|Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis|
N Singh, A Gurav, S Sivaprakasam, E Brady, R Padia, H Shi, ...
Immunity 40 (1), 128-139, 2014
|Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2, 3-dioxygenase|
MD Sharma, B Baban, P Chandler, DY Hou, N Singh, H Yagita, M Azuma, ...
The Journal of clinical investigation 117 (9), 2570-2582, 2007
|Low-dose methotrexate for the prevention of atherosclerotic events|
PM Ridker, BM Everett, A Pradhan, JG MacFadyen, DH Solomon, ...
New England Journal of Medicine 380 (8), 752-762, 2019
|The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice|
S Hong, MT Wilson, I Serizawa, L Wu, N Singh, OV Naidenko, T Miura, ...
Nature medicine 7 (9), 1052-1056, 2001
|An overview on ashwagandha: a Rasayana (rejuvenator) of Ayurveda|
N Singh, M Bhalla, P de Jager, M Gilca
African Journal of Traditional, Complementary and Alternative Medicines 8 (5S), 2011
|Cutting edge: activation of NK T cells by CD1d and α-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype|
N Singh, S Hong, DC Scherer, I Serizawa, N Burdin, M Kronenberg, ...
The Journal of Immunology 163 (5), 2373-2377, 1999
|Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death|
GG Hicks, N Singh, A Nashabi, S Mai, G Bozek, L Klewes, D Arapovic, ...
Nature genetics 24 (2), 175-179, 2000
|Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis|
S Sivaprakasam, PD Prasad, N Singh
Pharmacology & therapeutics 164, 144-151, 2016
|Nonself-antigens are the cognate specificities of Foxp3+ regulatory T cells|
R Pacholczyk, J Kern, N Singh, M Iwashima, P Kraj, L Ignatowicz
Immunity 27 (3), 493-504, 2007
|Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells|
MA Zimmerman, N Singh, PM Martin, M Thangaraju, V Ganapathy, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 302 (12 …, 2012
|Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity|
W Yang, T Yu, X Huang, AJ Bilotta, L Xu, Y Lu, J Sun, F Pan, J Zhou, ...
Nature communications 11 (1), 1-18, 2020
|Transporters and receptors for short-chain fatty acids as the molecular link between colonic bacteria and the host|
V Ganapathy, M Thangaraju, PD Prasad, PM Martin, N Singh
Current opinion in pharmacology 13 (6), 869-874, 2013
|Blockade of dendritic cell development by bacterial fermentation products butyrate and propionate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases|
N Singh, M Thangaraju, PD Prasad, PM Martin, NA Lambert, T Boettger, ...
Journal of Biological Chemistry 285 (36), 27601-27608, 2010
|SLC6A14 (ATB0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive …|
S Karunakaran, S Ramachandran, V Coothankandaswamy, S Elangovan, ...
Journal of Biological Chemistry 286 (36), 31830-31838, 2011
|Lipid antigen presentation in the immune system; lessons learned from CD 1 d knockout mice|
S Hong, DC Scherer, N Singh, SK Mendiratta, I Serizawa, Y Koezuka, ...
Immunological reviews 169 (1), 31-44, 1999
|Microbiota-dependent hepatic lipogenesis mediated by stearoyl CoA desaturase 1 (SCD1) promotes metabolic syndrome in TLR5-deficient mice|
V Singh, B Chassaing, L Zhang, B San Yeoh, X Xiao, M Kumar, MT Baker, ...
Cell metabolism 22 (6), 983-996, 2015
|Modulation of immunogenicity and antigenicity of proteins by maleylation to target scavenger receptors on macrophages.|
R Abraham, N Singh, A Mukhopadhyay, SK Basu, V Bal, S Rath
The Journal of Immunology 154 (1), 1-8, 1995
|Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer …|
A Gurav, S Sivaprakasam, YD Bhutia, T Boettger, N Singh, V Ganapathy
Biochemical journal 469 (2), 267-278, 2015
|JAK-STAT-mediated chronic inflammation impairs cytotoxic T lymphocyte activation to decrease anti-PD-1 immunotherapy efficacy in pancreatic cancer|
C Lu, A Talukder, NM Savage, N Singh, K Liu
Oncoimmunology 6 (3), e1291106, 2017
|RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis|
M Zhang, X Zhu, Y Zhang, Y Cai, J Chen, S Sivaprakasam, A Gurav, W Pi, ...
Cell Death & Differentiation 22 (12), 1922-1934, 2015