Genome-wide scan informed by age-related disease identifies loci for exceptional human longevity K Fortney, E Dobriban, P Garagnani, C Pirazzini, D Monti, D Mari, ... PLoS genetics 11 (12), e1005728, 2015 | 155 | 2015 |
Eicosanoid signaling blockade protects middle-aged mice from severe COVID-19 LYR Wong, J Zheng, K Wilhelmsen, K Li, ME Ortiz, NJ Schnicker, ... Nature, 1-9, 2022 | 120 | 2022 |
Network-based characterization of drug-regulated genes, drug targets, and toxicity M Kotlyar, K Fortney, I Jurisica Methods 57 (4), 499-507, 2012 | 98 | 2012 |
Whole-genome sequencing of the world’s oldest people HJ Gierman, K Fortney, JC Roach, NS Coles, H Li, G Glusman, GJ Markov, ... PloS one 9 (11), e112430, 2014 | 91 | 2014 |
Validation of biomarkers of aging M Moqri, C Herzog, JR Poganik, K Ying, JN Justice, DW Belsky, ... Nature Medicine, 1-13, 2024 | 73 | 2024 |
Drug repurposing using deep embeddings of gene expression profiles Y Donner, S Kazmierczak, K Fortney Molecular pharmaceutics 15 (10), 4314-4325, 2018 | 71 | 2018 |
Inferring the functions of longevity genes with modular subnetwork biomarkers of Caenorhabditis elegans aging K Fortney, M Kotlyar, I Jurisica Genome Biology, 2010 | 63 | 2010 |
Prioritizing therapeutics for lung cancer: an integrative meta-analysis of cancer gene signatures and chemogenomic data K Fortney, J Griesman, M Kotlyar, C Pastrello, M Angeli, M Sound-Tsao, ... PLoS computational biology 11 (3), e1004068, 2015 | 51 | 2015 |
Integrative computational biology for cancer research K Fortney, I Jurisica Human genetics 130 (4), 465-481, 2011 | 38 | 2011 |
Optimal multiple testing under a Gaussian prior on the effect sizes E Dobriban, K Fortney, SK Kim, AB Owen Biometrika 102 (4), 753-766, 2015 | 37 | 2015 |
Resistance to Genotoxic Stresses in Arctica islandica, the Longest Living Noncolonial Animal: Is Extreme Longevity Associated With a Multistress Resistance … Z Ungvari, D Sosnowska, JB Mason, H Gruber, SW Lee, TS Schwartz, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2012 | 35 | 2012 |
Circulating glucuronic acid predicts healthspan and longevity in humans and mice A Ho, J Sinick, T Esko, K Fischer, C Menni, J Zierer, M Matey-Hernandez, ... Aging (Albany NY) 11 (18), 7694, 2019 | 34 | 2019 |
Great desire for extended life and health amongst the American public Y Donner, K Fortney, SRG Calimport, K Pfleger, M Shah, J Betts-LaCroix Frontiers in genetics 6, 353, 2016 | 34 | 2016 |
Visual data mining of biological networks: one size does not fit all C Pastrello, D Otasek, K Fortney, G Agapito, M Cannataro, E Shirdel, ... PLoS computational biology 9 (1), e1002833, 2013 | 32 | 2013 |
Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19 LYR Wong, J Zheng, K Wilhelmsen, K Li, ME Ortiz, NJ Schnicker, ... bioRxiv, 2021 | 26 | 2021 |
Integrating untargeted metabolomics, genetically informed causal inference, and pathway enrichment to define the obesity metabolome YHH Hsu, CM Astley, JB Cole, S Vedantam, JM Mercader, A Metspalu, ... bioRxiv, 734707, 2019 | 24 | 2019 |
NetwoRx: connecting drugs to networks and phenotypes in Saccharomyces cerevisiae K Fortney, W Xie, M Kotlyar, J Griesman, Y Kotseruba, I Jurisica Nucleic acids research 41 (D1), D720-D727, 2012 | 20 | 2012 |
PAIRUP-MS: Pathway analysis and imputation to relate unknowns in profiles from mass spectrometry-based metabolite data YHH Hsu, C Churchhouse, TH Pers, JM Mercader, A Metspalu, K Fischer, ... PLOS Computational Biology 15 (1), e1006734, 2019 | 19 | 2019 |
MortalityPredictors. org: a manually-curated database of published biomarkers of human all-cause mortality MV Peto, C De la Guardia, K Winslow, A Ho, K Fortney, E Morgen Aging (Albany NY) 9 (8), 1916, 2017 | 15 | 2017 |
NAViGaTOR: Large Scalable and Interactive Navigation and Analysis of Large Graphs A Djebbari, M Ali, D Otasek, M Kotlyar, K Fortney, S Wong, A Hrvojic, ... Internet Mathematics 7 (4), 314-347, 2011 | 15 | 2011 |