Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex C Rachez, BD Lemon, Z Suldan, V Bromleigh, M Gamble, AM Näär, ... Nature 398 (6730), 824-828, 1999 | 886 | 1999 |
Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes R Krishnakumar, MJ Gamble, KM Frizzell, JG Berrocal, M Kininis, ... Science 319 (5864), 819-821, 2008 | 481 | 2008 |
Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters T Zhang, JG Berrocal, KM Frizzell, MJ Gamble, ME DuMond, ... Journal of Biological Chemistry 284 (30), 20408-20417, 2009 | 283 | 2009 |
The DRIP complex and SRC-1/p160 coactivators share similar nuclear receptor binding determinants but constitute functionally distinct complexes C Rachez, M Gamble, CPB Chang, GB Atkins, MA Lazar, LP Freedman Molecular and cellular biology 20 (8), 2718-2726, 2000 | 267 | 2000 |
The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing MJ Gamble, KM Frizzell, C Yang, R Krishnakumar, WL Kraus Genes & development 24 (1), 21-32, 2010 | 202 | 2010 |
MacroH2A1 and ATM play opposing roles in paracrine senescence and the senescence-associated secretory phenotype H Chen, PD Ruiz, WM McKimpson, L Novikov, RN Kitsis, MJ Gamble Molecular cell 59 (5), 719-731, 2015 | 199 | 2015 |
QKI-mediated alternative splicing of the histone variant MacroH2A1 regulates cancer cell proliferation L Novikov, JW Park, H Chen, H Klerman, AS Jalloh, MJ Gamble Molecular and cellular biology 31 (20), 4244-4255, 2011 | 183 | 2011 |
Global Analysis of Transcriptional Regulation by Poly (ADP-ribose) Polymerase-1 and Poly (ADP-ribose) Glycohydrolase in MCF-7 Human Breast Cancer Cells*♦ KM Frizzell, MJ Gamble, JG Berrocal, T Zhang, R Krishnakumar, Y Cen, ... Journal of biological chemistry 284 (49), 33926-33938, 2009 | 149 | 2009 |
SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery MJ Gamble, RP Fisher Nature structural & molecular biology 14 (6), 548-555, 2007 | 129 | 2007 |
Genome-Wide Analysis Reveals PADI4 Cooperates with Elk-1 to Activate c-Fos Expression in Breast Cancer Cells X Zhang, MJ Gamble, S Stadler, BD Cherrington, CP Causey, ... PLoS genetics 7 (6), e1002112, 2011 | 124 | 2011 |
Regulation of poly (ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase T Zhang, JG Berrocal, J Yao, ME DuMond, R Krishnakumar, DD Ruhl, ... Journal of Biological Chemistry 287 (15), 12405-12416, 2012 | 117 | 2012 |
Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics S Larochelle, J Batliner, MJ Gamble, NM Barboza, BC Kraybill, ... Nature structural & molecular biology 13 (1), 55-62, 2006 | 115 | 2006 |
MacroH2A1. 1 and PARP-1 cooperate to regulate transcription by promoting CBP-mediated H2B acetylation H Chen, PD Ruiz, L Novikov, AD Casill, JW Park, MJ Gamble Nature structural & molecular biology 21 (11), 981-989, 2014 | 107 | 2014 |
Multiple facets of the unique histone variant macroH2A: from genomics to cell biology MJ Gamble, WL Kraus Cell cycle 9 (13), 2568-2574, 2010 | 99 | 2010 |
The histone chaperone TAF-I/SET/INHAT is required for transcription in vitro of chromatin templates MJ Gamble, H Erdjument-Bromage, P Tempst, LP Freedman, RP Fisher Molecular and cellular biology 25 (2), 797-807, 2005 | 94 | 2005 |
A coactivator code for transcription MJ Gamble, LP Freedman Trends in Biochemical Sciences 27 (4), 165-167, 2002 | 79 | 2002 |
H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction SE Healton, HD Pinto, LN Mishra, GA Hamilton, JC Wheat, ... Proceedings of the National Academy of Sciences 117 (25), 14251-14258, 2020 | 63 | 2020 |
The macroH2A1. 2 histone variant links ATRX loss to alternative telomere lengthening J Kim, C Sun, AD Tran, PJ Chin, PD Ruiz, K Wang, RJ Gibbons, ... Nature structural & molecular biology 26 (3), 213-219, 2019 | 48 | 2019 |
MacroH2A1 regulation of poly (ADP-ribose) synthesis and stability prevents necrosis and promotes DNA repair PD Ruiz, GA Hamilton, JW Park, MJ Gamble Molecular and cellular biology 40 (1), e00230-19, 2020 | 43 | 2020 |
Phosphorylation and arginine methylation mark histone H2A prior to deposition during Xenopus laevis development WL Wang, LC Anderson, JJ Nicklay, H Chen, MJ Gamble, J Shabanowitz, ... Epigenetics & Chromatin 7, 1-20, 2014 | 33 | 2014 |