Roma Sehmi
Roma Sehmi
Professor, Dept Medicine, McMaster University
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Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia
SG Smith, R Chen, M Kjarsgaard, C Huang, JP Oliveria, PM O'Byrne, ...
Journal of Allergy and Clinical Immunology 137 (1), 75-86. e8, 2016
Allergen-induced increases in IL-5 receptor alpha-subunit expression on bone marrow-derived CD34+ cells from asthmatic subjects. A novel marker of progenitor cell commitment …
R Sehmi, LJ Wood, R Watson, R Foley, Q Hamid, PM O'Byrne, ...
The Journal of clinical investigation 100 (10), 2466-2475, 1997
Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects
R Sehmi, AJ Wardlaw, O Cromwell, K Kurihara, P Waltmann, AB Kay
Anti–IL-5 (mepolizumab) therapy induces bone marrow eosinophil maturational arrest and decreases eosinophil progenitors in the bronchial mucosa of atopic asthmatics
A Menzies-Gow, P Flood-Page, R Sehmi, J Burman, Q Hamid, ...
Journal of Allergy and Clinical Immunology 111 (4), 714-719, 2003
Increased levels of CD34+ hemopoietic progenitor cells in atopic subjects.
R Sehmi, K Howie, DR Sutherland, W Schragge, PM O'Byrne, JA Denburg
American journal of respiratory cell and molecular biology 15 (5), 645-655, 1996
Systemic aspects of allergic disease: bone marrow responses
JA Denburg, R Sehmi, H Saito, J Pil-Seob, MD Inman, PM O’Byrne
Journal of allergy and clinical immunology 106 (5), S242-S246, 2000
Cysteinyl leukotrienes promote human airway smooth muscle migration
K Parameswaran, G Cox, K Radford, LJ Janssen, R Sehmi, PM O'Byrne
American journal of respiratory and critical care medicine 166 (5), 738-742, 2002
Fish oil supplementation in pregnancy modifies neonatal progenitors at birth in infants at risk of atopy
JA Denburg, HM Hatfield, MM Cyr, L Hayes, PG Holt, R Sehmi, ...
Pediatric research 57 (2), 276-281, 2005
Weight-adjusted intravenous reslizumab in severe asthma with inadequate response to fixed-dose subcutaneous mepolizumab
M Mukherjee, F Aleman Paramo, M Kjarsgaard, B Salter, G Nair, ...
American Journal of Respiratory and Critical Care Medicine 197 (1), 38-46, 2018
Allergen‐induced fluctuation in CC chemokine receptor 3 expression on bone marrow CD34+ cells from asthmatic subjects: significance for mobilization of …
R Sehmi, S Dorman, A Baatjes, R Watson, R Foley, S Ying, DS Robinson, ...
Immunology 109 (4), 536-546, 2003
Interleukin‐8 is a chemo‐attractant for eosinophils purified from subjects with a blood eosinophilia but not from normal healthy subjects
R Sehmi, O Cromwell, AJ Wardlaw, R Moqbel, AB Kay
Clinical & Experimental Allergy 23 (12), 1027-1036, 1993
Anti-IL5 therapy for asthma and beyond
M Mukherjee, R Sehmi, P Nair
World Allergy Organization Journal 7, 32, 2014
The accumulation of 111In-eosinophils induced by inflammatory mediators, in vivo.
LH Faccioli, S Nourshargh, R Moqbel, FM Williams, R Sehmi, AB Kay, ...
Immunology 73 (2), 222, 1991
Sputum CD34+IL-5Rα+ Cells Increase after Allergen: Evidence for In Situ Eosinophilopoiesis
SC Dorman, A Efthimiadis, I Babirad, RM Watson, JA Denburg, ...
American journal of respiratory and critical care medicine 169 (5), 573-577, 2004
Increased eosinophil-lineage committed progenitors in the lung of allergen-challenged mice
DS Southam, N Widmer, R Ellis, JA Hirota, MD Inman, R Sehmi
Journal of Allergy and Clinical Immunology 115 (1), 95-102, 2005
Allergen-induced increases in sputum levels of group 2 innate lymphoid cells in subjects with asthma
R Chen, SG Smith, B Salter, A El-Gammal, JP Oliveria, C Obminski, ...
American journal of respiratory and critical care medicine 196 (6), 700-712, 2017
Pathogenesis of murine experimental allergic rhinitis: a study of local and systemic consequences of IL-5 deficiency
H Saito, K Matsumoto, AE Denburg, L Crawford, R Ellis, MD Inman, ...
The Journal of Immunology 168 (6), 3017-3023, 2002
Allergen-induced increases in bone marrow T lymphocytes and interleukin-5 expression in subjects with asthma
LJ Wood, R Sehmi, S Dorman, Q Hamid, MK Tulic, RM Watson, R Foley, ...
American journal of respiratory and critical care medicine 166 (6), 883-889, 2002
Kinetics of bone marrow eosinophilopoiesis and associated cytokines after allergen inhalation
SC Dorman, R Sehmi, GM Gauvreau, RM Watson, R Foley, GL Jones, ...
American journal of respiratory and critical care medicine 169 (5), 565-572, 2004
Role of local eosinophilopoietic processes in the development of airway eosinophilia in prednisone‐dependent severe asthma
R Sehmi, SG Smith, M Kjarsgaard, K Radford, LP Boulet, C Lemiere, ...
Clinical & Experimental Allergy 46 (6), 793-802, 2016
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