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sima zacharek
sima zacharek
Moderna
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Cited by
Year
Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus
Q Lu, M Kaplan, D Ray, D Ray, S Zacharek, D Gutsch, B Richardson
Arthritis & Rheumatism 46 (5), 1282-1291, 2002
3582002
Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors
M Yu, T Mazor, H Huang, HT Huang, KL Kathrein, AJ Woo, CR Chouinard, ...
Molecular cell 45 (3), 330-343, 2012
2542012
Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion
JS Dovey, SJ Zacharek, CF Kim, JA Lees
Proceedings Of The National Academy Of Sciences 105 (33), 11857-11862, 2008
2282008
Durable anticancer immunity from intratumoral administration of IL-23, IL-36γ, and OX40L mRNAs
SL Hewitt, A Bai, D Bailey, K Ichikawa, J Zielinski, R Karp, A Apte, ...
Science translational medicine 11 (477), eaat9143, 2019
1962019
WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1–CUL4–ROC1 ligase
J Hu, S Zacharek, YJ He, H Lee, S Shumway, RJ Duronio, Y Xiong
Genes & development 22 (7), 866-871, 2008
1692008
Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci
SJ Zacharek, CM Fillmore, AN Lau, DW Gludish, A Chou, JWK Ho, ...
Cell stem cell 9 (3), 272-281, 2011
1522011
The combined effect of FGFR inhibition and PD-1 blockade promotes tumor-intrinsic induction of antitumor immunity
S Palakurthi, M Kuraguchi, SJ Zacharek, E Zudaire, W Huang, DM Bonal, ...
Cancer immunology research 7 (9), 1457-1471, 2019
1172019
Bacteria targeted by human natural antibodies using α-Gal conjugated receptor-specific glycopolymers
J Li, S Zacharek, X Chen, J Wang, W Zhang, A Janczuk, PG Wang
Bioorganic & medicinal chemistry 7 (8), 1549-1558, 1999
981999
Enhanced inhibition of human anti-gal antibody binding to mammalian cells by synthetic α-gal epitope polymers
JQ Wang, X Chen, W Zhang, S Zacharek, Y Chen, PG Wang
Journal of the American Chemical Society 121 (36), 8174-8181, 1999
941999
Negative regulation of TSC1-TSC2 by mammalian D-type cyclins
SJ Zacharek, Y Xiong, SD Shumway
Cancer research 65 (24), 11354-11360, 2005
842005
Duality of p27Kip1 function in tumorigenesis
P Sicinski, S Zacharek, C Kim
Genes & development 21 (14), 1703-1706, 2007
692007
A phase I study of mRNA-2752, a lipid nanoparticle encapsulating mRNAs encoding human OX40L, IL-23, and IL-36γ, for intratumoral (iTu) injection alone and in combination with …
MR Patel, TM Bauer, A Jimeno, D Wang, P LoRusso, KT Do, SM Stemmer, ...
Journal of Clinical Oncology 38 (15_suppl), 3092-3092, 2020
542020
PLA2 promotes fusion between PMN-specific granules and complex liposomes
RA Blackwood, AT Transue, DM Harsh, RC Brower, SJ Zacharek, ...
Journal of Leucocyte Biology 59 (5), 663-670, 1996
341996
Abstract CT032: A phase 1/2, open-label, multicenter, dose escalation and efficacy study of mRNA-2416, a lipid nanoparticle encapsulated mRNA encoding human OX40L, for …
A Jimeno, S Gupta, R Sullivan, KT Do, WL Akerley, D Wang, D Teoh, ...
Cancer Research 80 (16_Supplement), CT032-CT032, 2020
292020
The combined effect of FGFR inhibition and PD-1 blockade promotes tumor-intrinsic induction of antitumor immunity. Cancer Immunol. Res. 2019; 7: 1457–1471. doi: 10.1158/2326-6066
S Palakurthi, M Kuraguchi, SJ Zacharek, E Zudaire, W Huang, DM Bonal, ...
CIR-18-0595.[Abstract][CrossRef][Google Scholar], 2019
202019
Spatial Mapping and Immunomodulatory Role of the OX40/OX40L Pathway in Human Non–Small Cell Lung Cancer
A Porciuncula, M Morgado, R Gupta, K Syrigos, R Meehan, SJ Zacharek, ...
Clinical Cancer Research 27 (22), 6174-6183, 2021
192021
539 Phase 1 study of mRNA-2752, a lipid nanoparticle encapsulating mRNAs encoding human OX40L/IL-23/IL-36γ, for intratumoral (ITu) injection+/-durvalumab in advanced solid …
M Patel, A Jimeno, D Wang, S Stemmer, T Bauer, R Sweis, R Geva, ...
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021
192021
Cell Type–dependent Requirement for PIP Box–regulated Cdt1 Destruction During S Phase
HO Lee, SJ Zacharek, Y Xiong, RJ Duronio
Molecular biology of the cell 21 (21), 3639-3653, 2010
192010
Stem cell biology in the lung and lung cancers: using pulmonary context and classic approaches
DM Raiser, SJ Zacharek, RR Roach, SJ Curtis, KW Sinkevicius, ...
Cold Spring Harbor Symposia on Quantitative Biology 73, 479-490, 2008
142008
Abstract CT210: A Phase I, open-label, multicenter, dose escalation study of mRNA-2752, a lipid nanoparticle encapsulating mRNAs encoding human OX40L, IL-23, and IL-36γ, for …
T Bauer, M Patel, A Jimeno, D Wang, J McDermott, S Zacharek, ...
Cancer Research 79 (13_Supplement), CT210-CT210, 2019
132019
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