Short-chain fatty acids (SCFAs) alone or in combination regulate select immune functions of microglia-like cells TJ Wenzel, EJ Gates, AL Ranger, A Klegeris Molecular and Cellular Neuroscience 105, 103493, 2020 | 242 | 2020 |
Targeting toll-like receptor 4 to modulate neuroinflammation in central nervous system disorders GR Leitner, TJ Wenzel, N Marshall, EJ Gates, A Klegeris Expert opinion on therapeutic targets 23 (10), 865-882, 2019 | 197 | 2019 |
Novel multi-target directed ligand-based strategies for reducing neuroinflammation in Alzheimer's disease TJ Wenzel, A Klegeris Life sciences 207, 314-322, 2018 | 49 | 2018 |
Extracellular cardiolipin regulates select immune functions of microglia and microglia-like cells CB Pointer, TJ Wenzel, A Klegeris Brain research bulletin 146, 153-163, 2019 | 44 | 2019 |
Cytochrome c can be released into extracellular space and modulate functions of human astrocytes in a toll-like receptor 4-dependent manner TJ Wenzel, E Bajwa, A Klegeris Biochimica et Biophysica Acta (BBA)-General Subjects 1863 (11), 129400, 2019 | 40 | 2019 |
The dietary fatty acids α-linolenic acid (ALA) and linoleic acid (LA) selectively inhibit microglial nitric oxide production JR Lowry, N Marshall, TJ Wenzel, TE Murray, A Klegeris Molecular and Cellular Neuroscience 109, 103569, 2020 | 26 | 2020 |
Extracellular cardiolipin modulates microglial phagocytosis and cytokine secretion in a toll-like receptor (TLR) 4-dependent manner TJ Wenzel, AL Ranger, SA McRae, A Klegeris Journal of neuroimmunology 353, 577496, 2021 | 23 | 2021 |
Extracellular cardiolipin modulates select immune functions of astrocytes in toll‐like receptor (TLR) 4‐dependent manner TE Murray, TJ Wenzel, S Simtchouk, BK Greuel, J Gibon, A Klegeris Mediators of Inflammation 2022 (1), 9946439, 2022 | 18 | 2022 |
Resolution-associated molecular patterns (RAMPs) as endogenous regulators of glia functions in neuroinflammatory disease TJ Wenzel, E Kwong, E Bajwa, A Klegeris CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2020 | 14 | 2020 |
Cardiolipin released by microglia can act on neighboring glial cells to facilitate the uptake of amyloid-β (1–42) TJ Wenzel, TE Murray, B Noyovitz, K Narayana, TE Gray, J Le, J He, ... Molecular and Cellular Neuroscience 124, 103804, 2023 | 9 | 2023 |
Fundamental Neurochemistry Review: Incorporating a greater diversity of cell types, including microglia, in brain organoid cultures improves clinical translation TJ Wenzel, J Le, J He, J Alcorn, DD Mousseau Journal of Neurochemistry 164 (5), 560-582, 2023 | 8* | 2023 |
Dietary fats modulate neuroinflammation in mucin 2 knock out mice model of spontaneous colitis TJ Wenzel, N Haskey, E Kwong, BK Greuel, EJ Gates, DL Gibson, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1868 (3), 166336, 2022 | 7 | 2022 |
Maximizing the utility of brain organoid models and overcoming their perceived limitations TJ Wenzel, DD Mousseau Handbook of Neural Engineering, 593-624, 2025 | 1 | 2025 |
Brain organoids engineered to give rise to glia and neural networks after 90 days in culture exhibit human-specific proteoforms TJ Wenzel, DD Mousseau Frontiers in Cellular Neuroscience 18, 1383688, 2024 | 1 | 2024 |
An (immuno) fluorescence protocol for monitoring monoamine oxidase A/B protein distribution within the cell TJ Wenzel, JNK Nyarko, RM Heistad, PR Pennington, CP Phenix, ... Monoamine oxidase: Methods and protocols, 143-161, 2022 | 1 | 2022 |
Extracellular cardiolipin modulates glial phagocytosis and cytokine secretion in a toll‐like receptor 4‐dependent manner: Developing topics TJ Wenzel, AL Ranger, T Murray, S McRae, A Klegeris Alzheimer's & Dementia 16, e047338, 2020 | 1 | 2020 |
Characterizing previously unrecognized effects of endogenous molecules on the phagocytic activity of glia, as well as their secretome TJR Wenzel University of British Columbia, 2020 | 1 | 2020 |
Human brain organoids containing microglia that have arisen innately adapt to a β-amyloid challenge better than those in which microglia are integrated by co-culture TJ Wenzel, JD Desjarlais, DD Mousseau Stem Cell Research & Therapy 15 (1), 258, 2024 | | 2024 |
Protein expression profiles in brain organoids are more similar to those in human brain parenchyma than in mouse brain parenchyma TJ Wenzel, DD Mousseau bioRxiv, 2023.09. 12.557448, 2023 | | 2023 |
Microglia derived from stem cells exhibit a more homeostatic and adult-like phenotype in brain organoids than in a monoculture TJ Wenzel, J Le, R Heistad, J Alcorn, DD Mousseau JOURNAL OF NEUROCHEMISTRY 162, 143-144, 2022 | | 2022 |