Westwell Current medicinal chemistry 11 (8), 1009-1021, 2004 | 338 | 2004 |
| 2-(4-Aminophenyl) benzothiazoles: novel agents with selective profiles of in vitro anti-tumour activity TD Bradshaw, S Wrigley, DF Shi, RJ Schultz, KD Paull, MFG Stevens British journal of cancer 77 (5), 745-752, 1998 | 275 | 1998 |
| Antitumour benzothiazoles. Part 20: 3′-cyano and 3′-alkynyl-substituted 2-(4′-aminophenyl) benzothiazoles as new potent and selective analogues I Hutchinson, TD Bradshaw, CS Matthews, MFG Stevens, AD Westwell Bioorganic & medicinal chemistry letters 13 (3), 471-474, 2003 | 174 | 2003 |
| Cinnamaldehydes inhibit thioredoxin reductase and induce Nrf2: potential candidates for cancer therapy and chemoprevention EH Chew, AA Nagle, Y Zhang, S Scarmagnani, P Palaniappan, ... Free Radical Biology and Medicine 48 (1), 98-111, 2010 | 171 | 2010 |
| Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death A Athanasiou, AB Clarke, AE Turner, NM Kumaran, S Vakilpour, PA Smith, ... Biochemical and biophysical research communications 364 (1), 131-137, 2007 | 169 | 2007 |
| Antitumor benzothiazoles. 7. Synthesis of 2-(4-acylaminophenyl) benzothiazoles and investigations into the role of acetylation in the antitumor activities of the parent amines MS Chua, DF Shi, S Wrigley, TD Bradshaw, I Hutchinson, PN Shaw, ... Journal of medicinal chemistry 42 (3), 381-392, 1999 | 162 | 1999 |
| Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl) benzothiazoles TD Bradshaw, MC Bibby, JA Double, I Fichtner, PA Cooper, MC Alley, ... Molecular Cancer Therapeutics 1 (4), 239-246, 2002 | 159 | 2002 |
| The discovery of the potent and selective antitumour agent 2-(4-amino-3-methylphenyl) benzothiazole (DF 203) and related compounds TD Bradshaw, MFG Stevens, AD Westwell Current medicinal chemistry 8 (2), 203-210, 2001 | 151 | 2001 |
| Role of CYP1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl) benzothiazole (DF 203, NSC 674495) in human breast cancer cells MS Chua, E Kashiyama, TD Bradshaw, SF Stinson, E Brantley, ... Cancer research 60 (18), 5196-5203, 2000 | 151 | 2000 |
| Antitumour 2-(4-aminophenyl) benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo CO Leong, M Gaskell, EA Martin, RT Heydon, PB Farmer, MC Bibby, ... British journal of cancer 88 (3), 470-477, 2003 | 150 | 2003 |
| Antitumour benzothiazoles. Part 10: the synthesis and antitumour activity of benzothiazole substituted quinol derivatives G Wells, TD Bradshaw, P Diana, A Seaton, DF Shi, AD Westwell, ... Bioorganic & medicinal chemistry letters 10 (5), 513-515, 2000 | 146 | 2000 |
| Antitumour properties of fluorinated benzothiazole-substituted hydroxycyclohexa-2, 5-dienones (‘quinols’) CJ Lion, CS Matthews, G Wells, TD Bradshaw, MFG Stevens, ... Bioorganic & medicinal chemistry letters 16 (19), 5005-5008, 2006 | 144 | 2006 |
| 4-Substituted 4-hydroxycyclohexa-2, 5-dien-1-ones with selective activities against colon and renal cancer cell lines G Wells, JM Berry, TD Bradshaw, AM Burger, A Seaton, B Wang, ... Journal of medicinal chemistry 46 (4), 532-541, 2003 | 140 | 2003 |
| Acquired resistance to temozolomide in glioma cell lines: molecular mechanisms and potential translational applications J Zhang, MFG Stevens, CA Laughton, S Madhusudan, TD Bradshaw Oncology 78 (2), 103-114, 2010 | 137 | 2010 |
