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Tyler J Wenzel
Tyler J Wenzel
Assistant Professor
Verified email at tylerjwenzel.com - Homepage
Title
Cited by
Cited by
Year
Short-chain fatty acids (SCFAs) alone or in combination regulate select immune functions of microglia-like cells
TJ Wenzel, EJ Gates, AL Ranger, A Klegeris
Molecular and Cellular Neuroscience 105, 103493, 2020
2422020
Targeting toll-like receptor 4 to modulate neuroinflammation in central nervous system disorders
GR Leitner, TJ Wenzel, N Marshall, EJ Gates, A Klegeris
Expert opinion on therapeutic targets 23 (10), 865-882, 2019
1972019
Novel multi-target directed ligand-based strategies for reducing neuroinflammation in Alzheimer's disease
TJ Wenzel, A Klegeris
Life sciences 207, 314-322, 2018
492018
Extracellular cardiolipin regulates select immune functions of microglia and microglia-like cells
CB Pointer, TJ Wenzel, A Klegeris
Brain research bulletin 146, 153-163, 2019
442019
Cytochrome c can be released into extracellular space and modulate functions of human astrocytes in a toll-like receptor 4-dependent manner
TJ Wenzel, E Bajwa, A Klegeris
Biochimica et Biophysica Acta (BBA)-General Subjects 1863 (11), 129400, 2019
402019
The dietary fatty acids α-linolenic acid (ALA) and linoleic acid (LA) selectively inhibit microglial nitric oxide production
JR Lowry, N Marshall, TJ Wenzel, TE Murray, A Klegeris
Molecular and Cellular Neuroscience 109, 103569, 2020
262020
Extracellular cardiolipin modulates microglial phagocytosis and cytokine secretion in a toll-like receptor (TLR) 4-dependent manner
TJ Wenzel, AL Ranger, SA McRae, A Klegeris
Journal of neuroimmunology 353, 577496, 2021
232021
Extracellular cardiolipin modulates select immune functions of astrocytes in toll‐like receptor (TLR) 4‐dependent manner
TE Murray, TJ Wenzel, S Simtchouk, BK Greuel, J Gibon, A Klegeris
Mediators of Inflammation 2022 (1), 9946439, 2022
182022
Resolution-associated molecular patterns (RAMPs) as endogenous regulators of glia functions in neuroinflammatory disease
TJ Wenzel, E Kwong, E Bajwa, A Klegeris
CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2020
142020
Cardiolipin released by microglia can act on neighboring glial cells to facilitate the uptake of amyloid-β (1–42)
TJ Wenzel, TE Murray, B Noyovitz, K Narayana, TE Gray, J Le, J He, ...
Molecular and Cellular Neuroscience 124, 103804, 2023
92023
Fundamental Neurochemistry Review: Incorporating a greater diversity of cell types, including microglia, in brain organoid cultures improves clinical translation
TJ Wenzel, J Le, J He, J Alcorn, DD Mousseau
Journal of Neurochemistry 164 (5), 560-582, 2023
8*2023
Dietary fats modulate neuroinflammation in mucin 2 knock out mice model of spontaneous colitis
TJ Wenzel, N Haskey, E Kwong, BK Greuel, EJ Gates, DL Gibson, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1868 (3), 166336, 2022
72022
Maximizing the utility of brain organoid models and overcoming their perceived limitations
TJ Wenzel, DD Mousseau
Handbook of Neural Engineering, 593-624, 2025
12025
Brain organoids engineered to give rise to glia and neural networks after 90 days in culture exhibit human-specific proteoforms
TJ Wenzel, DD Mousseau
Frontiers in Cellular Neuroscience 18, 1383688, 2024
12024
An (immuno) fluorescence protocol for monitoring monoamine oxidase A/B protein distribution within the cell
TJ Wenzel, JNK Nyarko, RM Heistad, PR Pennington, CP Phenix, ...
Monoamine oxidase: Methods and protocols, 143-161, 2022
12022
Extracellular cardiolipin modulates glial phagocytosis and cytokine secretion in a toll‐like receptor 4‐dependent manner: Developing topics
TJ Wenzel, AL Ranger, T Murray, S McRae, A Klegeris
Alzheimer's & Dementia 16, e047338, 2020
12020
Characterizing previously unrecognized effects of endogenous molecules on the phagocytic activity of glia, as well as their secretome
TJR Wenzel
University of British Columbia, 2020
12020
Human brain organoids containing microglia that have arisen innately adapt to a β-amyloid challenge better than those in which microglia are integrated by co-culture
TJ Wenzel, JD Desjarlais, DD Mousseau
Stem Cell Research & Therapy 15 (1), 258, 2024
2024
Protein expression profiles in brain organoids are more similar to those in human brain parenchyma than in mouse brain parenchyma
TJ Wenzel, DD Mousseau
bioRxiv, 2023.09. 12.557448, 2023
2023
Microglia derived from stem cells exhibit a more homeostatic and adult-like phenotype in brain organoids than in a monoculture
TJ Wenzel, J Le, R Heistad, J Alcorn, DD Mousseau
JOURNAL OF NEUROCHEMISTRY 162, 143-144, 2022
2022
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