Graham MacLeod
Graham MacLeod
Verified email at mail.utoronto.ca
TitleCited byYear
High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities
T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ...
Cell 163 (6), 1515-1526, 2015
4662015
High-density proximity mapping reveals the subcellular organization of mRNA-associated granules and bodies
JY Youn, WH Dunham, SJ Hong, JDR Knight, M Bashkurov, GI Chen, ...
Molecular cell 69 (3), 517-532. e11, 2018
782018
The application of proteomic approaches to the study of mammalian spermatogenesis and sperm function
G MacLeod, S Varmuza
The FEBS journal 280 (22), 5635-5651, 2013
202013
New candidate targets of protein phosphatase‐1c‐gamma‐2 in mouse testis revealed by a differential phosphoproteome analysis
H Henderson, G Macleod, C Hrabchak, S Varmuza
International journal of andrology 34 (4pt1), 339-351, 2011
182011
Tandem affinity purification in transgenic mouse embryonic stem cells identifies DDOST as a novel PPP1CC2 interacting protein
G MacLeod, S Varmuza
Biochemistry 51 (48), 9678-9688, 2012
132012
Identification of potentially damaging amino acid substitutions leading to human male infertility
A Kuzmin, K Jarvi, K Lo, L Spencer, GYC Chow, G Macleod, Q Wang, ...
Biology of reproduction 81 (2), 319-326, 2009
122009
SAPCD2 controls spindle orientation and asymmetric divisions by negatively regulating the Gαi-LGN-NuMA ternary complex
CWN Chiu, C Monat, M Robitaille, M Lacomme, AM Daulat, G Macleod, ...
Developmental cell 36 (1), 50-62, 2016
92016
Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-γ
AM Opaluch, M Schneider, C Chiang, QT Nguyen, AM Maestre, ...
PloS one 9 (2), e89284, 2014
92014
PPP1CC2 can form a kinase/phosphatase complex with the testis-specific proteins TSSK1 and TSKS in the mouse testis
G MacLeod, P Shang, GT Booth, LA Mastropaolo, N Manafpoursakha, ...
Reproduction 147 (1), 1-12, 2014
62014
Comparative phosphoproteomic analysis of the mouse testis reveals changes in phosphopeptide abundance in response to Ppp1cc deletion
G MacLeod, P Taylor, L Mastropaolo, S Varmuza
EuPA Open Proteomics 2, 1-16, 2014
32014
Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells
G MacLeod, DA Bozek, N Rajakulendran, V Monteiro, M Ahmadi, ...
Cell reports 27 (3), 971-986. e9, 2019
12019
Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells
N Rajakulendran, KJ Rowland, HJ Selvadurai, M Ahmadi, NI Park, ...
Genes & development, 2019
2019
Chromatin Blueprint Of Glioblastoma Stem Cells Reveals Common Drug Candidates For Distinct Subtypes
P Guilhamon, MM Kushida, G MacLeod, SAM Tonekaboni, FMG Cavalli, ...
BioRxiv, 370726, 2018
2018
The functional genomic circuitry of human glioblastoma stem cells
G MacLeod, DA Bozek, N Rajakulendran, V Monteiro, M Ahmadi, ...
2018
Abstract A38: Genome-wide CRISPR-Cas9 screens reveal modulators of temozolomide sensitivity in glioblastoma
G MacLeod, N Rajakulendran, T Hart, H Yu, PB Dirks, S Angers
Molecular Cancer Therapeutics 16 (10 Supplement), A38-A38, 2017
2017
Abstract PR03: High-resolution detection of fitness genes and genotype-specific cancer vulnerabilities with CRISPR-Cas9 screens
T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, G Macleod, ...
Cancer Research 76 (3 Supplement), PR03-PR03, 2016
2016
Identification of Potentially Damaging Amino Acid Substitutions Leading to Male Infertility.
G MacLeod, A Kuzmin, K Jarvi, K Lo, L Spencer, G Chow, Q Wang, ...
Biology of Reproduction 81 (Suppl_1), 440-440, 2009
2009
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Articles 1–17