Design and synthesis of conformationally constrained amino acids as versatile scaffolds and peptide mimetics S Hanessian, G McNaughton-Smith, HG Lombart, WD Lubell Tetrahedron 53 (38), 12789-12854, 1997 | 970 | 1997 |
Enantioselective synthesis of β-amino acids based on BINAP—ruthenium (II) catalyzed hydrogenation WD Lubell, M Kitamura, R Noyori Tetrahedron: Asymmetry 2 (7), 543-554, 1991 | 288 | 1991 |
Configurational stability of N-protected. alpha.-amino aldehydes WD Lubell, H Rapoport Journal of the American Chemical Society 109 (1), 236-239, 1987 | 200 | 1987 |
Azapeptides and their therapeutic potential C Proulx, D Sabatino, R Hopewell, J Spiegel, Y García Ramos, WD Lubell Future medicinal chemistry 3 (9), 1139-1164, 2011 | 197 | 2011 |
Steric Effects on the Amide Isomer Equilibrium of Prolyl Peptides. Synthesis and Conformational Analysis of N-Acetyl-5-tert-butylproline N‘-Methylamides E Beausoleil, WD Lubell Journal of the American Chemical Society 118 (51), 12902-12908, 1996 | 188 | 1996 |
Synthesis and reactivity of cyclic sulfamidites and sulfamidates RE Meléndez, WD Lubell Tetrahedron 59 (15), 2581-2616, 2003 | 185 | 2003 |
Microglia and interleukin-1β in ischemic retinopathy elicit microvascular degeneration through neuronal semaphorin-3A JC Rivera, N Sitaras, B Noueihed, D Hamel, A Madaan, T Zhou, ... Arteriosclerosis, thrombosis, and vascular biology 33 (8), 1881-1891, 2013 | 165 | 2013 |
Design, synthesis, and conformational analysis of azacycloalkane amino acids as conformationally constrained probes for mimicry of peptide secondary structures L Halab, F Gosselin, WD Lubell Peptide Science 55 (2), 101-122, 2000 | 145 | 2000 |
Use of Steric Interactions To Control Peptide Turn Geometry. Synthesis of Type VI β-Turn Mimics with 5-tert-Butylproline L Halab, WD Lubell The Journal of Organic Chemistry 64 (9), 3312-3321, 1999 | 133 | 1999 |
Cinnamoyl inhibitors of tissue transglutaminase C Pardin, JN Pelletier, WD Lubell, JW Keillor The Journal of organic chemistry 73 (15), 5766-5775, 2008 | 132 | 2008 |
Novel noncompetitive IL-1 receptor–biased ligand prevents infection-and inflammation-induced preterm birth M Nadeau-Vallée, C Quiniou, J Palacios, X Hou, A Erfani, A Madaan, ... The Journal of Immunology 195 (7), 3402-3415, 2015 | 128 | 2015 |
Pyrrole protection B Jolicoeur, EE Chapman, A Thompson, WD Lubell Tetrahedron 62 (50), 11531-11563, 2006 | 128 | 2006 |
4-substituted piperidine derivatives L McKerracher, E Thouin, W Lubell, R Snow, K Gingras US Patent 7,572,913, 2009 | 125 | 2009 |
Antenatal suppression of IL-1 protects against inflammation-induced fetal injury and improves neonatal and developmental outcomes in mice M Nadeau-Vallée, PY Chin, L Belarbi, MÈ Brien, S Pundir, MH Berryer, ... The Journal of Immunology 198 (5), 2047-2062, 2017 | 122 | 2017 |
Systematic study of the synthesis of macrocyclic dipeptide β-turn mimics possessing 8-, 9-, and 10-membered rings by ring-closing metathesis R Kaul, S Surprenant, WD Lubell The Journal of Organic Chemistry 70 (10), 3838-3844, 2005 | 121 | 2005 |
Aza-amino acid scanning of secondary structure suited for solid-phase peptide synthesis with Fmoc chemistry and aza-amino acids with heteroatomic side chains D Boeglin, WD Lubell Journal of combinatorial chemistry 7 (6), 864-878, 2005 | 120 | 2005 |
A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2α-mediated Rho/ROCK signaling pathway E Goupil, D Tassy, C Bourguet, C Quiniou, V Wisehart, D Pétrin, ... Journal of Biological Chemistry 285 (33), 25624-25636, 2010 | 119 | 2010 |
Reversible and competitive cinnamoyl triazole inhibitors of tissue transglutaminase C Pardin, I Roy, WD Lubell, JW Keillor Chemical biology & drug design 72 (3), 189-196, 2008 | 117 | 2008 |
Aza-Amino Acid Scan for Rapid Identification of Secondary Structure Based on the Application of N-Boc-Aza1-Dipeptides in Peptide Synthesis RE Melendez, WD Lubell Journal of the American Chemical Society 126 (21), 6759-6764, 2004 | 116 | 2004 |
Design, synthesis, and application of azabicyclo [XY 0] alkanone amino acids as constrained dipeptide surrogates and peptide mimics J Cluzeau, WD Lubell Peptide Science: Original Research on Biomolecules 80 (2‐3), 98-150, 2005 | 114 | 2005 |