A heme-dependent enzyme forms the nitrogen–nitrogen bond in piperazate YLD Hai-Yan He, Melanie A Higgins, Katherine S Ryan Nature Chemical Biology, doi:10.1038/nchembio.2411, 2017 | 108* | 2017 |
The serum metabolome of COVID-19 patients is distinctive and predictive D Shi, R Yan, L Lv, H Jiang, Y Lu, J Sheng, J Xie, W Wu, J Xia, K Xu, S Gu, ... Metabolism 118, 154739, 2021 | 102 | 2021 |
Pyridoxal phosphate-dependent reactions in the biosynthesis of natural products YL Du, KS Ryan Natural product reports 36 (3), 430-457, 2019 | 86 | 2019 |
Gamma-butyrolactone regulatory system of Streptomyces chattanoogensis links nutrient utilization, metabolism, and development YL Du, XL Shen, P Yu, LQ Bai, YQ Li Applied and environmental microbiology 77 (23), 8415-8426, 2011 | 78 | 2011 |
Identification of a novel Streptomyces chattanoogensis L10 and enhancing its natamycin production by overexpressing positive regulator ScnRII YL Du, SF Chen, LY Cheng, XL Shen, Y Tian, YQ Li The Journal of Microbiology 47, 506-513, 2009 | 73 | 2009 |
Two-Enzyme Pathway Links l-Arginine to Nitric Oxide in N-Nitroso Biosynthesis HY He, AC Henderson, YL Du, KS Ryan Journal of the American Chemical Society 141 (9), 4026-4033, 2019 | 63 | 2019 |
In vitro reconstitution of indolmycin biosynthesis reveals the molecular basis of oxazolinone assembly YL Du, LM Alkhalaf, KS Ryan Proceedings of the National Academy of Sciences 112 (9), 2717-2722, 2015 | 61 | 2015 |
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis YL Du, SZ Li, Z Zhou, SF Chen, WM Fan, YQ Li Microbiology 157 (5), 1300-1311, 2011 | 59 | 2011 |
Genome Mining‐Directed Activation of a Silent Angucycline Biosynthetic Gene Cluster in Streptomyces chattanoogensis Z Zhou, Q Xu, Q Bu, Y Guo, S Liu, Y Liu, Y Du, Y Li Chembiochem 16 (3), 496-502, 2015 | 58 | 2015 |
Molecular mechanism of azoxy bond formation for azoxymycins biosynthesis YY Guo, ZH Li, TY Xia, YL Du, XM Mao, YQ Li Nature Communications 10 (1), 4420, 2019 | 57 | 2019 |
Synthetic and biosynthetic routes to nitrogen–nitrogen bonds HY He, H Niikura, YL Du, KS Ryan Chemical Society Reviews 51 (8), 2991-3046, 2022 | 44 | 2022 |
A pyridoxal phosphate–dependent enzyme that oxidizes an unactivated carbon-carbon bond YL Du, R Singh, LM Alkhalaf, E Kuatsjah, HY He, LD Eltis, KS Ryan Nature Chemical Biology 12 (3), 194-199, 2016 | 44 | 2016 |
The rapid evolution of signal peptides is mainly caused by relaxed selection on non-synonymous and synonymous sites YD Li, ZY Xie, YL Du, Z Zhou, XM Mao, LX Lv, YQ Li Gene 436 (1-2), 8-11, 2009 | 43 | 2009 |
Probiotic Lactobacillus casei Shirota prevents acute liver injury by reshaping the gut microbiota to alleviate excessive inflammation and metabolic disorders R Yan, K Wang, Q Wang, H Jiang, Y Lu, X Chen, H Zhang, X Su, Y Du, ... Microbial Biotechnology 15 (1), 247-261, 2022 | 42 | 2022 |
The Biosynthetic Gene Cluster of Pyrazomycin—AC‐Nucleoside Antibiotic with a Rare Pyrazole Moiety G Zhao, S Yao, KW Rothchild, T Liu, Y Liu, J Lian, HY He, KS Ryan, ... ChemBioChem 21 (5), 644-649, 2020 | 40 | 2020 |
Rational and semi-rational engineering of cytochrome P450s for biotechnological applications LH Xu, YL Du Synthetic and systems biotechnology 3 (4), 283-290, 2018 | 38 | 2018 |
The-omics era-toward a systems-level understanding of Streptomyces Z Zhou, J Gu, YL Du, YQ Li, Y Wang Current genomics 12 (6), 404-416, 2011 | 34 | 2011 |
N-carbamoylation of 2, 4-diaminobutyrate reroutes the outcome in padanamide biosynthesis YL Du, DS Dalisay, RJ Andersen, KS Ryan Chemistry & Biology 20 (8), 1002-1011, 2013 | 32 | 2013 |
Reduced deformability of parasitized red blood cells as a biomarker for anti-malarial drug efficacy X Deng, SP Duffy, ME Myrand-Lapierre, K Matthews, AT Santoso, YL Du, ... Malaria journal 14, 1-9, 2015 | 25 | 2015 |
Expansion of bisindole biosynthetic pathways by combinatorial construction YL Du, KS Ryan ACS synthetic biology 4 (6), 682-688, 2015 | 25 | 2015 |