James W. Dennis
James W. Dennis
Professor of Molecular Genetics, University of Toronto
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β1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis
JW Dennis, S Laferté, C Waghorne, ML Breitman, RS Kerbel
Science 236 (4801), 582-585, 1987
Negative regulation of T-cell activation and autoimmunity by Mgat5N-glycosylation
M Demetriou, M Granovsky, S Quaggin, JW Dennis
Nature 409 (6821), 733-739, 2001
Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation
KS Lau, EA Partridge, A Grigorian, CI Silvescu, VN Reinhold, ...
Cell 129 (1), 123-134, 2007
Glycoprotein glycosylation and cancer progression
JW Dennis, M Granovsky, CE Warren
Biochimica et Biophysica Acta (BBA)-General Subjects 1473 (1), 21-34, 1999
Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis
EA Partridge, C Le Roy, GM Di Guglielmo, J Pawling, P Cheung, ...
Science 306 (5693), 120-124, 2004
Suppression of tumor growth and metastasis in Mgat5-deficient mice
M Granovsky, J Fata, J Pawling, WJ Muller, R Khokha, JW Dennis
Nature medicine 6 (3), 306-312, 2000
Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study
MR Loutfy, LM Blatt, KA Siminovitch, S Ward, B Wolff, H Lho, DH Pham, ...
Jama 290 (24), 3222-3228, 2003
Protein glycosylation in development and disease
JW Dennis, M Granovsky, CE Warren
Bioessays 21 (5), 412-421, 1999
Inhibitors of carbohydrate processing: A new class of anticancer agents.
PE Goss, MA Baker, JP Carver, JW Dennis
Clinical cancer research: an official journal of the American Association …, 1995
Metabolism, cell surface organization, and disease
JW Dennis, IR Nabi, M Demetriou
Cell 139 (7), 1229-1241, 2009
β1–6 branched oligosaccharides as a marker of tumor progression in human breast and colon neoplasia
B Fernandes, U Sagman, M Auger, M Demetrio, JW Dennis
Cancer research 51 (2), 718-723, 1991
N-Glycans in cancer progression
KS Lau, JW Dennis
Glycobiology 18 (10), 750-760, 2008
The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism
KE Wellen, C Lu, A Mancuso, JMS Lemons, M Ryczko, JW Dennis, ...
Genes & development 24 (24), 2784-2799, 2010
Lattices, rafts, and scaffolds: domain regulation of receptor signaling at the plasma membrane
P Lajoie, JG Goetz, JW Dennis, IR Nabi
Journal of Cell Biology 185 (3), 381-385, 2009
Glycosylation, galectins and cellular signaling
C Boscher, JW Dennis, IR Nabi
Current opinion in cell biology 23 (4), 383-392, 2011
A genetic map of the response to DNA damage in human cells
M Olivieri, T Cho, A Álvarez-Quilón, K Li, MJ Schellenberg, ...
Cell 182 (2), 481-496. e21, 2020
Fetuin/α2-HS glycoprotein is a transforming growth factor-β type II receptor mimic and cytokine antagonist
M Demetriou, C Binkert, B Sukhu, HC Tenenbaum, JW Dennis
Journal of biological chemistry 271 (22), 12755-12761, 1996
The galectin lattice at a glance
IR Nabi, J Shankar, JW Dennis
Journal of cell science 128 (13), 2213-2219, 2015
Phase IB clinical trial of the oligosaccharide processing inhibitor swainsonine in patients with advanced malignancies.
PE Goss, CL Reid, D Bailey, JW Dennis
Clinical cancer research: an official journal of the American Association …, 1997
Reduced contact-inhibition and substratum adhesion in epithelial cells expressing GlcNAc-transferase V.
M Demetriou, IR Nabi, M Coppolino, S Dedhar, JW Dennis
The Journal of cell biology 130 (2), 383-392, 1995
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